ATE209034T1 - Taxolderivate - Google Patents

Taxolderivate

Info

Publication number
ATE209034T1
ATE209034T1 AT94921511T AT94921511T ATE209034T1 AT E209034 T1 ATE209034 T1 AT E209034T1 AT 94921511 T AT94921511 T AT 94921511T AT 94921511 T AT94921511 T AT 94921511T AT E209034 T1 ATE209034 T1 AT E209034T1
Authority
AT
Austria
Prior art keywords
taxol derivatives
formula
taxol
ch2opo3
ch2oso3
Prior art date
Application number
AT94921511T
Other languages
English (en)
Inventor
Larry L Klein
Clarence J Maring
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE209034T1 publication Critical patent/ATE209034T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
AT94921511T 1993-07-15 1994-07-15 Taxolderivate ATE209034T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/092,124 US5468769A (en) 1993-07-15 1993-07-15 Paclitaxel derivatives
PCT/US1994/007973 WO1995002400A1 (en) 1993-07-15 1994-07-15 Taxol derivatives

Publications (1)

Publication Number Publication Date
ATE209034T1 true ATE209034T1 (de) 2001-12-15

Family

ID=22231738

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94921511T ATE209034T1 (de) 1993-07-15 1994-07-15 Taxolderivate

Country Status (8)

Country Link
US (1) US5468769A (de)
EP (1) EP0708642B1 (de)
JP (1) JPH09500138A (de)
AT (1) ATE209034T1 (de)
CA (1) CA2165079A1 (de)
DE (1) DE69429173T2 (de)
ES (1) ES2168304T3 (de)
WO (1) WO1995002400A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5990325A (en) 1993-03-05 1999-11-23 Florida State University Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US5973160A (en) 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
DE69435002T2 (de) 1993-07-19 2008-03-20 Angiotech Pharmaceuticals, Inc., Vancouver Anti-angiogene Mittel enthaltend Taxol und einen nicht biodegradierbaren Träger und deren Verwendung
US5965566A (en) * 1993-10-20 1999-10-12 Enzon, Inc. High molecular weight polymer-based prodrugs
EP0932399B1 (de) 1996-03-12 2006-01-04 PG-TXL Company, L.P. Wasserlösliche paclitaxel-prodrogen
US6441025B2 (en) * 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
US5635531A (en) * 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
WO1998017656A1 (en) 1996-10-24 1998-04-30 Institute Armand-Frappier A family of canadensol taxanes, the semi-synthetic preparation and therapeutic use thereof
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US20020077290A1 (en) * 2000-03-17 2002-06-20 Rama Bhatt Polyglutamic acid-camptothecin conjugates and methods of preparation
EP1318794A2 (de) * 2000-09-22 2003-06-18 Bristol-Myers Squibb Company Methode zur reduktion der toxizität von kombinationschemotherapien
CN1473055A (zh) 2000-11-02 2004-02-04 ˹¡-�����ְ�֢�о��� 通过使用hsp90抑制剂提高细胞毒剂效力的方法
EP1562927B1 (de) * 2002-10-09 2009-05-13 Chatham Biotec Ltd. Thio-analoga von paclitaxel und deren vorprodukte
ES2537514T3 (es) 2003-04-04 2015-06-09 Incyte Corporation Composiciones, métodos y kits relacionados con la escisión de HER-2
US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
USH2260H1 (en) 2005-02-17 2011-07-05 Angiotech International Ag Stents combined with paclitaxel derivatives
CN101611007A (zh) 2006-12-20 2009-12-23 先灵公司 新颖的jnk抑制剂
US8658651B2 (en) 2009-09-30 2014-02-25 Merck Sharp & Dohme Corp. Compounds that are ERK inhibitors
JP6486002B2 (ja) 2010-08-23 2019-03-20 シントリックス・バイオシステムズ・インコーポレイテッドＳｙｎｔｒｉｘ Ｂｉｏｓｙｓｔｅｍｓ， Ｉｎｃ． Ｃｘｃｒ２モジュレーターとしてのアミノピリジンカルボキサミドおよびアミノピリミジンカルボキサミド
ES2671927T3 (es) 2013-08-02 2018-06-11 Syntrix Biosystems Inc. Ácido 2-[5-[N-(4-fluorofenil)carbamoil]pirimidin-2-ilsulfanilmetil]-4-(trifluorometoxi)fenil]borónico
US8969365B2 (en) 2013-08-02 2015-03-03 Syntrix Biosystems, Inc. Thiopyrimidinecarboxamides as CXCR1/2 modulators
US10046002B2 (en) 2013-08-02 2018-08-14 Syntrix Biosystems Inc. Method for treating cancer using chemokine antagonists
US10561676B2 (en) 2013-08-02 2020-02-18 Syntrix Biosystems Inc. Method for treating cancer using dual antagonists of CXCR1 and CXCR2
WO2021055789A1 (en) 2019-09-19 2021-03-25 Leap Therapeutics, Inc. Use of dkk-1 inhibitors for treating cancer
US20240141023A1 (en) 2019-11-22 2024-05-02 Leap Therapeutics, Inc. Methods of treating cancer using dkk-1 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
EP0639186B1 (de) * 1992-04-17 1999-06-23 Abbott Laboratories Taxol-derivate

Also Published As

Publication number Publication date
EP0708642A4 (de) 1996-03-12
JPH09500138A (ja) 1997-01-07
EP0708642A1 (de) 1996-05-01
EP0708642B1 (de) 2001-11-21
CA2165079A1 (en) 1995-01-26
US5468769A (en) 1995-11-21
DE69429173T2 (de) 2002-07-04
WO1995002400A1 (en) 1995-01-26
ES2168304T3 (es) 2002-06-16
DE69429173D1 (en) 2002-01-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee