ATE207914T1 - Alpha-liponsäure in kristalliner form - Google Patents
Alpha-liponsäure in kristalliner formInfo
- Publication number
- ATE207914T1 ATE207914T1 AT99104155T AT99104155T ATE207914T1 AT E207914 T1 ATE207914 T1 AT E207914T1 AT 99104155 T AT99104155 T AT 99104155T AT 99104155 T AT99104155 T AT 99104155T AT E207914 T1 ATE207914 T1 AT E207914T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- crystalline form
- liponic acid
- enantiomer
- acid
- Prior art date
Links
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 title abstract 2
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 abstract 1
- 235000019136 lipoic acid Nutrition 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000011514 reflex Effects 0.000 abstract 1
- 229960002663 thioctic acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Seasonings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19810336A DE19810336A1 (de) | 1998-03-11 | 1998-03-11 | Alpha-Liponsäure mit neuartiger Modifikation |
| US09/074,645 US5994393A (en) | 1998-03-11 | 1998-05-08 | Alpha-lipoic acid with novel modification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE207914T1 true ATE207914T1 (de) | 2001-11-15 |
Family
ID=26044524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99104155T ATE207914T1 (de) | 1998-03-11 | 1999-03-02 | Alpha-liponsäure in kristalliner form |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5994393A (en, 2012) |
| EP (1) | EP0949258B1 (en, 2012) |
| AT (1) | ATE207914T1 (en, 2012) |
| CA (1) | CA2265276C (en, 2012) |
| CY (1) | CY1106435T1 (en, 2012) |
| DE (2) | DE19810336A1 (en, 2012) |
| DK (1) | DK0949258T3 (en, 2012) |
| ES (1) | ES2164474T3 (en, 2012) |
| IN (1) | IN186598B (en, 2012) |
| PT (1) | PT949258E (en, 2012) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19834608A1 (de) * | 1998-07-31 | 2000-02-03 | Basf Ag | Kristallmodifikation der Liponsäure |
| ATE320833T1 (de) * | 2000-06-06 | 2006-04-15 | Verwendung von einem liponsaüren -(r)- enantiomeren in kosmetika und dermatologie | |
| DE10151764A1 (de) * | 2001-10-19 | 2003-05-08 | Basf Ag | Kombination von Liponsäure und Glutamin in Lebens- und Arzneimitteln |
| US20090176864A1 (en) * | 2004-11-24 | 2009-07-09 | Hill's Pet Nutrition, Inc. | Methods For Improving Hepatic and Immune Function In An Animal |
| EP1817058B1 (en) * | 2004-11-24 | 2015-09-02 | Hill's Pet Nutrition, Inc. | Composition for use in improving liver clearance of xenobiotic substances in an animal |
| AU2005322887B2 (en) | 2004-12-30 | 2010-03-11 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| US8252742B2 (en) | 2004-12-30 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| JP2012510511A (ja) * | 2008-12-01 | 2012-05-10 | インヴアスク セラピューテイックス インコーポレイテッド | レニン−アンジオテンシン−アルドステロン系阻害剤及びリポ酸化合物を含有する組成物、並びに、レニン−アンジオテンシン−アルドステロン系に関連した疾患の治療のためのそれらの使用 |
| CN108484570B (zh) * | 2018-05-15 | 2021-05-04 | 苏州富士莱医药股份有限公司 | 一种制备硫辛酸颗粒的方法及设备 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE163849T1 (de) * | 1989-11-09 | 1998-03-15 | Asta Medica Ag | Arzneimittel enthaltend als wirkstoff r-alpha- liponsäure oder s-alpha-liponsäure |
| DE4218572A1 (de) * | 1992-06-05 | 1993-12-09 | Asta Medica Ag | Synergistische Kombination von Arzneimitteln enthaltend als Wirkstoff alpha-Liponsäure, Dihydroliponsäure, deren Metaboliten sowie die oxidierten und reduzierten Enantiomere der alpha-Liponsäure wie die R-alpha-Liponsäure oder S-alpha-Liponsäure sowie Metaboliten der alpha-Liponsäure mit den Vitaminen A, B1-6, B12, C und E |
| DE4235912C2 (de) * | 1992-10-23 | 2002-12-05 | Viatris Gmbh | Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung |
| DE4433764A1 (de) * | 1994-09-22 | 1996-03-28 | Asta Medica Ag | Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit |
-
1998
- 1998-03-11 DE DE19810336A patent/DE19810336A1/de not_active Withdrawn
- 1998-05-08 US US09/074,645 patent/US5994393A/en not_active Expired - Lifetime
-
1999
- 1999-03-02 DE DE59900364T patent/DE59900364D1/de not_active Expired - Lifetime
- 1999-03-02 DK DK99104155T patent/DK0949258T3/da active
- 1999-03-02 AT AT99104155T patent/ATE207914T1/de active
- 1999-03-02 PT PT99104155T patent/PT949258E/pt unknown
- 1999-03-02 EP EP99104155A patent/EP0949258B1/de not_active Expired - Lifetime
- 1999-03-02 ES ES99104155T patent/ES2164474T3/es not_active Expired - Lifetime
- 1999-03-11 CA CA002265276A patent/CA2265276C/en not_active Expired - Fee Related
- 1999-04-06 IN IN317CA1999 patent/IN186598B/en unknown
-
2002
- 2002-01-30 CY CY20021100024T patent/CY1106435T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2265276C (en) | 2009-09-08 |
| CY1106435T1 (el) | 2011-04-06 |
| PT949258E (pt) | 2002-04-29 |
| DK0949258T3 (da) | 2002-01-28 |
| CA2265276A1 (en) | 1999-09-11 |
| DE59900364D1 (de) | 2001-12-06 |
| EP0949258A1 (de) | 1999-10-13 |
| ES2164474T3 (es) | 2002-02-16 |
| DE19810336A1 (de) | 1999-09-23 |
| US5994393A (en) | 1999-11-30 |
| IN186598B (en, 2012) | 2001-10-06 |
| EP0949258B1 (de) | 2001-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| EEIH | Change in the person of patent owner |