ATE202091T1 - Verfahren zur chemischen racemisierung von 5- monosubstituierten hydantoinen - Google Patents
Verfahren zur chemischen racemisierung von 5- monosubstituierten hydantoinenInfo
- Publication number
- ATE202091T1 ATE202091T1 AT92118795T AT92118795T ATE202091T1 AT E202091 T1 ATE202091 T1 AT E202091T1 AT 92118795 T AT92118795 T AT 92118795T AT 92118795 T AT92118795 T AT 92118795T AT E202091 T1 ATE202091 T1 AT E202091T1
- Authority
- AT
- Austria
- Prior art keywords
- racemisation
- hydantoins
- amino acids
- monosubstituted
- case
- Prior art date
Links
- 150000001469 hydantoins Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 230000006340 racemization Effects 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 150000002500 ions Chemical class 0.000 abstract 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 230000007071 enzymatic hydrolysis Effects 0.000 abstract 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 abstract 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4137581A DE4137581A1 (de) | 1991-11-15 | 1991-11-15 | Verfahren zur chemischen racemisierung von 5-monosubstituierten hydantoinen, vorrichtung zur durchfuehrung des verfahrens und verwendung der hydantoine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE202091T1 true ATE202091T1 (de) | 2001-06-15 |
Family
ID=6444869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92118795T ATE202091T1 (de) | 1991-11-15 | 1992-11-03 | Verfahren zur chemischen racemisierung von 5- monosubstituierten hydantoinen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5449786A (de) |
| EP (1) | EP0542098B1 (de) |
| JP (1) | JPH05201992A (de) |
| AT (1) | ATE202091T1 (de) |
| DE (2) | DE4137581A1 (de) |
| DK (1) | DK0542098T3 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10050124A1 (de) | 2000-10-11 | 2002-04-25 | Degussa | Verwendung der Acetylaminosäureracemase aus Amycolatopsis orientalis Racemisierung von Carbamoylaminosäuren |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6025972A (ja) * | 1983-07-22 | 1985-02-08 | Mitsubishi Chem Ind Ltd | ヒダントイン類の製造方法 |
| HU204026B (en) * | 1984-03-12 | 1991-11-28 | Alkaloida Vegyeszeti Gyar | Process for producing di-beta-substituted phenylamino acids |
| JPS60202867A (ja) * | 1984-03-28 | 1985-10-14 | Mitsui Toatsu Chem Inc | ヒダントインの精製方法 |
| AU7166991A (en) * | 1989-11-17 | 1991-06-26 | Schering Corporation | Process for racemization of optically active arylethanolamines |
-
1991
- 1991-11-15 DE DE4137581A patent/DE4137581A1/de not_active Withdrawn
-
1992
- 1992-11-03 EP EP92118795A patent/EP0542098B1/de not_active Expired - Lifetime
- 1992-11-03 DK DK92118795T patent/DK0542098T3/da active
- 1992-11-03 DE DE59209904T patent/DE59209904D1/de not_active Expired - Fee Related
- 1992-11-03 AT AT92118795T patent/ATE202091T1/de not_active IP Right Cessation
- 1992-11-12 JP JP4301996A patent/JPH05201992A/ja active Pending
- 1992-11-16 US US07/975,170 patent/US5449786A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0542098B1 (de) | 2001-06-13 |
| DK0542098T3 (da) | 2001-07-23 |
| EP0542098A1 (de) | 1993-05-19 |
| JPH05201992A (ja) | 1993-08-10 |
| DE4137581A1 (de) | 1993-05-19 |
| DE59209904D1 (de) | 2001-07-19 |
| US5449786A (en) | 1995-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |