ATE199729T1 - Linear substituierte oligoalkylenimin- bibliotheken - Google Patents

Linear substituierte oligoalkylenimin- bibliotheken

Info

Publication number
ATE199729T1
ATE199729T1 AT94917969T AT94917969T ATE199729T1 AT E199729 T1 ATE199729 T1 AT E199729T1 AT 94917969 T AT94917969 T AT 94917969T AT 94917969 T AT94917969 T AT 94917969T AT E199729 T1 ATE199729 T1 AT E199729T1
Authority
AT
Austria
Prior art keywords
substituted
oligoalkyleneimine
repeating units
chain
libraries
Prior art date
Application number
AT94917969T
Other languages
English (en)
Inventor
Richard A Houghten
Julio Hernan Cuervo
Fred F Weitl
Original Assignee
Torrey Pines Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrey Pines Inst filed Critical Torrey Pines Inst
Application granted granted Critical
Publication of ATE199729T1 publication Critical patent/ATE199729T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/0059—Sequential processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00592—Split-and-pool, mix-and-divide processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94917969T 1993-05-18 1994-05-13 Linear substituierte oligoalkylenimin- bibliotheken ATE199729T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/063,279 US6197529B1 (en) 1990-11-21 1993-05-18 Linear substituted oligoalkyleneimine libraries
PCT/US1994/005335 WO1994026775A1 (en) 1993-05-18 1994-05-13 Linear substituted oligoalkyleneimine libraries

Publications (1)

Publication Number Publication Date
ATE199729T1 true ATE199729T1 (de) 2001-03-15

Family

ID=22048161

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94917969T ATE199729T1 (de) 1993-05-18 1994-05-13 Linear substituierte oligoalkylenimin- bibliotheken

Country Status (7)

Country Link
US (1) US6197529B1 (de)
EP (1) EP0710245B1 (de)
AT (1) ATE199729T1 (de)
AU (1) AU698224B2 (de)
CA (1) CA2163240C (de)
DE (1) DE69426885T2 (de)
WO (1) WO1994026775A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184389B1 (en) 1994-01-11 2001-02-06 Isis Pharmaceuticals, Inc. Combinatorial libraries having aminodiol monomer subunits
US6828427B1 (en) 1994-01-11 2004-12-07 Isis Pharmaceuticals, Inc. Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same
US6207826B1 (en) 1995-03-27 2001-03-27 Isis Pharmaceuticals, Inc. Macrocyclic compounds having nitrogen-containing linkages
EP0817787A4 (de) 1995-03-27 2000-09-13 Isis Pharmaceuticals Inc Makrozyklische stickstoffverbindungen
PT868427E (pt) * 1995-12-18 2003-09-30 Praecis Pharm Inc Metodos para identificar compostos que se ligam a um alvo
US6077954A (en) 1996-08-01 2000-06-20 Isis Pharmaceuticals, Inc. Substituted heterocyclic compounds
US5780241A (en) * 1996-11-05 1998-07-14 Isis Pharmaceuticals, Inc. Complex chemical libraries
US6750344B1 (en) 1997-09-05 2004-06-15 Isis Pharmaceuticals, Inc. Amine compounds and combinatorial libraries comprising same
IL143045A0 (en) * 1998-11-13 2002-04-21 Pepscan Systems Bv A method for determining a mimotope sequence
US6417195B1 (en) 1999-02-22 2002-07-09 Lion Bioscience Ag Isoquinoline derivatives and isoquinoline combinatorial libraries
US20050261474A1 (en) * 2004-05-20 2005-11-24 Mixture Sciences, Inc. Method of support-based chemical synthesis
WO2011070573A1 (en) * 2009-12-07 2011-06-16 Ben-Gurion University Of The Negev Research And Development Authority Antimicrobial water treatment membranes and production thereof
JP7401561B2 (ja) 2019-07-17 2023-12-19 ボストン サイエンティフィック サイムド，インコーポレイテッド 消化管治療のためのステント、システムおよび方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984003506A1 (en) 1983-03-08 1984-09-13 Commw Serum Lab Commission Antigenically active amino acid sequences
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4708872A (en) 1983-05-16 1987-11-24 Bristol-Meyers Company Antitumor antibiotic complex
CA1255586A (en) 1984-07-24 1989-06-13 Hendrik M. Geysen Method of determining mimotopes
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
NZ215865A (en) 1985-04-22 1988-10-28 Commw Serum Lab Commission Method of determining the active site of a receptor-binding analogue
US5010175A (en) 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
HU201964B (en) * 1989-01-13 1991-01-28 Richter Gedeon Vegyeszet Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
CZ280777B6 (cs) 1990-02-02 1996-04-17 Ústav Organické Chemie A Biochemie Avčr Mnohonásobná automatizovaná syntéza peptidů na planárních nosičích
US5182366A (en) 1990-05-15 1993-01-26 Huebner Verena D Controlled synthesis of peptide mixtures using mixed resins
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
CA2090860C (en) 1990-11-21 2003-09-16 Richard A. Houghten Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
US5541061A (en) * 1992-04-29 1996-07-30 Affymax Technologies N.V. Methods for screening factorial chemical libraries
US5300287A (en) * 1992-11-04 1994-04-05 Alcon Laboratories, Inc. Polymeric antimicrobials and their use in pharmaceutical compositions

Also Published As

Publication number Publication date
WO1994026775A1 (en) 1994-11-24
DE69426885D1 (de) 2001-04-19
EP0710245A1 (de) 1996-05-08
DE69426885T2 (de) 2001-09-06
EP0710245A4 (de) 1996-03-12
AU6948294A (en) 1994-12-12
CA2163240A1 (en) 1994-11-24
US6197529B1 (en) 2001-03-06
AU698224B2 (en) 1998-10-29
CA2163240C (en) 2004-03-30
EP0710245B1 (de) 2001-03-14

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Legal Events

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