ATE193542T1 - Verfahren und verbindungen zum screening von presynaptischen calcium kanal inhibitoren - Google Patents
Verfahren und verbindungen zum screening von presynaptischen calcium kanal inhibitorenInfo
- Publication number
- ATE193542T1 ATE193542T1 AT95941385T AT95941385T ATE193542T1 AT E193542 T1 ATE193542 T1 AT E193542T1 AT 95941385 T AT95941385 T AT 95941385T AT 95941385 T AT95941385 T AT 95941385T AT E193542 T1 ATE193542 T1 AT E193542T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compounds
- screening
- calcium channel
- presynaptic calcium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/337,602 US5623051A (en) | 1994-11-10 | 1994-11-10 | Methods and compositions for screening for presynaptic calcium channel blockers |
PCT/US1995/014776 WO1996015149A2 (en) | 1994-11-10 | 1995-11-09 | Methods and compositions for screening for presynaptic calcium channel blockers |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE193542T1 true ATE193542T1 (de) | 2000-06-15 |
Family
ID=23321213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95941385T ATE193542T1 (de) | 1994-11-10 | 1995-11-09 | Verfahren und verbindungen zum screening von presynaptischen calcium kanal inhibitoren |
Country Status (8)
Country | Link |
---|---|
US (2) | US5623051A (de) |
EP (1) | EP0791013B1 (de) |
JP (1) | JPH10509945A (de) |
AT (1) | ATE193542T1 (de) |
AU (1) | AU4282396A (de) |
CA (1) | CA2206110A1 (de) |
DE (1) | DE69517331T2 (de) |
WO (1) | WO1996015149A2 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5638972A (en) * | 1988-06-17 | 1997-06-17 | Druitt; Rodney Malcolm | Linerless closure for carbonated beverage container |
US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
US5623051A (en) * | 1994-11-10 | 1997-04-22 | University Of Washington | Methods and compositions for screening for presynaptic calcium channel blockers |
AU1084997A (en) * | 1995-12-01 | 1997-06-19 | Board Of Trustees Of The Leland Stanford Junior University | Calcium channel modulator compositions and methods |
EP0941248A1 (de) * | 1996-10-07 | 1999-09-15 | President And Fellows Of Harvard College | Sekretorosches transportprotein aus blutplättchen |
AU5900198A (en) * | 1996-12-20 | 1998-07-17 | Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for modulation of vesicular release |
AU6440798A (en) * | 1997-02-26 | 1998-09-18 | Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for modulation of vesicular release |
US20050009884A1 (en) * | 1997-06-30 | 2005-01-13 | Dreyer Evan B. | Calcium blockers to treat proliferative retinal diseases |
CA2295098A1 (en) * | 1997-06-30 | 1999-01-07 | Allergan Sales, Inc. | Calcium blockers to treat proliferative vitreoretinopathy |
WO1999004265A2 (en) * | 1997-07-17 | 1999-01-28 | Ludwig Institute For Cancer Research | Cancer associated nucleic acids and polypeptides |
US6541479B1 (en) | 1997-12-02 | 2003-04-01 | Massachusetts College Of Pharmacy | Calcium channel blockers |
US20060084660A1 (en) * | 1998-06-30 | 2006-04-20 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
US6951862B2 (en) * | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
US20040266784A1 (en) * | 1998-06-30 | 2004-12-30 | Snutch Terrance P. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
US7186726B2 (en) * | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
US6011035A (en) | 1998-06-30 | 2000-01-04 | Neuromed Technologies Inc. | Calcium channel blockers |
US6943168B2 (en) * | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
US6310059B1 (en) | 1998-06-30 | 2001-10-30 | Neuromed Technologies, Inc. | Fused ring calcium channel blockers |
US20040259866A1 (en) * | 1998-06-30 | 2004-12-23 | Snutch Terrance P. | Calcium channel blockers comprising two benzhydril moieties |
US6387897B1 (en) | 1998-06-30 | 2002-05-14 | Neuromed Technologies, Inc. | Preferentially substituted calcium channel blockers |
US6492375B2 (en) | 1998-06-30 | 2002-12-10 | Neuromed Technologies, Inc. | Partially saturated calcium channel blockers |
EP1092026A2 (de) * | 1998-07-02 | 2001-04-18 | Incyte Pharmaceuticals, Inc. | Neurotransmission-assoziierte proteine |
US6686147B1 (en) | 1998-07-15 | 2004-02-03 | Ludwig Institute For Cancer Research | Cancer associated antigens and uses therefor |
ES2253263T3 (es) * | 1999-10-13 | 2006-06-01 | The University Of British Columbia | Procedimiento para identificar compuestos que modulan la actividad neuronal. |
US6824669B1 (en) | 2000-02-17 | 2004-11-30 | Motorola, Inc. | Protein and peptide sensors using electrical detection methods |
US20020077775A1 (en) * | 2000-05-25 | 2002-06-20 | Schork Nicholas J. | Methods of DNA marker-based genetic analysis using estimated haplotype frequencies and uses thereof |
US20030195707A1 (en) * | 2000-05-25 | 2003-10-16 | Schork Nicholas J | Methods of dna marker-based genetic analysis using estimated haplotype frequencies and uses thereof |
US7049084B2 (en) | 2001-05-30 | 2006-05-23 | Ortho-Mcneil Pharmaceutical, Inc. | Neuroblastoma cell lines expressing the α2δ subunit of calcium channels and methods therefore |
US20030092039A1 (en) * | 2001-08-01 | 2003-05-15 | Third Wave Technologies, Inc. | Screening nutraceuticals |
CA2456571A1 (en) * | 2001-08-10 | 2003-02-20 | Genset Sa | Human secreted proteins, their encoding polynucleotides, and uses thereof |
EP1633343A1 (de) * | 2003-05-30 | 2006-03-15 | Neuromed Technologies, Inc. | 3-aminomethylpyrrolidine als calciumkanalantagonisten vom n-typ |
US20050227999A1 (en) * | 2004-04-09 | 2005-10-13 | Neuromed Technologies Inc. | Diarylamine derivatives as calcium channel blockers |
EP2019676A2 (de) * | 2006-05-11 | 2009-02-04 | Neuromed Pharmaceuticals, Ltd. | Verfahren zur erhöhung der bioverfügbarkeit von benzhydrylpiperazinhaltigen verbindungen |
MX2013010306A (es) | 2011-03-08 | 2013-12-09 | Zalicus Pharmaceuticals Ltd | Formulaciones de dispersion solida y metodos de uso de las mismas. |
US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
KR20160138297A (ko) * | 2014-04-04 | 2016-12-02 | 마르코 펠리지오니 | 글루타메이트 흥분독성에 의해 유발된 질병 치료를 위한 세포-투과성 펩타이드 시스템 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE68926713T2 (de) * | 1988-04-04 | 1996-11-14 | Salk Inst Biotech Ind | Calciumkanal-zusammensetzungen und verfahren |
US5386025A (en) * | 1990-02-20 | 1995-01-31 | The Salk Institute Biotechnology/Industrial Associates | Calcium channel compositions and methods |
ES2147184T3 (es) * | 1991-08-15 | 2000-09-01 | Merck & Co Inc | Composiciones de canales calcicos humanos y procedimientos. |
SG50624A1 (en) * | 1991-12-30 | 1998-07-20 | Neurex Corp | Methods of producing analgesia and enhancing opiate analgesia |
US5623051A (en) * | 1994-11-10 | 1997-04-22 | University Of Washington | Methods and compositions for screening for presynaptic calcium channel blockers |
-
1994
- 1994-11-10 US US08/337,602 patent/US5623051A/en not_active Expired - Lifetime
-
1995
- 1995-11-09 CA CA002206110A patent/CA2206110A1/en not_active Abandoned
- 1995-11-09 AT AT95941385T patent/ATE193542T1/de not_active IP Right Cessation
- 1995-11-09 DE DE69517331T patent/DE69517331T2/de not_active Expired - Fee Related
- 1995-11-09 EP EP95941385A patent/EP0791013B1/de not_active Expired - Lifetime
- 1995-11-09 AU AU42823/96A patent/AU4282396A/en not_active Abandoned
- 1995-11-09 JP JP8516272A patent/JPH10509945A/ja active Pending
- 1995-11-09 WO PCT/US1995/014776 patent/WO1996015149A2/en active IP Right Grant
- 1995-11-13 US US08/558,135 patent/US6090631A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69517331T2 (de) | 2001-01-04 |
CA2206110A1 (en) | 1996-05-23 |
WO1996015149A3 (en) | 1996-08-22 |
JPH10509945A (ja) | 1998-09-29 |
US5623051A (en) | 1997-04-22 |
EP0791013B1 (de) | 2000-05-31 |
EP0791013A2 (de) | 1997-08-27 |
AU4282396A (en) | 1996-06-06 |
US6090631A (en) | 2000-07-18 |
WO1996015149A2 (en) | 1996-05-23 |
DE69517331D1 (de) | 2000-07-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |