ATE192191T1 - Methode zur verbesserten herstellung einer produzierende zellinie durch verwendung eines fusionsprotokolls - Google Patents
Methode zur verbesserten herstellung einer produzierende zellinie durch verwendung eines fusionsprotokollsInfo
- Publication number
- ATE192191T1 ATE192191T1 AT94907760T AT94907760T ATE192191T1 AT E192191 T1 ATE192191 T1 AT E192191T1 AT 94907760 T AT94907760 T AT 94907760T AT 94907760 T AT94907760 T AT 94907760T AT E192191 T1 ATE192191 T1 AT E192191T1
- Authority
- AT
- Austria
- Prior art keywords
- cell line
- pct
- producing cell
- improved production
- fusion protocol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Data Exchanges In Wide-Area Networks (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9300509A SE9300509D0 (sv) | 1993-02-16 | 1993-02-16 | Peg treatment |
| PCT/SE1994/000123 WO1994019459A1 (en) | 1993-02-16 | 1994-02-15 | Method for obtaining an increased production of a producing celline by using a fusion protocol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE192191T1 true ATE192191T1 (de) | 2000-05-15 |
Family
ID=20388915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94907760T ATE192191T1 (de) | 1993-02-16 | 1994-02-15 | Methode zur verbesserten herstellung einer produzierende zellinie durch verwendung eines fusionsprotokolls |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5607845A (de) |
| EP (1) | EP0684992B1 (de) |
| JP (1) | JPH08509363A (de) |
| AT (1) | ATE192191T1 (de) |
| AU (1) | AU671195B2 (de) |
| CA (1) | CA2156181C (de) |
| DE (1) | DE69424153T2 (de) |
| DK (1) | DK0684992T3 (de) |
| ES (1) | ES2147781T3 (de) |
| GR (1) | GR3034006T3 (de) |
| NZ (1) | NZ261936A (de) |
| PT (1) | PT684992E (de) |
| SE (1) | SE9300509D0 (de) |
| WO (1) | WO1994019459A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9303601D0 (sv) * | 1993-11-01 | 1993-11-01 | Kabi Pharmacia Ab | Improved cell cultivation method and medium |
| US11649449B2 (en) | 2015-09-03 | 2023-05-16 | CHO Plus, Inc. | Hybrid cell lines for high level production of a target protein |
| US10329594B1 (en) * | 2015-09-03 | 2019-06-25 | CHO Plus, Inc. | Cell lines for high level production of protein-based pharmaceuticals |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659663A (en) * | 1984-10-01 | 1987-04-21 | Board Of Regents, University Of Texas System | Methods for isolating cell fusion products |
| US4822470A (en) * | 1987-10-09 | 1989-04-18 | Baylor College Of Medicine | Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses |
| US4832814A (en) * | 1987-12-28 | 1989-05-23 | E. I. Du Pont De Nemours And Company | Electrofusion cell and method of making the same |
| GB8807271D0 (en) * | 1988-03-26 | 1988-04-27 | Preece A W | Cell fusion apparatus |
| SE465222C5 (sv) * | 1989-12-15 | 1998-02-10 | Pharmacia & Upjohn Ab | Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning |
| SE468050C (sv) * | 1991-03-15 | 1998-02-11 | Pharmacia & Upjohn Ab | Rekombinant derivat av human faktor VIII |
-
1993
- 1993-02-16 SE SE9300509A patent/SE9300509D0/xx unknown
-
1994
- 1994-02-15 AT AT94907760T patent/ATE192191T1/de active
- 1994-02-15 US US08/505,189 patent/US5607845A/en not_active Expired - Lifetime
- 1994-02-15 DE DE69424153T patent/DE69424153T2/de not_active Expired - Lifetime
- 1994-02-15 DK DK94907760T patent/DK0684992T3/da active
- 1994-02-15 PT PT94907760T patent/PT684992E/pt unknown
- 1994-02-15 ES ES94907760T patent/ES2147781T3/es not_active Expired - Lifetime
- 1994-02-15 EP EP94907760A patent/EP0684992B1/de not_active Expired - Lifetime
- 1994-02-15 NZ NZ261936A patent/NZ261936A/en not_active IP Right Cessation
- 1994-02-15 JP JP6518882A patent/JPH08509363A/ja not_active Withdrawn
- 1994-02-15 CA CA002156181A patent/CA2156181C/en not_active Expired - Fee Related
- 1994-02-15 AU AU61197/94A patent/AU671195B2/en not_active Ceased
- 1994-02-15 WO PCT/SE1994/000123 patent/WO1994019459A1/en active IP Right Grant
-
2000
- 2000-07-24 GR GR20000401692T patent/GR3034006T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0684992T3 (da) | 2000-09-18 |
| AU6119794A (en) | 1994-09-14 |
| EP0684992A1 (de) | 1995-12-06 |
| CA2156181A1 (en) | 1994-09-01 |
| WO1994019459A1 (en) | 1994-09-01 |
| JPH08509363A (ja) | 1996-10-08 |
| CA2156181C (en) | 2004-09-21 |
| NZ261936A (en) | 1996-05-28 |
| GR3034006T3 (en) | 2000-11-30 |
| US5607845A (en) | 1997-03-04 |
| PT684992E (pt) | 2000-10-31 |
| DE69424153T2 (de) | 2000-11-16 |
| SE9300509D0 (sv) | 1993-02-16 |
| AU671195B2 (en) | 1996-08-15 |
| DE69424153D1 (de) | 2000-05-31 |
| EP0684992B1 (de) | 2000-04-26 |
| ES2147781T3 (es) | 2000-10-01 |
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