ATE188126T1 - 99mtc markierte liposomen - Google Patents

99mtc markierte liposomen

Info

Publication number
ATE188126T1
ATE188126T1 AT92902553T AT92902553T ATE188126T1 AT E188126 T1 ATE188126 T1 AT E188126T1 AT 92902553 T AT92902553 T AT 92902553T AT 92902553 T AT92902553 T AT 92902553T AT E188126 T1 ATE188126 T1 AT E188126T1
Authority
AT
Austria
Prior art keywords
liposome
99mtc
labeled
encapsulated
liposomes
Prior art date
Application number
AT92902553T
Other languages
German (de)
English (en)
Inventor
William T Phillips
Robert W Klipper
James H Timmons
Alan S Rudolph
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/530,847 external-priority patent/US5158760A/en
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE188126T1 publication Critical patent/ATE188126T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1234—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT92902553T 1990-05-30 1991-05-30 99mtc markierte liposomen ATE188126T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/530,847 US5158760A (en) 1990-05-30 1990-05-30 99m TC labeled liposomes
US07/610,204 US5143713A (en) 1990-05-30 1990-11-05 99m Tc labeled liposomes
PCT/US1991/003831 WO1992001068A1 (en) 1990-05-30 1991-05-30 99mTc LABELED LIPOSOMES

Publications (1)

Publication Number Publication Date
ATE188126T1 true ATE188126T1 (de) 2000-01-15

Family

ID=27063386

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92902553T ATE188126T1 (de) 1990-05-30 1991-05-30 99mtc markierte liposomen

Country Status (9)

Country Link
US (1) US5143713A (https=)
EP (1) EP0532718B1 (https=)
AT (1) ATE188126T1 (https=)
CA (1) CA2084187C (https=)
DE (1) DE69131881T2 (https=)
DK (1) DK0532718T3 (https=)
ES (1) ES2141721T3 (https=)
GR (1) GR3032462T3 (https=)
WO (1) WO1992001068A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589189A (en) * 1994-09-14 1996-12-31 Nexstar Pharmaceuticals, Inc. Liposome dispersion
AU5905400A (en) * 1999-07-14 2001-02-05 Board Of Regents, The University Of Texas System Methods and compositions for delivery and retention of active agents to lymph nodes
MXPA02006121A (es) 1999-12-30 2004-08-23 Judith K Gwathemy Sistema de suministro de formador de quelatos de hierro.
AUPQ641100A0 (en) * 2000-03-23 2000-04-15 Australia Nuclear Science & Technology Organisation Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
GB0111279D0 (en) * 2001-05-10 2001-06-27 Nycomed Imaging As Radiolabelled liposomes
EP1423095B1 (en) 2001-08-14 2016-09-28 Tel Aviv University Future Technology Development L.P. Lipidated glycosaminoglycan particles and their use in drug and gene delivery for diagnosis and therapy
US20090060992A1 (en) * 2002-05-08 2009-03-05 University Of Central Florida Research Foundation, Inc., Preparation of magneto-vesicles with DOPE/DDAB layers
DE60335469D1 (de) * 2002-07-02 2011-02-03 Univ Texas Radioaktiv markierte verbindungen und liposome und ihre herstellungs- und anwendungsverfahren
US6987270B2 (en) * 2003-05-07 2006-01-17 General Electric Company Method to account for event losses due to positron range in positron emission tomography and assay of positron-emitting isotopes
US20040225214A1 (en) * 2003-05-07 2004-11-11 General Electric Company Method of high-throughput quantitative pet for small animal imaging using a large-bore pet scanner for the assessment of pet tracer performance
US20070003607A1 (en) * 2003-09-02 2007-01-04 Vibhudutta Awasthi Neutral liposome-encapsulated compounds and methods of making and using thereof
US20050266067A1 (en) * 2004-03-02 2005-12-01 Shiladitya Sengupta Nanocell drug delivery system
US20070053845A1 (en) * 2004-03-02 2007-03-08 Shiladitya Sengupta Nanocell drug delivery system
AR048931A1 (es) 2004-04-21 2006-06-14 Janssen Pharmaceutica Nv Proceso para la preparacion de derivados de tetralina sustituida e indano sustituido y preparacion de intermediarios de sintesis
WO2007115131A2 (en) * 2006-03-29 2007-10-11 Guilford F Timothy Liposomal reduced glutathione and 1-arginine, including other ingredient(s)
WO2006099445A2 (en) * 2005-03-14 2006-09-21 Massachusetts Institute Of Technology Nanocells for diagnosis and treatment of diseases and disorders
WO2008150261A1 (en) * 2007-06-04 2008-12-11 Wyeth Detection and quantitation of calicheamicin
GB0913442D0 (en) 2009-07-31 2009-09-16 Univ Ramot Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
US20120190609A1 (en) * 2010-08-30 2012-07-26 Martin Bader Method for producing a lipid particle, the lipid particle itself and its use
CA2868238A1 (en) 2012-04-18 2013-10-24 Ramot At Tel Aviv University Ltd. Lipidated glycosaminoglycan particles for the delivery of nucleic acids
EP3160448B1 (en) 2014-06-26 2025-08-06 Ramot at Tel-Aviv University Ltd. Liposomal formulations for delivery of nucleic acids

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335095A (en) * 1979-03-21 1982-06-15 The Radiochemical Centre Limited Indium-111 oxine complex composition
US4452774A (en) * 1982-04-30 1984-06-05 President And Fellows Of Harvard College Isonitrile radionuclide complexes for labelling and imaging agents
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
US5019369A (en) * 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4707544A (en) * 1984-11-28 1987-11-17 President And Fellows Of Harvard College Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents
US4826961A (en) * 1984-11-28 1989-05-02 President And Fellows Of Harvard College Method for preparing radiopharmaceutical complexes
DE3687467T2 (de) * 1985-03-11 1993-04-29 Amersham Int Plc Komplexe von technetium-99m mit propylen-amin-oximen.
US4735793A (en) * 1985-08-30 1988-04-05 Massachusetts Institute Of Technology Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes
US4938947A (en) * 1985-11-01 1990-07-03 Centre National De La Recherche Scientifique (Cnrs) Aerosol composition for in vivo imaging
GB8601003D0 (en) * 1986-01-16 1986-02-19 Amersham Int Plc Labelling blood cells
US4911929A (en) * 1986-08-29 1990-03-27 The United States Of America As Represented By The Secretary Of The Navy Blood substitute comprising liposome-encapsulated hemoglobin
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
EP0357773B1 (en) * 1987-02-27 1992-07-15 Terumo Kabushiki Kaisha Process for preparing liposomes
US4935223A (en) * 1988-08-04 1990-06-19 Board Of Regents, The University Of Texas System Labeled cells for use in imaging
US4925650A (en) * 1988-11-16 1990-05-15 Mallinckrodt, Inc. Technetium -99m complex for examining the renal function

Also Published As

Publication number Publication date
EP0532718A4 (https=) 1994-01-05
DK0532718T3 (da) 2000-05-08
CA2084187C (en) 2002-07-30
EP0532718B1 (en) 1999-12-29
DE69131881T2 (de) 2000-07-20
DE69131881D1 (de) 2000-02-03
GR3032462T3 (en) 2000-05-31
US5143713A (en) 1992-09-01
EP0532718A1 (en) 1993-03-24
ES2141721T3 (es) 2000-04-01
CA2084187A1 (en) 1991-12-01
WO1992001068A1 (en) 1992-01-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee