ATE187169T1 - 6-polyfluoralkoxy und 6-polyfluoralkyl-2-amino benzothiazole-derivate - Google Patents

6-polyfluoralkoxy und 6-polyfluoralkyl-2-amino benzothiazole-derivate

Info

Publication number
ATE187169T1
ATE187169T1 AT95935997T AT95935997T ATE187169T1 AT E187169 T1 ATE187169 T1 AT E187169T1 AT 95935997 T AT95935997 T AT 95935997T AT 95935997 T AT95935997 T AT 95935997T AT E187169 T1 ATE187169 T1 AT E187169T1
Authority
AT
Austria
Prior art keywords
pct
polyfluoralkoxy
polyfluoralkyl
benzothiazole derivatives
amino benzothiazole
Prior art date
Application number
AT95935997T
Other languages
English (en)
Inventor
Philip Chapelle
Claude Gaillard
Patrick Jimonet
Erik Louvel
Michel Martinet
Serge Mignani
Gerard Sanderink
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of ATE187169T1 publication Critical patent/ATE187169T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
AT95935997T 1994-10-26 1995-10-23 6-polyfluoralkoxy und 6-polyfluoralkyl-2-amino benzothiazole-derivate ATE187169T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9412796A FR2726271B1 (fr) 1994-10-26 1994-10-26 Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole

Publications (1)

Publication Number Publication Date
ATE187169T1 true ATE187169T1 (de) 1999-12-15

Family

ID=9468224

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95935997T ATE187169T1 (de) 1994-10-26 1995-10-23 6-polyfluoralkoxy und 6-polyfluoralkyl-2-amino benzothiazole-derivate

Country Status (12)

Country Link
US (1) US5795903A (de)
EP (1) EP0788491B1 (de)
JP (1) JP3882198B2 (de)
AT (1) ATE187169T1 (de)
AU (1) AU3809095A (de)
DE (1) DE69513679T2 (de)
DK (1) DK0788491T3 (de)
ES (1) ES2139247T3 (de)
FR (1) FR2726271B1 (de)
GR (1) GR3032022T3 (de)
WO (1) WO1996013492A1 (de)
ZA (1) ZA958861B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
CN1230889A (zh) 1996-09-27 1999-10-06 吉尔福特药业有限公司 NAALADase组合物和治疗谷氨酸异常及在动物中产生神经元活性的方法
FR2774592B1 (fr) * 1998-02-06 2000-03-17 Rhone Poulenc Rorer Sa Application du 2-amino-6-trifluoromethoxybenzothiazole pour la prevention ou le traitement des dysfonctionnements du cervelet
CA2456868A1 (en) * 2001-08-13 2003-02-27 Henning Boettcher Inhibitors of polyq-aggregation
EP1620413A2 (de) * 2003-04-30 2006-02-01 Cytokinetics, Inc. Verbindungen, zusammensetzungen und verfahren
WO2005077343A2 (de) * 2004-02-11 2005-08-25 Max-Delbrück-Centrum für Molekulare Medizin Neue arzneimittel und diagnostische zusammensetzungen für behandlung und diagnose von neurodegenerativen erkrankungen und amyloid-krankheiten
EP3601235A4 (de) * 2017-03-30 2020-11-18 XW Laboratories Inc. Bicyclische heteroarylderivate und deren herstellung und verwendungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US5236940A (en) * 1988-12-15 1993-08-17 Rhone-Poulenc Sante Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation
FR2649701B2 (fr) * 1988-12-15 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
ES2043070T3 (es) * 1988-12-15 1993-12-16 Rhone Poulenc Sante Procedimiento para la preparacion de derivados de la benzotiazolamina-2.

Also Published As

Publication number Publication date
ZA958861B (en) 1996-05-09
EP0788491A1 (de) 1997-08-13
ES2139247T3 (es) 2000-02-01
FR2726271B1 (fr) 1996-12-06
DE69513679D1 (de) 2000-01-05
GR3032022T3 (en) 2000-03-31
JPH10508014A (ja) 1998-08-04
AU3809095A (en) 1996-05-23
DE69513679T2 (de) 2000-06-21
EP0788491B1 (de) 1999-12-01
WO1996013492A1 (fr) 1996-05-09
JP3882198B2 (ja) 2007-02-14
US5795903A (en) 1998-08-18
DK0788491T3 (da) 2000-05-08
FR2726271A1 (fr) 1996-05-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification