ATE185969T1 - Potenzierung von nmda-antagonisten - Google Patents
Potenzierung von nmda-antagonistenInfo
- Publication number
- ATE185969T1 ATE185969T1 AT92925469T AT92925469T ATE185969T1 AT E185969 T1 ATE185969 T1 AT E185969T1 AT 92925469 T AT92925469 T AT 92925469T AT 92925469 T AT92925469 T AT 92925469T AT E185969 T1 ATE185969 T1 AT E185969T1
- Authority
- AT
- Austria
- Prior art keywords
- potentiation
- nmda antagonists
- antagonists
- nmda
- poteniating
- Prior art date
Links
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/811,204 US5318985A (en) | 1991-12-20 | 1991-12-20 | Potentiation of NMDA antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE185969T1 true ATE185969T1 (de) | 1999-11-15 |
Family
ID=25205874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92925469T ATE185969T1 (de) | 1991-12-20 | 1992-12-01 | Potenzierung von nmda-antagonisten |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5318985A (de) |
| EP (1) | EP0617616B1 (de) |
| JP (1) | JPH07504890A (de) |
| AT (1) | ATE185969T1 (de) |
| AU (1) | AU667333B2 (de) |
| CA (1) | CA2124799A1 (de) |
| DE (1) | DE69230224T2 (de) |
| DK (1) | DK0617616T3 (de) |
| NZ (1) | NZ246114A (de) |
| WO (1) | WO1993012780A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5189054A (en) * | 1990-11-02 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | 3-amidoindolyl derivatives and pharmaceutical compositions thereof |
| GB9716657D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| GB9803226D0 (en) | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| GB9902453D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902459D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902461D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902455D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902452D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB0000625D0 (en) | 2000-01-13 | 2000-03-01 | Zeneca Ltd | Chemical compounds |
| JP2005506292A (ja) * | 2001-03-08 | 2005-03-03 | エモリー ユニバーシティ | ｐＨに依存するＮＭＤＡレセプターアンタゴニスト |
| CN103497114A (zh) | 2007-06-29 | 2014-01-08 | 埃莫里大学 | 用于神经保护的nmda受体拮抗剂 |
| EP3427729A1 (de) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2608507A (en) * | 1949-08-20 | 1952-08-26 | Sharp & Dohme Inc | Dialkyl sulfamyl benzoic acids |
| US2608508A (en) * | 1949-08-20 | 1952-08-26 | Sharp & Dohme Inc | N-amylsulfamyl benzoic acids |
| JPS5756425A (en) * | 1980-09-20 | 1982-04-05 | Santen Pharmaceut Co Ltd | Hypotensor |
| US4960786A (en) * | 1989-04-24 | 1990-10-02 | Merrell Dow Pharmaceuticals Inc. | Excitatory amino acid antagonists |
| US5095009A (en) * | 1990-04-11 | 1992-03-10 | Merrell Dow Pharmaceuticals Inc. | NMDA antagonists |
| US5051442A (en) * | 1990-04-25 | 1991-09-24 | Merrell Dow Pharmaceuticals Inc. | 3-indolyl thioacetate derivatives and NMDA receptor antagonistic use thereof |
| DE4021545A1 (de) * | 1990-07-06 | 1992-01-16 | Engineering Der Voest Alpine I | Verfahren und vorrichtung zum herstellen von kunststoffaeden oder -fasern aus polymeren, insbesondere polyamid, polyester oder polypropylen |
| JP3058688B2 (ja) * | 1990-07-16 | 2000-07-04 | メレルダウファーマスーティカルズ インコーポレイテッド | 興奮性アミノ酸拮抗剤 |
| CA2104297C (en) * | 1991-02-27 | 2003-05-27 | Boyd Lynn Harrison | 4-sulfanimide-quinoline nmda antagonists |
| AU643365B2 (en) * | 1991-02-28 | 1993-11-11 | Aventisub Ii Inc. | NMDA antagonists |
| DK0603301T3 (da) * | 1991-09-09 | 1998-09-14 | Warner Lambert Co | Farmaceutisk præparat indeholdende et urikosurikon og en excitatorisk-aminosyre-antagonist |
-
1991
- 1991-12-20 US US07/811,204 patent/US5318985A/en not_active Expired - Fee Related
-
1992
- 1992-12-01 DE DE69230224T patent/DE69230224T2/de not_active Expired - Fee Related
- 1992-12-01 EP EP92925469A patent/EP0617616B1/de not_active Expired - Lifetime
- 1992-12-01 NZ NZ246114A patent/NZ246114A/en unknown
- 1992-12-01 AT AT92925469T patent/ATE185969T1/de not_active IP Right Cessation
- 1992-12-01 AU AU31509/93A patent/AU667333B2/en not_active Ceased
- 1992-12-01 DK DK92925469T patent/DK0617616T3/da active
- 1992-12-01 JP JP5511664A patent/JPH07504890A/ja active Pending
- 1992-12-01 WO PCT/US1992/010354 patent/WO1993012780A1/en not_active Ceased
- 1992-12-01 CA CA002124799A patent/CA2124799A1/en not_active Abandoned
-
1994
- 1994-02-04 US US08/191,996 patent/US5489579A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU667333B2 (en) | 1996-03-21 |
| CA2124799A1 (en) | 1993-07-08 |
| EP0617616A1 (de) | 1994-10-05 |
| WO1993012780A1 (en) | 1993-07-08 |
| DK0617616T3 (da) | 2000-04-17 |
| DE69230224D1 (de) | 1999-12-02 |
| AU3150993A (en) | 1993-07-28 |
| DE69230224T2 (de) | 2000-04-13 |
| US5318985A (en) | 1994-06-07 |
| JPH07504890A (ja) | 1995-06-01 |
| US5489579A (en) | 1996-02-06 |
| NZ246114A (en) | 1995-10-26 |
| EP0617616B1 (de) | 1999-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |