ATE181156T1 - Vorrichtung zum on line entfernen von verunreinigungen und verfahren zur kapillarelektroforese - Google Patents

Vorrichtung zum on line entfernen von verunreinigungen und verfahren zur kapillarelektroforese

Info

Publication number
ATE181156T1
ATE181156T1 AT95910118T AT95910118T ATE181156T1 AT E181156 T1 ATE181156 T1 AT E181156T1 AT 95910118 T AT95910118 T AT 95910118T AT 95910118 T AT95910118 T AT 95910118T AT E181156 T1 ATE181156 T1 AT E181156T1
Authority
AT
Austria
Prior art keywords
plug
capillary
analytes
electroforesis
impurities
Prior art date
Application number
AT95910118T
Other languages
English (en)
Inventor
John Wiktorowicz
Original Assignee
Perkin Elmer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perkin Elmer Corp filed Critical Perkin Elmer Corp
Application granted granted Critical
Publication of ATE181156T1 publication Critical patent/ATE181156T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/24—Extraction; Separation; Purification by electrochemical means
    • C07K1/26—Electrophoresis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Electrostatic Separation (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
AT95910118T 1994-01-25 1995-01-23 Vorrichtung zum on line entfernen von verunreinigungen und verfahren zur kapillarelektroforese ATE181156T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/186,080 US5423966A (en) 1994-01-25 1994-01-25 On line ion contaminant removal apparatus and method for capillary electrophoresis

Publications (1)

Publication Number Publication Date
ATE181156T1 true ATE181156T1 (de) 1999-06-15

Family

ID=22683577

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95910118T ATE181156T1 (de) 1994-01-25 1995-01-23 Vorrichtung zum on line entfernen von verunreinigungen und verfahren zur kapillarelektroforese

Country Status (8)

Country Link
US (2) US5423966A (de)
EP (1) EP0746763B1 (de)
JP (1) JP3523261B2 (de)
AT (1) ATE181156T1 (de)
AU (1) AU694657B2 (de)
CA (1) CA2181136C (de)
DE (1) DE69510185T2 (de)
WO (1) WO1995020156A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770029A (en) * 1996-07-30 1998-06-23 Soane Biosciences Integrated electrophoretic microdevices
US6020126A (en) * 1996-03-21 2000-02-01 Hsc, Reasearch And Development Limited Partnership Rapid genetic screening method
US6074827A (en) 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US6679627B1 (en) * 1997-11-04 2004-01-20 Rdc Controle Ltee Self-floating device for measuring the temperature of liquids
US6117326A (en) * 1998-06-26 2000-09-12 Rohm And Haas Company Capillary electrochromatography separation media
EP1157270A1 (de) * 1999-02-03 2001-11-28 Aclara BioSciences, Inc. Steuerung eines mehrkanal-mikrofluidiksystems
US6428666B1 (en) 1999-02-22 2002-08-06 Sandia National Laboratories Electrokinetic concentration of charged molecules
US7204922B1 (en) * 1999-07-26 2007-04-17 Johan-Valentin Kahl Method and device for the electrophoretic separation of particles, especially of macromolecules, by electrophoresis
US6223937B1 (en) 1999-11-17 2001-05-01 Kevin Schmidt Portable dispensing bottle with dissolvable wax plug at inlet
US6294064B1 (en) * 1999-11-23 2001-09-25 Beckman Coulter, Inc. Method and reagent for suppressing the injection of nucleic acid sequencing template into micro-bore capillary during DNA separation with capillary electrophoresis
US6875348B2 (en) * 2000-02-18 2005-04-05 The Board Of Trustees Of The Leland Stanford Junior University Separation column having a photopolymerized sol-gel component and associated methods
EP1126275A3 (de) * 2000-02-18 2002-12-18 The Board Of Trustees Of The Leland Stanford Junior University Kapillarsäule aus geschmolzenem Siliziumdioxid mit Photopolymerbestandteilen
US6866785B2 (en) * 2001-08-13 2005-03-15 The Board Of Trustees Of The Leland Stanford Junior University Photopolymerized sol-gel column and associated methods
US6783992B2 (en) * 2001-01-03 2004-08-31 Agilent Technologies, Inc. Methods and using chemico-mechanical microvalve devices for the selective separation of components from multi-component fluid samples
US20020144906A1 (en) * 2001-01-12 2002-10-10 Naughton Thomas F. Auxiliary heater for capillary electrophoresis instruments for enhanced sequencing applications
US7014744B2 (en) 2001-08-24 2006-03-21 Applera Corporation Method of purification and concentration using AC fields with a transfer tip
JP3979830B2 (ja) * 2001-12-04 2007-09-19 株式会社日立ハイテクノロジーズ マルチキャピラリー電気泳動装置
CN1659431A (zh) * 2002-02-19 2005-08-24 新加坡基因组研究院 用于等电聚焦的设备
US7381317B2 (en) * 2002-08-12 2008-06-03 Beckman Coulter, Inc. Methods and compositions for capillary electrophoresis (CE)
US8007725B2 (en) * 2003-11-07 2011-08-30 Princeton Biochemicals, Inc. Electrophoresis apparatus having valve system
CA2563310A1 (en) * 2003-11-07 2005-05-26 Princeton Biochemicals, Inc. Multi-dimensional electrophoresis apparatus
US20050127002A1 (en) * 2003-12-12 2005-06-16 Zare Richard N. Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
JP4329816B2 (ja) * 2004-09-15 2009-09-09 萬有製薬株式会社 サンプリング方法、サンプリング装置、ｌｏｇＤ測定方法及びｌｏｇＤ測定システム
US20070014699A1 (en) * 2005-06-23 2007-01-18 Beckman Coulter, Inc, Methods and apparatus for improving the sensitivity of capillary zone electrophoresis
US20070284308A1 (en) * 2006-06-12 2007-12-13 Zare Richard N Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
GB2483265B (en) * 2010-09-01 2018-03-28 Pillarhouse Int Ltd Soldering nozzle
CA2825149C (en) * 2011-01-31 2020-06-16 Biotype Gmbh Reduced artifact denaturing capillary electrophoresis of nucleic acids
US9766206B2 (en) 2013-09-27 2017-09-19 ProteinSimple Apparatus, systems, and methods for capillary electrophoresis
WO2019147525A1 (en) * 2018-01-26 2019-08-01 Advanced Electrofluidic Systems, Llc Method and apparatus for isolating and detecting biological and other particles
WO2025104842A1 (ja) * 2023-11-15 2025-05-22 株式会社日立ハイテク キャピラリ電気泳動装置，およびキャピラリ電気泳動分析方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5207886A (en) * 1988-02-16 1993-05-04 Applied Biosystems, Inc. Capillary electrophoresis
US4908116A (en) * 1989-06-01 1990-03-13 The Board Of Trustees At The Leland Stanford Junior University Capillary electrophoretic device employing structure permitting electrical contact through ionic movement
US5096554A (en) * 1989-08-07 1992-03-17 Applied Biosystems, Inc. Nucleic acid fractionation by counter-migration capillary electrophoresis
US5264101A (en) * 1989-11-06 1993-11-23 Applied Biosystems, Inc. Capillary electrophoresis molecular weight separation of biomolecules using a polymer-containing solution
US5015350A (en) * 1989-11-06 1991-05-14 Applied Biosystems, Inc. Flow-rate-controlled surface-charge coating for capillary electrophoresis
US5164055A (en) * 1990-01-29 1992-11-17 Applied Biosystems, Inc. High-viscosity polymer matrix and methods
US5246577A (en) * 1990-05-29 1993-09-21 Millipore Corporation Apparatus for effecting capillary electrophoresis
DE69104775T2 (de) * 1990-05-29 1995-06-01 Waters Investments Ltd Verfahren und Vorrichtung zum Durchführen der Kapillarelektroforese.
US5085756A (en) * 1990-08-21 1992-02-04 Hewlett-Packard Company Column separation system for electrophoresis with sample pretreatment
US5340452A (en) * 1991-02-01 1994-08-23 Beckman Instruments, Inc. On-column preconcentration of samples in capillary electrophoresis
US5126021A (en) * 1991-07-17 1992-06-30 Applied Biosystems Inc. Low-viscosity polymer solution for capillary electrophoresis
US5207856A (en) * 1991-07-25 1993-05-04 May Clifford H Apparatus for making a filter support tube

Also Published As

Publication number Publication date
EP0746763A1 (de) 1996-12-11
AU694657B2 (en) 1998-07-23
US5423966A (en) 1995-06-13
CA2181136A1 (en) 1995-07-27
DE69510185D1 (de) 1999-07-15
CA2181136C (en) 2000-01-11
EP0746763B1 (de) 1999-06-09
JP3523261B2 (ja) 2004-04-26
JPH09508211A (ja) 1997-08-19
AU5615596A (en) 1998-01-15
US5593559A (en) 1997-01-14
WO1995020156A1 (en) 1995-07-27
DE69510185T2 (de) 1999-12-02

Similar Documents

Publication Publication Date Title
ATE181156T1 (de) Vorrichtung zum on line entfernen von verunreinigungen und verfahren zur kapillarelektroforese
DE69621608D1 (de) Vorrichtung und verfahren für kapillarelektrophorese
DE69104775D1 (de) Verfahren und Vorrichtung zum Durchführen der Kapillarelektroforese.
ATE196949T1 (de) Verfahren und vorrichtung zur elektrochemischen veränderung von chromatographiematerial
DE3779669D1 (de) Vorrichtung fuer gas-fluessigkeitskontakt und verfahren zum entfernen von h2s.
DE69943238D1 (de) Vorrichtung und verfahren zur electrophorese
DE69700361D1 (de) Verfahren und vorrichtung zur verminderung der verzerrung einer aus einer elektrophoretischen kapillare eluirenden probenzone
DE69724871D1 (de) Verfahren und Vorrichtung zum Ausstossen von Flüssigkeit
ATE250143T1 (de) Verfahren und vorrichtung zum nachweis und zur quantifizierung von biomolekülen
DE69836648D1 (de) Vorrichtung und Verfahren zur Trennung von Flüssigkeitsbestandteilen
ATE172030T1 (de) Verfahren und detektor für trennungsprozesse
DE69512933D1 (de) Verfahren und vorrichtung zum bohren mit hochdruckflüssigkeit mit reduziertem feststoffgehalt
DE69206136D1 (de) Vorrichtung und Verfahren zur Trennung von Flüssigkeitsproben.
DE3581906D1 (de) Verfahren und vorrichtung zum detektieren von blaettern.
DE59410283D1 (de) Vorrichtung und Verfahren zur elektrophoretischen Trennung von fluiden Substanzgemischen
DE69618068D1 (de) Verfahren und Vorrichtung zum Durchführen von Text und Bildsegmentation
DE3580357D1 (de) Wirbelstromverfahren zur feststellung von oberflaechenfehlern und vorrichtung zum durchfuehren dieses verfahrens.
DE3766592D1 (de) Verfahren zur vorrichtung zum pruefen des automatischen aufblasens von reifen zur inspektion.
DE69733980D1 (de) Verfahren und Vorrichtung zum Ausstossen von Flüssigkeit
CA2176317A1 (en) Fast sampling device and sampling method for capillary electrophoresis
DE69905425D1 (de) Verfahren und vorrichtung zur trennung von bioorganischen molekülen mittels elektrophorese
AT399596B (de) Verfahren und vorrichtung zum bestimmen des orts von in flachglas vorhandenen fehlern
DE69525890D1 (de) Verfahren und Vorrichtung zum Bestimmen von anemometrischen, barometrischen und Neigungs-Parametern für Luftfahrzeuge
DE3583939D1 (de) Verfahren zum bestuecken elektronischer teile und vorrichtung dazu.
DE69404843D1 (de) Verfahren und vorrichtung zum nachweis und zur identifizierung von elektrischen kabeln

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties