ATE179992T1 - Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor - Google Patents

Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor

Info

Publication number
ATE179992T1
ATE179992T1 AT95910102T AT95910102T ATE179992T1 AT E179992 T1 ATE179992 T1 AT E179992T1 AT 95910102 T AT95910102 T AT 95910102T AT 95910102 T AT95910102 T AT 95910102T AT E179992 T1 ATE179992 T1 AT E179992T1
Authority
AT
Austria
Prior art keywords
compositions
methods
mpl receptor
platelet production
stimulating platelet
Prior art date
Application number
AT95910102T
Other languages
English (en)
Inventor
Esther S Choi
Martha M Hokom
Pamela Hunt
Janet L Nichol
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE179992T1 publication Critical patent/ATE179992T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT95910102T 1994-01-21 1995-01-18 Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor ATE179992T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/184,327 US5498599A (en) 1994-01-21 1994-01-21 Methods for stimulating platelet production

Publications (1)

Publication Number Publication Date
ATE179992T1 true ATE179992T1 (de) 1999-05-15

Family

ID=22676443

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95910102T ATE179992T1 (de) 1994-01-21 1995-01-18 Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor

Country Status (19)

Country Link
US (1) US5498599A (de)
EP (1) EP0739354B1 (de)
JP (1) JP2853905B2 (de)
KR (1) KR100222274B1 (de)
CN (1) CN1071336C (de)
AT (1) ATE179992T1 (de)
AU (1) AU682581B2 (de)
CA (1) CA2181566C (de)
DE (1) DE69509631T2 (de)
DK (1) DK0739354T3 (de)
ES (1) ES2131308T3 (de)
GR (1) GR3030262T3 (de)
HK (1) HK1004485A1 (de)
IL (1) IL112409A (de)
MX (1) MX9602905A (de)
NZ (1) NZ281395A (de)
TW (1) TW434019B (de)
WO (1) WO1995019992A1 (de)
ZA (1) ZA95526B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3877800A (en) 1999-03-30 2000-10-16 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
EP1216037A2 (de) * 1999-09-21 2002-06-26 Emory University Verfahren und zusammensetzungen zur behandlung von bluttplätchen-zusammenhängenden krankheiten, mit mpl hemmenden agenten
AU2001257056A1 (en) * 2000-04-14 2001-10-30 Genaissance Pharmaceuticals, Inc. Haplotypes of the mpl gene
EP1149906A1 (de) * 2000-04-25 2001-10-31 Pliva, Farmaceutska, Industrija, Dionicko Drustvo Thrombopoietin Rezeptormodulations Peptide
US20040028661A1 (en) * 2002-08-07 2004-02-12 Bartelmez Stephen H. Expansion of cells using thrombopoietin and anti-transforming growth factor-beta
LT1974014T (lt) 2006-01-04 2017-11-27 Baxalta Incorporated Ląstelių kultūros terpė be oligopeptidų
US7879318B2 (en) 2006-01-23 2011-02-01 Mcw Research Foundation, Inc. Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand
GB201522097D0 (en) * 2015-12-15 2016-01-27 Cellular Therapeutics Ltd Cells
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
WO2021123832A1 (en) 2019-12-20 2021-06-24 Instil Bio (Uk) Limited Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof
CN113502263B (zh) * 2021-06-09 2023-05-23 华南理工大学 一种促分化培养基及促进cd34阳性细胞分化为血小板的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198356A (en) * 1990-03-12 1993-03-30 Children's Hospital Medical Center Monophenotypic in vitro cell lines of megakaryocytic lineage, products produced thereby and methods
US5128449A (en) * 1988-07-05 1992-07-07 The University Of Tennessee Research Corporation Polypeptide and a method for its production
US5087448A (en) * 1989-02-02 1992-02-11 The Board Of Regents Of The University Of Oklahoma Enhancing growth of megakaryocytes in mammals using interleuking 6
US5032396A (en) * 1989-02-17 1991-07-16 Immunex Corporation IL-7 to stimulate platelet production
US5116951A (en) * 1990-09-19 1992-05-26 Ludwig Institute For Cancer Research Substantially pure interleukin-9 receptor and uses thereof
WO1992007074A1 (fr) * 1990-10-19 1992-04-30 Institut National De La Sante Et De La Recherche Medicale (Inserm) Polypeptide de la famille d'un recepteur de facteur de croissance, application au diagnostic et a la therapie des maladies myeloproliferatives
JP3811538B2 (ja) * 1996-03-28 2006-08-23 ロッテスノー株式会社 卵黄加工品およびそれを用いた冷菓
US7674220B2 (en) * 2007-08-09 2010-03-09 Illinois Tool Works Inc. Method and apparatus for applying hot-melt adhesive to zipper flanges and applying zipper to packages

Also Published As

Publication number Publication date
ES2131308T3 (es) 1999-07-16
NZ281395A (en) 1997-12-19
IL112409A0 (en) 1995-03-30
KR100222274B1 (ko) 1999-10-01
ZA95526B (en) 1995-12-12
JP2853905B2 (ja) 1999-02-03
AU1832495A (en) 1995-08-08
CA2181566A1 (en) 1995-07-27
MX9602905A (es) 1997-06-28
DE69509631T2 (de) 1999-12-30
DE69509631D1 (de) 1999-06-17
WO1995019992A1 (en) 1995-07-27
EP0739354A1 (de) 1996-10-30
TW434019B (en) 2001-05-16
EP0739354B1 (de) 1999-05-12
IL112409A (en) 1999-09-22
JPH09502451A (ja) 1997-03-11
HK1004485A1 (en) 1998-11-27
CN1143969A (zh) 1997-02-26
DK0739354T3 (da) 1999-11-01
CN1071336C (zh) 2001-09-19
US5498599A (en) 1996-03-12
AU682581B2 (en) 1997-10-09
GR3030262T3 (en) 1999-08-31
CA2181566C (en) 2000-05-30

Similar Documents

Publication Publication Date Title
DK0412149T3 (da) Anvendelse af IL-7 til tilvejebringelse af lægemidler til stimulering af blodpladeproduktion
ATE179992T1 (de) Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor
DE3854775D1 (de) Herzschrittmacher zur Herzstimulation
ATE84420T1 (de) Verfahren zur stimulierung von melanozyten durch lokales anbringen von alpha-msh-analogen, sowie zusammensetzungen.
DE69325256T2 (de) Insizierbare lecithin gel
ES2055911T3 (es) Compuesto farmaceutico adelgazante.
FR2623082B1 (fr) Cheville artificielle par la fixation intra-osseuse de prothese et renforts ligamentaires, ainsi que l'impacteur associe comportant des moyens de maintien de ladite cheville
ATE225176T1 (de) Verwendung von serotonin-antagonisten (5ht3) zur behandlung von fibromyalgie
DE58900183D1 (de) Ifosfamid-mesna-lyophilisat und verfahren zu dessen herstellung.
DE3650358D1 (de) Diphosphonate enthaltende pharmazeutische Zusammensetzungen zur Behandlung von Arthrosis.
DE68905342D1 (de) Verwendung von minoxidil zur wundheilung.
ATE290789T1 (de) Verwendungsmethoden von einkernigen phagozyten zur förderung der axonalen regeneration
ATE44156T1 (de) Kovalent gebundener heparin-antithrombin iiikomplex, verfahren zu dessen herstellung und seine verwendung zur behandlung von thrombusembolie.
DE3778587D1 (de) Herzschrittmacher zur stimulierung des menschlichen herzens.
DE69912827D1 (de) "ligand presenting assembly" (lpa), verfahren zu dessen herstellung und verwendungen
ATE251462T1 (de) Verfahren zur behandlung von narbengewebe
DE69429521D1 (de) Zusammensetzung und verfahren zur stimulation der reproduzierenden leistung
ATE317021T1 (de) Antisense modulierung von lfa-3
DE3888053D1 (de) Implantierbare Elektrode zur Herzstimulation.
DE69232852T2 (de) Verwendung von topotecan in der behandlung von nichtkleinzelligen lungenkarzinomen
DE60028750D1 (de) Verwendung von tagatose zur verbesserung wichtiger blutfaktoren
SU1181665A1 (ru) Способ обезболивани при хирургических вмешательствах у детей
Dixon Differentiation of somatic and autonomic nerve fibres in tissue sections
IT8149978A0 (it) Procedimento per la produzione dell'ormone umano stimolatore della tiroide
UA13003A (uk) Засіб для стимулюваhhя hавчаhhя та пам'яті

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee