ATE1777T1 - Neue chinoloncarbonsaeure-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische praeparate. - Google Patents
Neue chinoloncarbonsaeure-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische praeparate.Info
- Publication number
- ATE1777T1 ATE1777T1 AT79105088T AT79105088T ATE1777T1 AT E1777 T1 ATE1777 T1 AT E1777T1 AT 79105088 T AT79105088 T AT 79105088T AT 79105088 T AT79105088 T AT 79105088T AT E1777 T1 ATE1777 T1 AT E1777T1
- Authority
- AT
- Austria
- Prior art keywords
- acid derivatives
- quinolonecarbonic
- novel
- compounds
- processes
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- XOQQVKDBGLYPGH-UHFFFAOYSA-N 2-oxo-1h-quinoline-3-carboxylic acid Chemical class C1=CC=C2NC(=O)C(C(=O)O)=CC2=C1 XOQQVKDBGLYPGH-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical group C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782856908 DE2856908A1 (de) | 1978-12-28 | 1978-12-28 | Neue chinoloncarbonsaeure-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische praeparate |
| EP79105088A EP0012925B1 (de) | 1978-12-28 | 1979-12-11 | Neue Chinoloncarbonsäure-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE1777T1 true ATE1777T1 (de) | 1982-11-15 |
Family
ID=6058774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79105088T ATE1777T1 (de) | 1978-12-28 | 1979-12-11 | Neue chinoloncarbonsaeure-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische praeparate. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4289777A (en, 2012) |
| EP (1) | EP0012925B1 (en, 2012) |
| JP (1) | JPS5592372A (en, 2012) |
| AT (1) | ATE1777T1 (en, 2012) |
| DE (2) | DE2856908A1 (en, 2012) |
| DK (1) | DK149808C (en, 2012) |
| GB (1) | GB2044253A (en, 2012) |
| IE (1) | IE49498B1 (en, 2012) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5017583A (en) * | 1983-04-21 | 1991-05-21 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| DE3427404A1 (de) * | 1984-07-25 | 1986-01-30 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von 5,6-dihydro-2h-thiopyran-3-carboxaldehyden |
| AU2031799A (en) * | 1998-01-14 | 1999-08-02 | Uab Research Foundation, The | Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme |
| US6861448B2 (en) * | 1998-01-14 | 2005-03-01 | Virtual Drug Development, Inc. | NAD synthetase inhibitors and uses thereof |
| US6673827B1 (en) | 1999-06-29 | 2004-01-06 | The Uab Research Foundation | Methods of treating fungal infections with inhibitors of NAD synthetase enzyme |
| WO2000010996A1 (en) * | 1998-08-25 | 2000-03-02 | The Uab Research Foundation | Inhibitors of bacterial nad synthetase |
| EP1578898A2 (en) * | 2001-07-13 | 2005-09-28 | Virtual Drug Development, Inc. | Nad synthetase inhibitors and uses thereof |
| DE10317461A1 (de) * | 2003-04-16 | 2004-10-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1120870A (en) * | 1966-07-11 | 1968-07-24 | Ici Ltd | Quinoline derivatives |
| GB1305820A (en, 2012) * | 1970-09-28 | 1973-02-07 | ||
| JPS5324028A (en) * | 1976-08-19 | 1978-03-06 | Sumitomo Chem Co Ltd | Systemic bactericide for plant |
-
1978
- 1978-12-28 DE DE19782856908 patent/DE2856908A1/de not_active Withdrawn
-
1979
- 1979-12-11 EP EP79105088A patent/EP0012925B1/de not_active Expired
- 1979-12-11 DE DE7979105088T patent/DE2964033D1/de not_active Expired
- 1979-12-11 AT AT79105088T patent/ATE1777T1/de active
- 1979-12-21 GB GB7944068A patent/GB2044253A/en not_active Withdrawn
- 1979-12-21 DK DK551179A patent/DK149808C/da not_active IP Right Cessation
- 1979-12-27 US US06/107,676 patent/US4289777A/en not_active Expired - Lifetime
- 1979-12-27 JP JP16948979A patent/JPS5592372A/ja active Granted
- 1979-12-28 IE IE2515/79A patent/IE49498B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2856908A1 (de) | 1980-07-17 |
| US4289777A (en) | 1981-09-15 |
| JPS5592372A (en) | 1980-07-12 |
| DK149808C (da) | 1987-03-23 |
| EP0012925A1 (de) | 1980-07-09 |
| IE792515L (en) | 1980-06-28 |
| DE2964033D1 (en) | 1982-12-16 |
| DK149808B (da) | 1986-10-06 |
| IE49498B1 (en) | 1985-10-16 |
| GB2044253A (en) | 1980-10-15 |
| EP0012925B1 (de) | 1982-11-10 |
| JPS64951B2 (en, 2012) | 1989-01-10 |
| DK551179A (da) | 1980-06-29 |
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