ATE177423T1 - Verfahren zur herstellung von provitamin-d- verbindungen - Google Patents

Verfahren zur herstellung von provitamin-d- verbindungen

Info

Publication number
ATE177423T1
ATE177423T1 AT94901010T AT94901010T ATE177423T1 AT E177423 T1 ATE177423 T1 AT E177423T1 AT 94901010 T AT94901010 T AT 94901010T AT 94901010 T AT94901010 T AT 94901010T AT E177423 T1 ATE177423 T1 AT E177423T1
Authority
AT
Austria
Prior art keywords
pair
producing
general formula
compound represented
double bond
Prior art date
Application number
AT94901010T
Other languages
English (en)
Inventor
Noboru Kubodera
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE177423T1 publication Critical patent/ATE177423T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0042Nitrogen only
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94901010T 1992-11-27 1993-11-29 Verfahren zur herstellung von provitamin-d- verbindungen ATE177423T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP35436092 1992-11-27

Publications (1)

Publication Number Publication Date
ATE177423T1 true ATE177423T1 (de) 1999-03-15

Family

ID=18437034

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94901010T ATE177423T1 (de) 1992-11-27 1993-11-29 Verfahren zur herstellung von provitamin-d- verbindungen

Country Status (11)

Country Link
US (1) US5874598A (de)
EP (1) EP0671411B1 (de)
AT (1) ATE177423T1 (de)
CA (1) CA2150233C (de)
DE (1) DE69323894T2 (de)
DK (1) DK0671411T3 (de)
ES (1) ES2130394T3 (de)
GR (1) GR3030298T3 (de)
IL (1) IL107748A (de)
SG (1) SG79192A1 (de)
WO (1) WO1994012522A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE210642T1 (de) * 1995-01-23 2001-12-15 Chugai Pharmaceutical Co Ltd 2-substituierte vitamin-d3-derivate
TWI247001B (en) 1996-07-01 2006-01-11 Chugai Pharmaceutical Co Ltd The method for purifying vitamin d derivatives and its crystalline products
EP1070704A4 (de) * 1998-04-10 2001-11-07 Chugai Pharmaceutical Co Ltd In der 2 beta-stellung substituierte vitamin d-derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046760A (en) * 1976-07-01 1977-09-06 Merck & Co., Inc. Process for preparing 1-α-hydroxy cholesterol derivatives
US4307025A (en) * 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
US4666634A (en) * 1984-12-05 1987-05-19 Chugai Seiyaku Kabushiki Kaisha vitamin D3 derivatives having a substituent at 2-position

Also Published As

Publication number Publication date
EP0671411A1 (de) 1995-09-13
ES2130394T3 (es) 1999-07-01
IL107748A (en) 1998-08-16
IL107748A0 (en) 1994-02-27
US5874598A (en) 1999-02-23
GR3030298T3 (en) 1999-09-30
DE69323894T2 (de) 1999-08-05
DE69323894D1 (de) 1999-04-15
DK0671411T3 (da) 1999-09-27
WO1994012522A1 (en) 1994-06-09
SG79192A1 (en) 2001-03-20
EP0671411A4 (de) 1996-03-27
CA2150233C (en) 2003-12-09
EP0671411B1 (de) 1999-03-10
CA2150233A1 (en) 1994-06-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification