ATE167195T1 - Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen - Google Patents

Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen

Info

Publication number
ATE167195T1
ATE167195T1 AT94830111T AT94830111T ATE167195T1 AT E167195 T1 ATE167195 T1 AT E167195T1 AT 94830111 T AT94830111 T AT 94830111T AT 94830111 T AT94830111 T AT 94830111T AT E167195 T1 ATE167195 T1 AT E167195T1
Authority
AT
Austria
Prior art keywords
phe
ala
leu
virus
cells
Prior art date
Application number
AT94830111T
Other languages
English (en)
Inventor
Leonida Grippa
Original Assignee
Leonida Grippa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leonida Grippa filed Critical Leonida Grippa
Application granted granted Critical
Publication of ATE167195T1 publication Critical patent/ATE167195T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94830111T 1993-03-22 1994-03-16 Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen ATE167195T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93830113 1993-03-22

Publications (1)

Publication Number Publication Date
ATE167195T1 true ATE167195T1 (de) 1998-06-15

Family

ID=8215135

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94830111T ATE167195T1 (de) 1993-03-22 1994-03-16 Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen

Country Status (4)

Country Link
EP (1) EP0627444B1 (de)
AT (1) ATE167195T1 (de)
DE (1) DE69410881T2 (de)
ES (1) ES2119987T3 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1148005B (it) * 1981-04-09 1986-11-26 Leonida Grippa Tripeptide nelle sue sei combinazioni amminoacide alania fenilalanina e leucina in particolare fenil-alanina-alanina-leucina (p-a-l) aventela proprieta' di esaltare l'immunita' antivirale ed antitumorale
FR2569111B1 (fr) * 1984-08-16 1987-04-17 Rhone Poulenc Sante Nouveaux medicaments contenant des tripeptides
FR2610934B1 (fr) * 1987-02-13 1989-05-05 Adir Nouveaux derives peptidiques a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
EP0627444A1 (de) 1994-12-07
DE69410881T2 (de) 1999-02-11
DE69410881D1 (de) 1998-07-16
EP0627444B1 (de) 1998-06-10
ES2119987T3 (es) 1998-10-16

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