ATE165438T1 - Verfahren zur trocknung eines materials aus einer lösung - Google Patents

Verfahren zur trocknung eines materials aus einer lösung

Info

Publication number
ATE165438T1
ATE165438T1 AT95908365T AT95908365T ATE165438T1 AT E165438 T1 ATE165438 T1 AT E165438T1 AT 95908365 T AT95908365 T AT 95908365T AT 95908365 T AT95908365 T AT 95908365T AT E165438 T1 ATE165438 T1 AT E165438T1
Authority
AT
Austria
Prior art keywords
chamber
solution
pressure
pct
frozen
Prior art date
Application number
AT95908365T
Other languages
English (en)
Inventor
Michael Anthony Folan
Original Assignee
Kinerton Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinerton Ltd filed Critical Kinerton Ltd
Application granted granted Critical
Publication of ATE165438T1 publication Critical patent/ATE165438T1/de

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Formation And Processing Of Food Products (AREA)
  • General Preparation And Processing Of Foods (AREA)
AT95908365T 1994-02-09 1995-01-31 Verfahren zur trocknung eines materials aus einer lösung ATE165438T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE940116 1994-02-09

Publications (1)

Publication Number Publication Date
ATE165438T1 true ATE165438T1 (de) 1998-05-15

Family

ID=11040293

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95908365T ATE165438T1 (de) 1994-02-09 1995-01-31 Verfahren zur trocknung eines materials aus einer lösung

Country Status (12)

Country Link
US (1) US5727333A (de)
EP (1) EP0742888B1 (de)
JP (1) JPH09508695A (de)
AT (1) ATE165438T1 (de)
AU (1) AU680727B2 (de)
CA (1) CA2182988A1 (de)
DE (1) DE69502179D1 (de)
IL (1) IL112582A0 (de)
NZ (1) NZ279549A (de)
TW (1) TW288985B (de)
WO (1) WO1995022036A1 (de)
ZA (1) ZA95816B (de)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
NO311164B1 (no) * 1998-06-02 2001-10-22 Leiv Eiriksson Nyfotek As Fremgangsmåte for frysetörking av lösninger
ES2261195T3 (es) * 1999-04-05 2006-11-16 Mannkind Corporation Metodo de formacion de particulas finas.
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DE19936281C2 (de) * 1999-08-02 2002-04-04 Bayer Ag Verfahren zur Gefriertrocknung
SE9903236D0 (sv) * 1999-09-10 1999-09-10 Astra Ab Method to obtain microparticles
US6284283B1 (en) 1999-10-21 2001-09-04 Alkermes Controlled Therapeutics, Inc. Method of producing sub-micron particles of biologically active agents and uses thereof
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US6605438B1 (en) * 2001-03-26 2003-08-12 Louis Dischler Lyophilizing of liquid drops having arbitrary edges and application thereof to microarrays of biological reagents
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
DE10234165B4 (de) * 2002-07-26 2008-01-03 Advanced Micro Devices, Inc., Sunnyvale Verfahren zum Füllen eines Grabens, der in einem Substrat gebildet ist, mit einem isolierenden Material
US6966990B2 (en) 2002-10-11 2005-11-22 Ferro Corporation Composite particles and method for preparing
CA2508870C (en) 2002-12-30 2012-10-16 Novartis Ag Prefilming atomizer
WO2004064808A1 (en) * 2003-01-15 2004-08-05 Dow Global Technologies Inc. Drug particles obtained by freezing onto a cold surface
US6931888B2 (en) * 2003-02-07 2005-08-23 Ferro Corporation Lyophilization method and apparatus for producing particles
US7083748B2 (en) * 2003-02-07 2006-08-01 Ferro Corporation Method and apparatus for continuous particle production using supercritical fluid
US7077176B2 (en) * 2003-04-28 2006-07-18 Medical Instill Technologies, Inc. Container with valve assembly for filling and dispensing substances, and apparatus and method for filling
US20060008531A1 (en) * 2003-05-08 2006-01-12 Ferro Corporation Method for producing solid-lipid composite drug particles
WO2005061088A1 (en) * 2003-12-22 2005-07-07 Finlay Warren H Powder formation by atmospheric spray-freeze drying
JP4829229B2 (ja) 2004-07-23 2011-12-07 バイエル・テクノロジー・サービシーズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 無菌凍結、乾燥、保存、分析及び充填方法(sfd−saf法)(非経口生物薬剤用のペレット凍結乾燥法)
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
CN101379357B (zh) * 2006-02-10 2012-08-29 普莱克斯技术有限公司 冷冻干燥系统和方法
US9453675B2 (en) * 2006-02-10 2016-09-27 Sp Industries, Inc. Method of inducing nucleation of a material
US8793895B2 (en) 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
WO2007127286A2 (en) * 2006-04-24 2007-11-08 Medical Instill Technologies, Inc. Needle penetrable and laser resealable lyophilization device and related method
EP1870649A1 (de) 2006-06-20 2007-12-26 Octapharma AG Gefriertocknung zum Erzielen einer bestimmte Restfeuchte durch beschränkte Desorptionsenergiepegeln.
EP2107934B1 (de) * 2006-12-07 2019-11-20 FrieslandCampina Nederland B.V. Verfahren und vorrichtung zum sprühtrocknen
US8240065B2 (en) 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010117976A1 (en) 2009-04-09 2010-10-14 Entegrion, Inc Spray-dried blood products and methods of making same
SI3106149T1 (sl) * 2009-05-29 2020-07-31 Pearl Therapeutics, Inc. Sestavki za pljučno dostavo muskarinskih antagonistov z dolgotrajnim delovanjem in agonistov beta-2 adrenergičnega receptorja z dolgotrajnim delovanjem in povezani postopki in sistemi
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
US20110142885A1 (en) 2009-09-16 2011-06-16 Velico Medical, Inc. Spray-dried human plasma
US8407912B2 (en) 2010-09-16 2013-04-02 Velico Medical, Inc. Spray dried human plasma
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
JP5680199B2 (ja) * 2010-08-04 2015-03-04 アイエムエー ライフ ノース アメリカ インコーポレーテッド 噴霧凍結および撹拌乾燥を使用するバルク・フリーズドライ
US9945611B2 (en) 2010-08-04 2018-04-17 Ima Life North America Inc. Bulk freeze drying using spray freezing and agitated drying
EP2622293B1 (de) 2010-09-28 2016-12-28 Baxter International Inc Optimierung von nukleierung und kristallisierung zur gefriertrocknung mittels lückengefrierung
US8966782B2 (en) 2010-09-28 2015-03-03 Baxter International Inc. Optimization of nucleation and crystallization for lyophilization using gap freezing
EP2745921A3 (de) 2010-10-29 2014-10-01 Velico Medical, Inc. System und Verfahren zum Sprühtrocknen einer Flüssigkeit
US20140083628A1 (en) 2012-09-27 2014-03-27 Velico Medical, Inc. Spray drier assembly for automated spray drying
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
US8549768B2 (en) * 2011-03-11 2013-10-08 Linde Aktiengesellschaft Methods for freeze drying
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
JP5827178B2 (ja) * 2012-06-05 2015-12-02 北越紀州製紙株式会社 セルロース多孔質体及びその製造方法
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
KR101272785B1 (ko) * 2012-12-18 2013-06-11 포항공과대학교 산학협력단 고속 입자 빔을 이용한 액막 제거 방법
KR102246914B1 (ko) 2013-03-15 2021-04-30 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
HK1219059A1 (zh) 2013-03-15 2017-03-24 珍珠治疗公司 用於微粒晶体材料的状态调节的方法和系统
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
EP3030294B1 (de) 2013-08-05 2020-10-07 MannKind Corporation Insufflationsvorrichtung
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
ES2796901T3 (es) * 2014-08-04 2020-11-30 Hoffmann La Roche Aparatos y procedimientos para sellar un medicamento dentro de un dispositivo de administración médica
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN106889058B (zh) * 2017-02-20 2019-07-19 徐小杨 一种细胞冻干系统和方法
GB2564481B (en) 2017-07-14 2019-10-23 4D Pharma Leon S L U Process
FR3086739B1 (fr) * 2018-09-27 2021-02-12 Maat Pharma Recipient de lyophilisation
US20220125078A1 (en) * 2018-10-19 2022-04-28 Harvest Right, LLC Freeze Drying Methods
US11744257B1 (en) 2018-10-19 2023-09-05 Harvest Right, LLC Freeze-drying methods including vacuum freezing
US12055346B1 (en) * 2021-05-27 2024-08-06 Robert Stumbo Dryer for portable electronic devices
WO2023178184A2 (en) * 2022-03-16 2023-09-21 Biodot, Inc. Lyophilized bead manufacturing system and methods
US12246266B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Disposable for a spray drying system
US12571587B2 (en) 2022-09-15 2026-03-10 Velico Medical, Inc. Finishing apparatus for a spray drying system
WO2024059770A1 (en) * 2022-09-15 2024-03-21 Velico Medical, Inc. Rapid spray drying system
US11998861B2 (en) 2022-09-15 2024-06-04 Velico Medical, Inc. Usability of a disposable for a spray drying plasma system
US12083447B2 (en) 2022-09-15 2024-09-10 Velico Medical, Inc. Alignment of a disposable for a spray drying plasma system
US12246093B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Methods for making spray dried plasma
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system
US12539355B2 (en) 2022-09-15 2026-02-03 Velico Medical, Inc. Dryer for a spray drying system
US12225914B1 (en) 2023-05-08 2025-02-18 Harvest Right, LLC Freeze dryers and drying processes for materials with low water content

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2471035A (en) * 1943-10-02 1949-05-24 Frank E Hurd Apparatus for the desiccation of organic substances
US3362835A (en) * 1964-01-15 1968-01-09 Fmc Corp Spray freeze drying system
FR1449444A (fr) * 1965-10-09 1966-08-12 Atlas Soc As Procédé de congélation-dessiccation, et appareil pour la mise en oeuvre du procédé
US3319344A (en) * 1965-10-22 1967-05-16 Battelle Development Corp Freeze drying liquid foods
US3313032A (en) * 1966-07-28 1967-04-11 George J Malecki Freeze-drying process and apparatus
US3633283A (en) * 1967-07-06 1972-01-11 Nestle Sa Soc Ass Tech Prod Drying apparatus
FR2016600A1 (en) * 1968-08-29 1970-05-08 Leybold Heraeus Verwaltung Frozen granules for freeze drying
US3616542A (en) * 1969-02-24 1971-11-02 Earl L Rader Apparatus and processes for producing freeze dried products
US3621587A (en) * 1970-08-06 1971-11-23 Smitherm Industries Freeze drying apparatus
US3932943A (en) * 1970-08-14 1976-01-20 E. I. Du Pont De Nemours And Company Method of preparation of lyophilized biological products
US3909957A (en) * 1971-07-14 1975-10-07 Arjun Dev Passey Apparatus for freeze-drying
US4033048A (en) * 1976-01-12 1977-07-05 Clayton Van Ike Freeze drying apparatus
DE3105623A1 (de) * 1981-02-16 1982-09-02 Erhard Dipl.-Ing.agr. 8000 München Grolitsch Verfahren zur schonenden gefriertrocknung und pulverisierung von empfindlichen trocknungsguetern wie wasserhaltigen lebensmitteln
US4823478A (en) * 1987-11-30 1989-04-25 Fts Systems, Inc. Freeze dryer for unattended operation
US4848094A (en) * 1988-04-29 1989-07-18 Union Carbide Corporation Droplet freezing method and apparatus
US5257657A (en) * 1990-07-11 1993-11-02 Incre, Inc. Method for producing a free-form solid-phase object from a material in the liquid phase
US5248905A (en) * 1990-12-28 1993-09-28 National Semiconductor Corporation High speed, master/slave latch transceiver having a directly-driven slave stage
US5208998A (en) * 1991-02-25 1993-05-11 Oyler Jr James R Liquid substances freeze-drying systems and methods
DE4113512C2 (de) * 1991-04-25 1995-04-20 Grolitsch Lisbeth Verfahren und Vorrichtung zur Gefriertrocknung und Pulverisierung von Lebensmitteln
US5230162A (en) * 1992-06-26 1993-07-27 Oyler Jr James R Systems and methods for the deliquification of liquid-containing substances by flash sublimation

Also Published As

Publication number Publication date
IL112582A0 (en) 1995-05-26
WO1995022036A1 (en) 1995-08-17
NZ279549A (en) 1996-11-26
TW288985B (de) 1996-10-21
ZA95816B (en) 1995-10-09
US5727333A (en) 1998-03-17
DE69502179D1 (de) 1998-05-28
AU1671095A (en) 1995-08-29
EP0742888A1 (de) 1996-11-20
EP0742888B1 (de) 1998-04-22
JPH09508695A (ja) 1997-09-02
AU680727B2 (en) 1997-08-07
CA2182988A1 (en) 1995-08-17

Similar Documents

Publication Publication Date Title
ATE165438T1 (de) Verfahren zur trocknung eines materials aus einer lösung
EP1273330A4 (de) Verfahren und vorrichtung zur reinigung durch sublimation
DE69100206D1 (de) Verfahren zur herstellung eines fibrinogenkonzentrats aus blutplasma, vorrichtung zur durfuehrung des verfahrens und verfahren zur herstellung von fibrinogen aus diesem konzentrat.
DE69005411D1 (de) Verfahren und Vorrichtung zum Dekontaminieren von Feststoffen.
US5221756A (en) Method for the recovery and purification of maltol
GB921991A (en) Method of and apparatus for freeze drying
JPS63282305A (ja) 金属部材の付着樹脂除去方法
JPS6260182B2 (de)
ATE285826T1 (de) Lösungsmittelextraktionsverfahren
WO2000049115A3 (en) A process of obtaining natural antioxidants from plants
EP0090561B1 (de) Mehrfarbiger gefriergetrockneter Kaffee und ein Verfahren zu seiner Herstellung
JPS5579867A (en) Vacuum evaporation method
Lampky Ultrastructure of Polyangium cellulosum
IES950071A2 (en) Process for drying a material from solution
IE780472L (en) Removal of ammonia in a liquid fabric treating system
DE69128030D1 (de) Verfahren zum vergrössern des dampfdrucks durch absorption und dessen anwendungen bei hochstufigen kühl- und trennverfahren
JPS5943140B2 (ja) コ−ヒ−オイルの芳香成分除去方法およびそのための装置
JPS57207330A (en) Method of stabilizing treatment for target material
JP2716854B2 (ja) フッ素化系油を使用した油回転ポンプによる排気・回収装置
Shinagawa et al. Observations of heterogeneous nucleation of water vapor on a cold substrate
SU1264039A1 (ru) Способ получени одноступенчатых реплик дл электронно-микроскопических исследований
JPS553A (en) Production of 2-amino-3-butynoic acid
JPH0315482B2 (de)
SU958901A1 (ru) Способ получени одноступенчатых реплик с рыхлых минералов
RU2071985C1 (ru) Способ сбора ртути в технологической камере установки молекулярно-лучевой эпитаксии и установка для его осуществления

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties