ATE164166T1 - 5-alkyl, 5-(1-alkenyl) und 5-(1-alkynyl) pyrimidin-enthaltende oligodesoxynukleotide und pharmazeutische präparate enthaltend solche verbindungen - Google Patents

5-alkyl, 5-(1-alkenyl) und 5-(1-alkynyl) pyrimidin-enthaltende oligodesoxynukleotide und pharmazeutische präparate enthaltend solche verbindungen

Info

Publication number
ATE164166T1
ATE164166T1 AT94905820T AT94905820T ATE164166T1 AT E164166 T1 ATE164166 T1 AT E164166T1 AT 94905820 T AT94905820 T AT 94905820T AT 94905820 T AT94905820 T AT 94905820T AT E164166 T1 ATE164166 T1 AT E164166T1
Authority
AT
Austria
Prior art keywords
alkynyl
alkenyl
oligodeoxynucleotides
alkyl
oligodesoxynucleotides
Prior art date
Application number
AT94905820T
Other languages
English (en)
Inventor
Laszlo Oetvoes
Janos Sagi
Attila Szemzoe
Gyula Sagi
Ottone Szabolcs
Eva Ruff
Katalin Ebinger
Ferencne Tuedos
Iren Fellegvari
Original Assignee
Mta Koesponti Kemiai Kutato In
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mta Koesponti Kemiai Kutato In filed Critical Mta Koesponti Kemiai Kutato In
Application granted granted Critical
Publication of ATE164166T1 publication Critical patent/ATE164166T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT94905820T 1993-01-22 1994-01-21 5-alkyl, 5-(1-alkenyl) und 5-(1-alkynyl) pyrimidin-enthaltende oligodesoxynukleotide und pharmazeutische präparate enthaltend solche verbindungen ATE164166T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9300174A HU212717B (en) 1993-01-22 1993-01-22 Oligonucleotides containing 5-alkyl-, 5-(1-alkenyl)- or 5-(1-alkynyl)-pyrimidine bases, pharmaceutical compositions containing them and process for their preparation

Publications (1)

Publication Number Publication Date
ATE164166T1 true ATE164166T1 (de) 1998-04-15

Family

ID=10983005

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94905820T ATE164166T1 (de) 1993-01-22 1994-01-21 5-alkyl, 5-(1-alkenyl) und 5-(1-alkynyl) pyrimidin-enthaltende oligodesoxynukleotide und pharmazeutische präparate enthaltend solche verbindungen

Country Status (10)

Country Link
EP (1) EP0681586B1 (de)
JP (1) JPH08508712A (de)
KR (1) KR960700264A (de)
CN (1) CN1119017A (de)
AT (1) ATE164166T1 (de)
AU (1) AU5977894A (de)
CA (1) CA2154474A1 (de)
DE (1) DE69409097T2 (de)
HU (1) HU212717B (de)
WO (1) WO1994017094A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6166197A (en) * 1995-03-06 2000-12-26 Isis Pharmaceuticals, Inc. Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutions
WO1996027606A1 (en) 1995-03-06 1996-09-12 Isis Pharmaceuticals, Inc. Improved process for the synthesis of 2'-o-substituted pyrimidines and oligomeric compounds therefrom
US6593088B1 (en) * 1999-08-27 2003-07-15 Japan Science And Technology Corporation Reversible photocoupling nucleic acid and phosphoroamidite
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids

Also Published As

Publication number Publication date
HU9300174D0 (en) 1993-04-28
HU212717B (en) 1997-02-28
CA2154474A1 (en) 1994-08-04
CN1119017A (zh) 1996-03-20
AU5977894A (en) 1994-08-15
DE69409097T2 (de) 1998-10-29
EP0681586A1 (de) 1995-11-15
JPH08508712A (ja) 1996-09-17
KR960700264A (ko) 1996-01-19
DE69409097D1 (de) 1998-04-23
EP0681586B1 (de) 1998-03-18
WO1994017094A1 (en) 1994-08-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee