ATE163676T1 - MOLECULAR CLONES OF HIV-1 AND THEIR USE - Google Patents
MOLECULAR CLONES OF HIV-1 AND THEIR USEInfo
- Publication number
- ATE163676T1 ATE163676T1 AT91920794T AT91920794T ATE163676T1 AT E163676 T1 ATE163676 T1 AT E163676T1 AT 91920794 T AT91920794 T AT 91920794T AT 91920794 T AT91920794 T AT 91920794T AT E163676 T1 ATE163676 T1 AT E163676T1
- Authority
- AT
- Austria
- Prior art keywords
- hiv
- present
- relates
- dna segments
- molecular clones
- Prior art date
Links
- 241000713772 Human immunodeficiency virus 1 Species 0.000 title abstract 3
- 101710091045 Envelope protein Proteins 0.000 abstract 2
- 101710188315 Protein X Proteins 0.000 abstract 2
- 102100021696 Syncytin-1 Human genes 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 238000004166 bioassay Methods 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test
Abstract
The present invention relates to the HIV-1 strains MN-ST1 and BA-L which are typical United States HIV-1 isotypes. The present invention relates to DNA segments encoding the envelope protein of MN-ST1 or BA-L, to DNA constructs containing such DNA segments and to host cells transformed with such constructs. The viral isolates and envelope proteins of the present invention are of value for use in vaccines and bioassays for the detection of HIV-1 infection in biological samples, such as blood bank samples.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59949190A | 1990-10-17 | 1990-10-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE163676T1 true ATE163676T1 (en) | 1998-03-15 |
Family
ID=24399839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91920794T ATE163676T1 (en) | 1990-10-17 | 1991-10-17 | MOLECULAR CLONES OF HIV-1 AND THEIR USE |
Country Status (10)
Country | Link |
---|---|
US (3) | US5420030A (en) |
EP (1) | EP0554389B2 (en) |
JP (1) | JP2767078B2 (en) |
AT (1) | ATE163676T1 (en) |
AU (1) | AU649502B2 (en) |
CA (1) | CA2093427C (en) |
DE (1) | DE69129034T3 (en) |
DK (1) | DK0554389T4 (en) |
ES (1) | ES2115622T5 (en) |
WO (1) | WO1992006990A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1341482C (en) * | 1984-10-31 | 2005-05-10 | Paul A. Luciw | Process for preparing fragments of aids-associated retroviruses |
DE4228787A1 (en) * | 1992-08-29 | 1994-03-03 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | New HIV-1 virus isolates of a subtype, vaccines against HIV-1 virus infections of this subtype and process for their preparation, use of the HIV-1 virus isolates |
JP3277045B2 (en) * | 1992-10-06 | 2002-04-22 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | HIV-group retroviruses and uses thereof |
WO1994028929A1 (en) | 1993-06-07 | 1994-12-22 | Genentech, Inc. | Hiv envelope polypeptides |
ATE241385T1 (en) * | 1993-08-11 | 2003-06-15 | Wyeth Corp | RECOMBINANT ADENOVIRUS VACCINES |
DE4405810A1 (en) | 1994-02-23 | 1995-08-24 | Behringwerke Ag | Peptides derived from a retrovirus from the HIV group and their use |
US6585979B1 (en) | 1996-07-08 | 2003-07-01 | Genentech, Inc. | HIV envelope polypeptides and immunogenic composition |
FR2756843B1 (en) | 1996-12-09 | 1999-01-22 | Inst Nat Sante Rech Med | NON-M NON-O HIV-1 STRAINS, FRAGMENTS AND APPLICATIONS |
US6001558A (en) * | 1997-06-25 | 1999-12-14 | Ortho Clinical Diagnostics, Inc. | Amplification and detection of HIV-1 and/or HIV 2 |
US6322976B1 (en) * | 1998-05-28 | 2001-11-27 | Medical Research Council | Compositions and methods of disease diagnosis and therapy |
US6908612B2 (en) | 1999-10-08 | 2005-06-21 | University Of Maryland Biotechnology Institute | Virus coat protein/receptor chimeras and methods of use |
US7311920B1 (en) | 1999-10-08 | 2007-12-25 | University Of Maryland Biotechnology Institute | Virus coat protein/receptor chimeras and methods of use |
EP2020450B9 (en) | 2000-09-01 | 2011-09-14 | Gen-Probe Incorporated | Amplification of HIV-1 sequences for detection of sequences associated with drug-resistance mutations |
US6582920B2 (en) | 2000-09-01 | 2003-06-24 | Gen-Probe Incorporated | Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations |
US20080057492A1 (en) * | 2002-05-10 | 2008-03-06 | Quinnan Jr Gerald V | Interacting site for gp41 on gp120 of hiv-1 |
CA2505583C (en) * | 2002-12-03 | 2014-07-15 | University Of Massachusetts | Polyvalent, primary hiv-1 glycoprotein dna vaccines and vaccination methods |
JP4038679B2 (en) * | 2003-05-13 | 2008-01-30 | 住友電気工業株式会社 | Fixing jig for semiconductor laser bar |
WO2005016952A2 (en) * | 2003-05-19 | 2005-02-24 | Duke University | Polyvalent immunogen |
US8617816B2 (en) * | 2007-03-16 | 2013-12-31 | 454 Life Sciences, A Roche Company | System and method for detection of HIV drug resistant variants |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6226300A (en) * | 1984-10-10 | 1987-02-04 | セントコ−・インコ−ポレ−テツド | Cloning and developping of htlv-iii dna |
US5820865A (en) * | 1988-01-26 | 1998-10-13 | The United States Of America As Represented By The Department Of Health And Human Services | Method to induce cytotoxic T Lymphocytes specific for a broad array of HIV-1 isolates using hybrid synthetic peptides |
IL89567A0 (en) * | 1988-03-28 | 1989-09-10 | Univ Leland Stanford Junior | Mutated hiv envelope protein |
EP0406557B1 (en) * | 1989-05-25 | 2001-10-17 | Novartis AG | Multivalent repressor of gene function |
WO1991019011A1 (en) * | 1990-06-08 | 1991-12-12 | Repligen Corporation | Immunoassays for anti-hiv-1 antibodies |
-
1991
- 1991-10-17 DK DK91920794T patent/DK0554389T4/en active
- 1991-10-17 WO PCT/US1991/007611 patent/WO1992006990A1/en active IP Right Grant
- 1991-10-17 EP EP91920794A patent/EP0554389B2/en not_active Expired - Lifetime
- 1991-10-17 CA CA002093427A patent/CA2093427C/en not_active Expired - Lifetime
- 1991-10-17 AU AU89363/91A patent/AU649502B2/en not_active Expired
- 1991-10-17 AT AT91920794T patent/ATE163676T1/en not_active IP Right Cessation
- 1991-10-17 DE DE69129034T patent/DE69129034T3/en not_active Expired - Lifetime
- 1991-10-17 ES ES91920794T patent/ES2115622T5/en not_active Expired - Lifetime
- 1991-10-17 JP JP3518591A patent/JP2767078B2/en not_active Expired - Lifetime
-
1993
- 1993-02-25 US US08/022,835 patent/US5420030A/en not_active Expired - Lifetime
-
1995
- 1995-02-15 US US08/388,809 patent/US5576000A/en not_active Expired - Lifetime
-
1996
- 1996-05-14 US US08/647,714 patent/US5869313A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2093427A1 (en) | 1992-04-18 |
DK0554389T3 (en) | 1998-12-07 |
US5420030A (en) | 1995-05-30 |
ES2115622T5 (en) | 2003-03-16 |
JPH05507205A (en) | 1993-10-21 |
DE69129034D1 (en) | 1998-04-09 |
AU649502B2 (en) | 1994-05-26 |
EP0554389B2 (en) | 2002-08-14 |
US5576000A (en) | 1996-11-19 |
DK0554389T4 (en) | 2002-11-11 |
EP0554389A4 (en) | 1994-07-06 |
WO1992006990A1 (en) | 1992-04-30 |
DE69129034T3 (en) | 2003-05-08 |
US5869313A (en) | 1999-02-09 |
EP0554389B1 (en) | 1998-03-04 |
JP2767078B2 (en) | 1998-06-18 |
EP0554389A1 (en) | 1993-08-11 |
CA2093427C (en) | 2008-01-15 |
AU8936391A (en) | 1992-05-20 |
ES2115622T3 (en) | 1998-07-01 |
DE69129034T2 (en) | 1998-10-08 |
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Legal Events
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