ATE155461T1 - Verbessertes verfahren zur herstellung von 4- halogenchinazoline - Google Patents

Verbessertes verfahren zur herstellung von 4- halogenchinazoline

Info

Publication number
ATE155461T1
ATE155461T1 AT92117058T AT92117058T ATE155461T1 AT E155461 T1 ATE155461 T1 AT E155461T1 AT 92117058 T AT92117058 T AT 92117058T AT 92117058 T AT92117058 T AT 92117058T AT E155461 T1 ATE155461 T1 AT E155461T1
Authority
AT
Austria
Prior art keywords
halogenquinazolines
producing
improved process
haloquinazolines
hydroxyquinazolines
Prior art date
Application number
AT92117058T
Other languages
English (en)
Inventor
Jimmy J Tai
James W Ringer
Karl L Krumel
Richard C Krauss
Original Assignee
Dowelanco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dowelanco filed Critical Dowelanco
Application granted granted Critical
Publication of ATE155461T1 publication Critical patent/ATE155461T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT92117058T 1991-10-07 1992-10-06 Verbessertes verfahren zur herstellung von 4- halogenchinazoline ATE155461T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/772,523 US5214144A (en) 1991-10-07 1991-10-07 Process for the preparation of 4-haloquinazolines

Publications (1)

Publication Number Publication Date
ATE155461T1 true ATE155461T1 (de) 1997-08-15

Family

ID=25095358

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92117058T ATE155461T1 (de) 1991-10-07 1992-10-06 Verbessertes verfahren zur herstellung von 4- halogenchinazoline

Country Status (11)

Country Link
US (1) US5214144A (de)
EP (1) EP0537600B1 (de)
JP (1) JPH05222004A (de)
KR (1) KR100218608B1 (de)
AT (1) ATE155461T1 (de)
AU (1) AU648933B2 (de)
BR (1) BR9203883A (de)
DE (1) DE69220875T2 (de)
ES (1) ES2104787T3 (de)
HU (1) HU213830B (de)
IL (1) IL103362A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747498A (en) 1996-05-28 1998-05-05 Pfizer Inc. Alkynyl and azido-substituted 4-anilinoquinazolines
AU727200B2 (en) * 1996-03-15 2000-12-07 Dow Agrosciences Llc Halogenation catalyst
US6706721B1 (en) * 1998-04-29 2004-03-16 Osi Pharmaceuticals, Inc. N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
US7087613B2 (en) * 1999-11-11 2006-08-08 Osi Pharmaceuticals, Inc. Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
UA74803C2 (uk) 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
CN103265497B (zh) * 2013-05-16 2014-11-26 苏州明锐医药科技有限公司 一种替尼类抗肿瘤药合成所需中间体4-氯-6-氨基-7-羟基喹唑啉及其制备方法
CN106496146A (zh) * 2016-10-18 2017-03-15 江西师范大学 一种二氢喹唑啉酮和喹唑啉酮衍生物的磺酸类离子液体催化调控合成方法
CN108299315A (zh) * 2018-03-01 2018-07-20 杨子辉 一种杀螨剂喹螨醚的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1880447A (en) * 1932-10-04 Max haedtmann
US450870A (en) * 1891-04-21 Bag-fastening
GB1088102A (en) * 1964-01-10 1967-10-25 Wellcome Found Halogen substituted pyrido-pyrimidines
US3998951A (en) * 1974-03-13 1976-12-21 Fmc Corporation Substituted 2-arylquinazolines as fungicides
US4510307A (en) * 1980-08-20 1985-04-09 Asahi Kasei Kogyo Kabushiki Kaisha 6-Quinazolinesulfonyl derivatives and process for preparation thereof
US4672116A (en) * 1985-12-20 1987-06-09 Ortho Pharmaceutical Corporation Substituted 5,6-dialkoxyquinazoline derivatives
IL89027A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Quinazoline derivatives, process for their preparation and fungicidal, insecticidal and miticidal compositions containing them

Also Published As

Publication number Publication date
HU213830B (en) 1997-10-28
IL103362A0 (en) 1993-03-15
HU9203164D0 (en) 1992-12-28
ES2104787T3 (es) 1997-10-16
KR930007916A (ko) 1993-05-20
JPH05222004A (ja) 1993-08-31
IL103362A (en) 1996-09-12
KR100218608B1 (ko) 1999-09-01
EP0537600B1 (de) 1997-07-16
BR9203883A (pt) 1993-04-27
DE69220875T2 (de) 1997-11-20
AU2623992A (en) 1993-04-08
US5214144A (en) 1993-05-25
AU648933B2 (en) 1994-05-05
EP0537600A1 (de) 1993-04-21
HUT62868A (en) 1993-06-28
DE69220875D1 (de) 1997-08-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner