ATE154612T1 - Therapeutische somatostatin-analoge - Google Patents

Therapeutische somatostatin-analoge

Info

Publication number
ATE154612T1
ATE154612T1 AT87310487T AT87310487T ATE154612T1 AT E154612 T1 ATE154612 T1 AT E154612T1 AT 87310487 T AT87310487 T AT 87310487T AT 87310487 T AT87310487 T AT 87310487T AT E154612 T1 ATE154612 T1 AT E154612T1
Authority
AT
Austria
Prior art keywords
trp
somatostatin analogue
nal
cys
thr
Prior art date
Application number
AT87310487T
Other languages
English (en)
Inventor
David H Coy
William A Murphy
Mark L Heiman
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Application granted granted Critical
Publication of ATE154612T1 publication Critical patent/ATE154612T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT87310487T 1987-02-03 1987-11-27 Therapeutische somatostatin-analoge ATE154612T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1034987A 1987-02-03 1987-02-03

Publications (1)

Publication Number Publication Date
ATE154612T1 true ATE154612T1 (de) 1997-07-15

Family

ID=21745328

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87310487T ATE154612T1 (de) 1987-02-03 1987-11-27 Therapeutische somatostatin-analoge

Country Status (6)

Country Link
EP (1) EP0277419B1 (de)
JP (1) JP2568228B2 (de)
AT (1) ATE154612T1 (de)
DE (1) DE3752082T2 (de)
ES (1) ES2104551T3 (de)
GR (1) GR3024570T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU217636B (hu) * 1989-04-26 2000-03-28 Administrators Of The Tulane Educational Fund Szomatosztatin analógok, ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
HUT59166A (en) * 1989-12-08 1992-04-28 Univ Tulane Process for producing octqpeptide somatostatine analogues with treonine at the 6 position and pharmaceutical compositions containing them
HU207104B (en) * 1991-01-25 1993-03-01 Biosignal Kutato Fejlesztoe Kf Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
CA2072048A1 (en) * 1991-06-28 1992-12-29 Jackson B. Gibbs Non-substrate inhibitors of farnesyl protein transferase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328135A (en) * 1980-06-13 1982-05-04 American Home Products Corporation Octapeptides lowering growth hormone
US4440904A (en) * 1983-01-31 1984-04-03 American Home Products Corporation Nonapeptide anti-secretory agents
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
JPH085913B2 (ja) * 1985-09-12 1996-01-24 ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド 治療用ソマトスタチン同族体

Also Published As

Publication number Publication date
JPS63196599A (ja) 1988-08-15
EP0277419A3 (de) 1990-02-14
JP2568228B2 (ja) 1996-12-25
DE3752082T2 (de) 1998-01-29
EP0277419B1 (de) 1997-06-18
ES2104551T3 (es) 1997-10-16
EP0277419A2 (de) 1988-08-10
DE3752082D1 (de) 1997-07-24
GR3024570T3 (en) 1997-12-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee