ATE153024T1 - Azabicyclische verbindungen - Google Patents

Azabicyclische verbindungen

Info

Publication number
ATE153024T1
ATE153024T1 AT90308899T AT90308899T ATE153024T1 AT E153024 T1 ATE153024 T1 AT E153024T1 AT 90308899 T AT90308899 T AT 90308899T AT 90308899 T AT90308899 T AT 90308899T AT E153024 T1 ATE153024 T1 AT E153024T1
Authority
AT
Austria
Prior art keywords
group
alkyl
hydrogen
nitrogen
sulphur
Prior art date
Application number
AT90308899T
Other languages
English (en)
Inventor
Paul Adrian Wyman
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898918659A external-priority patent/GB8918659D0/en
Priority claimed from GB898918658A external-priority patent/GB8918658D0/en
Priority claimed from GB909004437A external-priority patent/GB9004437D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Application granted granted Critical
Publication of ATE153024T1 publication Critical patent/ATE153024T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT90308899T 1989-08-16 1990-08-13 Azabicyclische verbindungen ATE153024T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898918659A GB8918659D0 (en) 1989-08-16 1989-08-16 Novel compounds
GB898918658A GB8918658D0 (en) 1989-08-16 1989-08-16 Novel compounds
GB909004437A GB9004437D0 (en) 1990-02-28 1990-02-28 Novel compounds

Publications (1)

Publication Number Publication Date
ATE153024T1 true ATE153024T1 (de) 1997-05-15

Family

ID=27264638

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90308899T ATE153024T1 (de) 1989-08-16 1990-08-13 Azabicyclische verbindungen

Country Status (9)

Country Link
US (1) US5043343A (de)
EP (1) EP0413545B1 (de)
JP (1) JP2976128B2 (de)
KR (1) KR910004608A (de)
AT (1) ATE153024T1 (de)
AU (1) AU627612B2 (de)
DE (1) DE69030695T2 (de)
IE (1) IE902943A1 (de)
NZ (1) NZ234903A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
GB8717446D0 (en) * 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
US5908891A (en) * 1996-04-19 1999-06-01 Dow Corning Corporation Dispersible silicone compositions
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
WO2012033956A1 (en) 2010-09-08 2012-03-15 Mithridion, Inc. Cognition enhancing compounds and compositions, methods of making, and methods of treating

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
NZ224237A (en) * 1987-04-15 1991-04-26 Beecham Group Plc Bicyclic compounds (n bridged compounds)
ES2053748T3 (es) * 1987-09-10 1994-08-01 Merck Sharp & Dohme Oxazoles y tiazoles para el tratamiento de la demencia senil.
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0322182A3 (de) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclische-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
IL88846A0 (en) * 1988-01-08 1989-07-31 Merck Sharp & Dohme Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
GB8808926D0 (en) * 1988-04-15 1988-05-18 Beecham Group Plc Novel compounds
US5110828A (en) * 1988-04-15 1992-05-05 Beecham Group P.L.C. Azabicyclo oxime derivatives
CA2000041A1 (en) * 1988-10-13 1990-04-13 Barry S. Orlek Compounds
GB8911080D0 (en) * 1989-05-15 1989-06-28 Merck Sharp & Dohme Chemical process
EP0398617A3 (de) * 1989-05-15 1991-11-06 Merck Sharp & Dohme Ltd. Verfahren zur optischen Spaltung von 1-Azabicyclo[2.2.1]heptan-3-carbonsäure
EP0402056A3 (de) * 1989-06-06 1991-09-04 Beecham Group p.l.c. Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Also Published As

Publication number Publication date
JPH0386883A (ja) 1991-04-11
EP0413545B1 (de) 1997-05-14
IE902943A1 (en) 1991-02-27
NZ234903A (en) 1993-01-27
DE69030695T2 (de) 1998-01-08
EP0413545A2 (de) 1991-02-20
EP0413545A3 (en) 1991-11-06
DE69030695D1 (de) 1997-06-19
KR910004608A (ko) 1991-03-29
AU627612B2 (en) 1992-08-27
JP2976128B2 (ja) 1999-11-10
US5043343A (en) 1991-08-27
AU6100390A (en) 1991-02-21

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties