ATE147757T1 - Propanolamin-cyclohexapeptide - Google Patents

Propanolamin-cyclohexapeptide

Info

Publication number
ATE147757T1
ATE147757T1 AT92308974T AT92308974T ATE147757T1 AT E147757 T1 ATE147757 T1 AT E147757T1 AT 92308974 T AT92308974 T AT 92308974T AT 92308974 T AT92308974 T AT 92308974T AT E147757 T1 ATE147757 T1 AT E147757T1
Authority
AT
Austria
Prior art keywords
propanolamine
cyclohexapeptides
cyclohexapeptidyl
nucleus
found
Prior art date
Application number
AT92308974T
Other languages
English (en)
Inventor
Milton L Hammond
Robert A Zambias
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE147757T1 publication Critical patent/ATE147757T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92308974T 1991-10-01 1992-10-01 Propanolamin-cyclohexapeptide ATE147757T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77101791A 1991-10-01 1991-10-01
US07/936,561 US5939384A (en) 1991-10-01 1992-09-03 Cyclohexapeptidyl propanolamine compounds

Publications (1)

Publication Number Publication Date
ATE147757T1 true ATE147757T1 (de) 1997-02-15

Family

ID=27118384

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92308974T ATE147757T1 (de) 1991-10-01 1992-10-01 Propanolamin-cyclohexapeptide

Country Status (9)

Country Link
US (1) US5939384A (de)
EP (1) EP0535959B1 (de)
JP (1) JPH07121958B2 (de)
AT (1) ATE147757T1 (de)
CA (1) CA2079171C (de)
DE (1) DE69216746T2 (de)
DK (1) DK0535959T3 (de)
ES (1) ES2098455T3 (de)
GR (1) GR3022292T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
AR006598A1 (es) * 1996-04-19 1999-09-08 Merck Sharp & Dohme "composiciones anti-fungosas, su uso en la manufactura de medicamentos y un procedimiento para su preparación"
WO1999055727A1 (en) * 1998-04-23 1999-11-04 Aventis Pharma Deutschland Gmbh A process for the conversion of echinocandin class of peptides to their c4-homotyrosine monodeoxy analogues
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
TWI250992B (en) 2000-02-21 2006-03-11 Astellas Pharma Inc Polypeptide compounds for the prophylactic and/or therapeutic treatment of infectious diseases caused by pathogenic microorganisms
AUPR234400A0 (en) * 2000-12-28 2001-01-25 Fujisawa Pharmaceutical Co., Ltd. New compound
AR035808A1 (es) * 2001-04-12 2004-07-14 Merck & Co Inc Proceso de deshidratacion capaz de minimizar la epimerizacion de un grupo hidroxilo por ciertas equinocandinas
US7214768B2 (en) * 2002-04-08 2007-05-08 Merck & Co., Inc. Echinocandin process
US8048853B2 (en) 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
EP3620462A1 (de) 2018-09-04 2020-03-11 Xellia Pharmaceuticals ApS Verfahren zur herstellung von caspofungin

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173629A (en) * 1975-07-08 1979-11-06 Sandoz Ltd. Antibiotic S 31794/F-1
BE851310A (fr) * 1976-02-12 1977-08-10 Sandoz Sa Nouveaux derives de la tetrahydro-equinocandine b
DE2742435A1 (de) * 1976-09-28 1978-04-06 Sandoz Ag Aminoalkylaether der peptide tetrahydro- sl 7810/f-ii, s 31794/f-1, aculeacin a und tetrahydroechinocandin b, ihre verwendung und herstellung
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4320054A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912H nucleus
US4293485A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4287120A (en) * 1979-12-13 1981-09-01 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4931352A (en) * 1987-10-07 1990-06-05 Merck & Co., Inc. Antifungal fermentation product
US4968608A (en) * 1987-10-07 1990-11-06 Merck & Co., Inc. Process for antifungal fermentation product
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
US5021341A (en) * 1990-03-12 1991-06-04 Merck & Co., Inc. Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
US5310873A (en) * 1990-03-12 1994-05-10 Merck & Co., Inc. Cyclohexapeptide compound
US5021403A (en) * 1990-03-19 1991-06-04 Merck & Co., Inc. Antibiotic agents
US5159059A (en) * 1990-05-29 1992-10-27 Merck & Co., Inc. Process for reduction of certain cyclohexapeptide compounds
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii

Also Published As

Publication number Publication date
DE69216746T2 (de) 1997-07-03
JPH07121958B2 (ja) 1995-12-25
ES2098455T3 (es) 1997-05-01
EP0535959B1 (de) 1997-01-15
CA2079171C (en) 2000-10-03
CA2079171A1 (en) 1993-04-02
GR3022292T3 (en) 1997-04-30
US5939384A (en) 1999-08-17
JPH06234795A (ja) 1994-08-23
DK0535959T3 (da) 1997-06-09
DE69216746D1 (de) 1997-02-27
EP0535959A1 (de) 1993-04-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee