ATE142501T1 - Verwendung von 1-(beta-d-arabinofuranosyl)-5- propynyluracil zur senkung des serumcholesterins - Google Patents

Verwendung von 1-(beta-d-arabinofuranosyl)-5- propynyluracil zur senkung des serumcholesterins

Info

Publication number
ATE142501T1
ATE142501T1 AT92910638T AT92910638T ATE142501T1 AT E142501 T1 ATE142501 T1 AT E142501T1 AT 92910638 T AT92910638 T AT 92910638T AT 92910638 T AT92910638 T AT 92910638T AT E142501 T1 ATE142501 T1 AT E142501T1
Authority
AT
Austria
Prior art keywords
pct
propynyluracil
arabinofuranosyl
beta
serum cholesterol
Prior art date
Application number
AT92910638T
Other languages
English (en)
Inventor
Richard Wilson Peck
John Posner
Kenneth Powell
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE142501T1 publication Critical patent/ATE142501T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT92910638T 1991-05-30 1992-05-29 Verwendung von 1-(beta-d-arabinofuranosyl)-5- propynyluracil zur senkung des serumcholesterins ATE142501T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919111580A GB9111580D0 (en) 1991-05-30 1991-05-30 Nucleoside derivative

Publications (1)

Publication Number Publication Date
ATE142501T1 true ATE142501T1 (de) 1996-09-15

Family

ID=10695778

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92910638T ATE142501T1 (de) 1991-05-30 1992-05-29 Verwendung von 1-(beta-d-arabinofuranosyl)-5- propynyluracil zur senkung des serumcholesterins

Country Status (14)

Country Link
US (1) US5432166A (de)
EP (1) EP0542952B1 (de)
JP (1) JPH06500129A (de)
AT (1) ATE142501T1 (de)
AU (1) AU657756B2 (de)
CA (1) CA2088264A1 (de)
DE (1) DE69213660D1 (de)
GB (1) GB9111580D0 (de)
HU (1) HUT63767A (de)
IE (1) IE921731A1 (de)
IL (1) IL102058A (de)
MX (1) MX9202595A (de)
WO (1) WO1992021352A1 (de)
ZA (1) ZA923962B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US20030054042A1 (en) * 2001-09-14 2003-03-20 Elaine Liversidge Stabilization of chemical compounds using nanoparticulate formulations
JP4842514B2 (ja) * 2002-03-20 2011-12-21 エラン ファーマ インターナショナル,リミティド 血管新生抑制剤のナノ粒子組成物
DK2794627T3 (en) 2011-12-22 2019-01-14 Alios Biopharma Inc SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGUES THEREOF
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2244328A1 (de) * 1972-09-09 1974-03-21 Boehringer Mannheim Gmbh Neue n(6)-disubstituierte adenosinderivate und verfahren zur herstellung derselben
US4594339A (en) * 1982-04-06 1986-06-10 Sloan-Kettering Institute For Cancer Research Anti-herpes virus compositions containing 5-substituted 1-2'(deoxy-2-'-substituted-β-d-arabinofuranosyl)pyrimedene nucleosides
IT1196261B (it) * 1984-09-20 1988-11-16 Pierrel Spa Derivati nucleosidici e purinici 8-sostituiti
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
GB8629892D0 (en) * 1986-12-15 1987-01-28 Wellcome Found Antiviral compounds
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida
US4962194A (en) * 1987-04-02 1990-10-09 Warner-Lambert Company Method of preparing 51,N6-disubstituted adenosines from inosines
US5028596A (en) * 1987-12-14 1991-07-02 Burroughs Wellcome Co. 1-(β-D-arabinofuranosyl)-5-propynyluracil for treatment of VZV infections
GB8729994D0 (en) * 1987-12-23 1988-02-03 Glaxo Group Ltd Chemical compounds
AU3820989A (en) * 1988-08-02 1990-02-08 Ciba-Geigy Ag 7-amino-3-beta-d-ribofuranosyl-3h-imidazo(4,5-b) pyridin-5-amine derivatives
GB2226027B (en) * 1988-12-13 1992-05-20 Sandoz Ltd Adenosine derivatives,their production and use
JPH03287537A (ja) * 1990-03-31 1991-12-18 Yamasa Shoyu Co Ltd 抗動脈硬化症剤
FR2665362B1 (fr) * 1990-08-03 1994-12-09 Cepbepe Substance contenant, comme principe actif, une adenosine substitutee en n6 et son application.

Also Published As

Publication number Publication date
AU1767392A (en) 1993-01-08
US5432166A (en) 1995-07-11
AU657756B2 (en) 1995-03-23
EP0542952B1 (de) 1996-09-11
IE921731A1 (en) 1992-12-02
JPH06500129A (ja) 1994-01-06
IL102058A0 (en) 1992-12-30
EP0542952A1 (de) 1993-05-26
HUT63767A (en) 1993-10-28
MX9202595A (es) 1992-11-01
IL102058A (en) 1996-07-23
CA2088264A1 (en) 1992-12-01
DE69213660D1 (de) 1996-10-17
GB9111580D0 (en) 1991-07-24
WO1992021352A1 (en) 1992-12-10
HU9300243D0 (en) 1993-04-28
ZA923962B (en) 1993-11-29

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Legal Events

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