ATE123290T1 - Herstellung und charakterisierung der liposomformulierungen des tumornekrosefaktors. - Google Patents

Herstellung und charakterisierung der liposomformulierungen des tumornekrosefaktors.

Info

Publication number
ATE123290T1
ATE123290T1 AT91920548T AT91920548T ATE123290T1 AT E123290 T1 ATE123290 T1 AT E123290T1 AT 91920548 T AT91920548 T AT 91920548T AT 91920548 T AT91920548 T AT 91920548T AT E123290 T1 ATE123290 T1 AT E123290T1
Authority
AT
Austria
Prior art keywords
tnf
modified
necrosis factor
tumor necrosis
liposomes
Prior art date
Application number
AT91920548T
Other languages
English (en)
Inventor
Mien-Chie Hung
Toshihiko Utsumi
Jim Klostergaard
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE123290T1 publication Critical patent/ATE123290T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91920548T 1990-10-18 1991-10-16 Herstellung und charakterisierung der liposomformulierungen des tumornekrosefaktors. ATE123290T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59981190A 1990-10-18 1990-10-18

Publications (1)

Publication Number Publication Date
ATE123290T1 true ATE123290T1 (de) 1995-06-15

Family

ID=24401193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91920548T ATE123290T1 (de) 1990-10-18 1991-10-16 Herstellung und charakterisierung der liposomformulierungen des tumornekrosefaktors.

Country Status (7)

Country Link
EP (1) EP0553281B1 (de)
JP (1) JPH06501702A (de)
AT (1) ATE123290T1 (de)
AU (1) AU9029591A (de)
CA (1) CA2091771A1 (de)
DE (1) DE69110133T2 (de)
WO (1) WO1992006995A1 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283046C (en) * 1986-05-29 1991-04-16 Nandini Katre Tumor necrosis factor formulation
DE3936777A1 (de) * 1989-11-04 1991-05-08 Basf Ag Quervernetzte tumor-nekrose-faktoren

Also Published As

Publication number Publication date
EP0553281B1 (de) 1995-05-31
AU9029591A (en) 1992-05-20
DE69110133T2 (de) 1996-02-15
JPH06501702A (ja) 1994-02-24
DE69110133D1 (de) 1995-07-06
WO1992006995A1 (en) 1992-04-30
EP0553281A1 (de) 1993-08-04
CA2091771A1 (en) 1992-04-19

Similar Documents

Publication Publication Date Title
ES2194114T3 (es) Formulaciones liposomicas de mitoxantrona.
FI971776A0 (fi) Yhdisteet ja koostumukset aktiivisten aineiden antamiseksi
BR9808881A (pt) Compostos para imunoterapia de câncer de próstata e métodos para seu uso
HK1007497A1 (en) Accumulations of amino acids and peptides into liposomes
HK1005224A1 (en) Use of complex lipide as stabilizing additives in pharmaceutical formulation of digestive enzyme mixture.
HK1056557A1 (en) Transesterification process for preparation of synthetic chlorophyll and bacteriochlorophyll derivative
DK1151102T3 (da) Glycosylerede leptinpræparater og relaterede fremgangsmåder
FI940375A0 (fi) Peptidit, joilla on elimiä suojaavaa vaikutusta, menetelmä niiden valmistamiseksi ja niiden käyttö terapiassa
FI20075338A (fi) gb350/220:n ei silmukoivia muutoksia
GB2302505A (en) Stabilisation of photosensitive materials
WO2001019852A8 (en) Methods of peptide preparation
FI101597B1 (fi) Menetelmä kylmäkuivatun koostumuksen valmistamiseksi käytettäväksi potilaan valodynaamisessa hoidossa tai diagnosoinnissa
ATE123290T1 (de) Herstellung und charakterisierung der liposomformulierungen des tumornekrosefaktors.
AU624079B2 (en) Novel fluorinated derivatives of amino acids usable more particularly as surfactants or cosurfactants and preparations for biomedical use incorporating these derivatives
AU676464B2 (en) Proteolytic mixture containing escharase and method of isolating same
ITMI912837A1 (it) Procedimento per preparare prodotti peptidici e/o proteinici arricchiti con amminoacidi legati in modo covalente
TH39537EX (th) กรรมวิธีใหม่สำหรับเตรียมเพพไทด์ที่ถูกไลโอฟิไลซ์
AR010817A1 (es) Crema de belleza antiarrugas y proceso para la preparacion
AR010816A1 (es) Crema para borrar cicatrices (estrias) en los fibroplastos de la dermis profunda y proceso para la preparacion
AR010812A1 (es) Crema de belleza integral, nutriente, suavizante y quitamanchas solares y proceso para la preparacion
ZA977308B (en) Use of complex lipids as stabilizing-additives to pharmaceutical preparations of digestive enzyme mixtures.