ATE122704T1 - Magnetisierbare mikrokugeln aus vernetztem, hydrophobem polymer, verfahren zu ihrer herstellung und ihre verwendung in der biologie. - Google Patents

Magnetisierbare mikrokugeln aus vernetztem, hydrophobem polymer, verfahren zu ihrer herstellung und ihre verwendung in der biologie.

Info

Publication number
ATE122704T1
ATE122704T1 AT90400705T AT90400705T ATE122704T1 AT E122704 T1 ATE122704 T1 AT E122704T1 AT 90400705 T AT90400705 T AT 90400705T AT 90400705 T AT90400705 T AT 90400705T AT E122704 T1 ATE122704 T1 AT E122704T1
Authority
AT
Austria
Prior art keywords
biology
microblades
magnetizable
production
cross
Prior art date
Application number
AT90400705T
Other languages
German (de)
English (en)
Inventor
Dominique Charmot
Christine Vidil
Original Assignee
Prolabo Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prolabo Sa filed Critical Prolabo Sa
Application granted granted Critical
Publication of ATE122704T1 publication Critical patent/ATE122704T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/5434Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F292/00Macromolecular compounds obtained by polymerising monomers on to inorganic materials
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K9/00Use of pretreated ingredients
    • C08K9/10Encapsulated ingredients
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/20Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/30Magnetic particle immunoreagent carriers the magnetic material being dispersed in the polymer composition before their conversion into particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/60Magnetic particle immunoreagent carriers the magnetic material being dispersed in a medium other than the main solvent prior to incorporation into the polymer particle
    • G01N2446/64Magnetic material dispersed in oil drop
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/60Magnetic particle immunoreagent carriers the magnetic material being dispersed in a medium other than the main solvent prior to incorporation into the polymer particle
    • G01N2446/66Magnetic material dispersed in surfactant
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/80Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/84Polymer coating, e.g. gelatin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2998Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Materials Engineering (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Soft Magnetic Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polymerisation Methods In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Compounds Of Iron (AREA)
  • Materials For Medical Uses (AREA)
  • Powder Metallurgy (AREA)
  • Hard Magnetic Materials (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
AT90400705T 1989-03-31 1990-03-16 Magnetisierbare mikrokugeln aus vernetztem, hydrophobem polymer, verfahren zu ihrer herstellung und ihre verwendung in der biologie. ATE122704T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8904231A FR2645160B1 (US06171609-20010109-C00004.png) 1989-03-31 1989-03-31

Publications (1)

Publication Number Publication Date
ATE122704T1 true ATE122704T1 (de) 1995-06-15

Family

ID=9380242

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90400705T ATE122704T1 (de) 1989-03-31 1990-03-16 Magnetisierbare mikrokugeln aus vernetztem, hydrophobem polymer, verfahren zu ihrer herstellung und ihre verwendung in der biologie.

Country Status (12)

Country Link
US (1) US5356713A (US06171609-20010109-C00004.png)
EP (1) EP0390634B1 (US06171609-20010109-C00004.png)
JP (1) JP2623358B2 (US06171609-20010109-C00004.png)
AT (1) ATE122704T1 (US06171609-20010109-C00004.png)
AU (1) AU5239690A (US06171609-20010109-C00004.png)
CA (1) CA2013459A1 (US06171609-20010109-C00004.png)
DE (1) DE69019411T2 (US06171609-20010109-C00004.png)
ES (1) ES2072996T3 (US06171609-20010109-C00004.png)
FI (1) FI901628A0 (US06171609-20010109-C00004.png)
FR (1) FR2645160B1 (US06171609-20010109-C00004.png)
IL (1) IL93947A0 (US06171609-20010109-C00004.png)
NO (1) NO178376C (US06171609-20010109-C00004.png)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272216A (en) * 1990-12-28 1993-12-21 Westinghouse Electric Corp. System and method for remotely heating a polymeric material to a selected temperature
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) * 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5595722A (en) * 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US6663881B2 (en) * 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
WO1994026303A1 (en) 1993-05-13 1994-11-24 Neorx Corporation Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
US5628407A (en) * 1994-12-05 1997-05-13 Bolt Beranek And Newman, Inc. Method and apparatus for separation of magnetically responsive spheres
US5684130A (en) * 1995-06-05 1997-11-04 Solid Phase Sciences Corporation Process for synthesis of organic compounds using magnetic particles
ATE377418T1 (de) 1995-06-07 2007-11-15 Poniard Pharmaceuticals Inc Vorbeugung und behandlung von kardiovaskulären beschwerden mit tamoxifen-analogen
FR2735778B1 (fr) * 1995-06-22 1997-08-22 Prolabo Sa Nouveau latex de microspheres magnetisables monodisperses calibrees, procede de preparation et utilisation dudit latex en chimie ou en biologie
US5834121A (en) * 1996-01-16 1998-11-10 Solid Phase Sciences Corp. Composite magnetic beads
ATE366418T1 (de) 1996-04-25 2007-07-15 Bioarray Solutions Ltd Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
DE59707683D1 (de) * 1996-11-28 2002-08-14 Fludicon Gmbh Magnetorheologische Flüssigkeiten und mit Polymer beschichtete, magnetische Teilchen
FR2758884B1 (fr) 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
FR2773416B1 (fr) * 1998-01-06 2000-02-11 Bio Merieux Particules magnetiques perfectionnees, leurs procedes d'obtention et leurs utilisations dans la separation de molecules
US6423410B1 (en) 1998-09-04 2002-07-23 Mds Proteomics, Inc. Ultrasonically generated paramagnetic polymer particles
CN1105741C (zh) * 1998-11-10 2003-04-16 中国科学院化工冶金研究所 超顺磁性聚合物微球及其制造方法
FR2800635B1 (fr) * 1999-11-05 2002-07-26 Bio Merieux Nanospheres composites, conjugues derives, procede de preparation et leurs utilisations
FR2800636A1 (fr) * 1999-11-05 2001-05-11 Bio Merieux Particules composites, conjugues derives, leur procede de preparation et utilisations
AU4989501A (en) * 2000-04-06 2001-10-23 Luminex Corp Magnetically-responsive microspheres
AU2001261463A1 (en) * 2000-05-12 2001-11-26 University Of Cincinnati Magnetic bead-based arrays
DE60117556T2 (de) 2000-06-21 2006-11-02 Bioarray Solutions Ltd. Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
US9709559B2 (en) * 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
DE10033583A1 (de) 2000-07-11 2002-01-24 Bayer Ag Superparamagnetische Perlpolymerisate
FR2824563B1 (fr) * 2001-05-10 2004-12-03 Bio Merieux Particules composites, conjugues derives, procede de preparation et applications
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US7169577B2 (en) 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7285412B2 (en) 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
US7169578B2 (en) 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US20040002073A1 (en) 2001-10-15 2004-01-01 Li Alice Xiang Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US7255895B2 (en) * 2003-01-21 2007-08-14 Bioarray Solutions, Ltd. Method for controlling solute loading of polymer microparticles
US6964747B2 (en) * 2003-01-21 2005-11-15 Bioarray Solutions, Ltd. Production of dyed polymer microparticles
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
PT1664722E (pt) 2003-09-22 2011-12-28 Bioarray Solutions Ltd Polielectrólito imobilizado à superfície com grupos funcionais múltiplos capazes de se ligarem covalentemente às biomoléculas
US7563569B2 (en) 2003-10-28 2009-07-21 Michael Seul Optimization of gene expression analysis using immobilized capture probes
ES2533876T3 (es) 2003-10-29 2015-04-15 Bioarray Solutions Ltd Análisis multiplexado de ácidos nucleicos mediante fragmentación de ADN bicatenario
US20050106577A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Cleavable solid phases for isolating nucleic acids
US20050106576A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Methods of using cleavable solid phases for isolating nucleic acids
MXPA06010789A (es) * 2004-03-23 2007-05-15 Commw Scient Ind Res Org Esferas de polimero que incorporan particulas de oxido de hierro.
US8563212B2 (en) * 2004-07-16 2013-10-22 Transitions Optical, Inc. Methods for producing photosensitive microparticles, non-aqueous dispersions thereof and articles prepared therewith
US8153344B2 (en) * 2004-07-16 2012-04-10 Ppg Industries Ohio, Inc. Methods for producing photosensitive microparticles, aqueous compositions thereof and articles prepared therewith
US8563213B2 (en) * 2004-07-16 2013-10-22 Transitions Optical, Inc. Methods for producing photosensitive microparticles
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP4811565B2 (ja) * 2005-03-31 2011-11-09 Jsr株式会社 多孔質表面を有する磁性粒子およびその製造方法、生化学用担体、ならびにビオチン類結合用粒子
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
FR2894970B1 (fr) * 2005-12-15 2008-01-25 Biomerieux Sa Procede de preparation de particules composites, particules composites obtenues et leur utilisation dans un test diagnostic
EP2000484B1 (en) * 2006-03-27 2011-11-30 Tokyo Institute of Technology Process for producing polymer-coated ferromagnetic particle, and polymer-coated ferromagnetic particle
TWI322793B (en) * 2006-10-02 2010-04-01 Chung Cheng Inst Of Technology Nat Defense University Functionalized magnetizable microspheres and preparation thereof
US7981688B2 (en) * 2007-03-08 2011-07-19 University Of Washington Stimuli-responsive magnetic nanoparticles and related methods
US8426214B2 (en) * 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
US20110117668A1 (en) * 2009-11-09 2011-05-19 University Of Washington Through Its Center For Commercialization Self-powered smart diagnostic devices
US9080933B2 (en) 2009-11-09 2015-07-14 University Of Washington Through Its Center For Commercialization Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
WO2011127390A2 (en) 2010-04-09 2011-10-13 Luminex Corporation Magnetic separation device
WO2013083847A2 (en) 2011-12-09 2013-06-13 Institut Pasteur Multiplex immuno screening assay
WO2014134144A1 (en) 2013-02-28 2014-09-04 The General Hospital Corporation Mirna profiling compositions and methods of use
US9349535B2 (en) 2013-12-17 2016-05-24 Metastable Materials, Inc. Method and apparatus for manufacturing isotropic magnetic nanocolloids by pulsed laser ablation
CN105126714B (zh) * 2015-08-05 2020-04-14 浙江东方基因生物制品股份有限公司 一种功能性纳米颗粒复合微球及其制备与应用
EP3504550B1 (en) 2016-08-26 2021-07-21 Juno Therapeutics, Inc. Methods of enumerating particles present in a cell composition
JP7337773B2 (ja) 2017-07-29 2023-09-04 ジュノー セラピューティクス インコーポレイテッド 組換え受容体を発現している細胞を増大させるための試薬
KR20200136409A (ko) 2018-02-28 2020-12-07 주노 쎄러퓨티크스 인코퍼레이티드 세포 조성물에 존재하는 입자를 검출하는 방법
US20200041518A1 (en) 2018-08-03 2020-02-06 CellMax Life, Inc. Lipid vesicle-coated magnetic beads and uses of the same
WO2022020234A2 (en) * 2020-07-20 2022-01-27 Bio-Rad Laboratories, Inc. Immunoassay for sars-cov-2 neutralizing antibodies and materials therefor
KR20230159851A (ko) 2021-03-22 2023-11-22 주노 쎄러퓨티크스 인코퍼레이티드 치료 세포 조성물의 효력을 결정하는 방법
CA3208944A1 (en) 2021-03-22 2022-09-29 Edith NALBANDIAN Method to assess potency of viral vector particles

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3228881A (en) * 1963-01-04 1966-01-11 Chevron Res Dispersions of discrete particles of ferromagnetic metals
US3714102A (en) * 1970-12-02 1973-01-30 Gulf Oil Canada Ltd Polymer encapsulation of finely divided solids
US3843540A (en) * 1972-07-26 1974-10-22 Us Interior Production of magnetic fluids by peptization techniques
IT1145696B (it) * 1979-08-24 1986-11-05 Rhone Poulenc Ind Procedimento di preparazione di perle magnetiche di polimeri vinilaromatici
FR2480764B1 (fr) * 1980-04-18 1985-10-04 Rhone Poulenc Spec Chim Latex de polymeres magnetiques et procede de preparation
US4421660A (en) * 1980-12-15 1983-12-20 The Dow Chemical Company Colloidal size hydrophobic polymers particulate having discrete particles of an inorganic material dispersed therein
US4454234A (en) * 1981-12-30 1984-06-12 Czerlinski George H Coated magnetizable microparticles, reversible suspensions thereof, and processes relating thereto
US4695392A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
JPS59221302A (ja) * 1983-05-31 1984-12-12 Japan Synthetic Rubber Co Ltd 磁性重合体粒子の製造方法
EP0156537A3 (en) * 1984-03-02 1987-05-13 Board Of Regents University Of Texas System Biological magnetic fluids
US4680200A (en) * 1985-07-22 1987-07-14 The Dow Chemical Company Method for preparing colloidal size particulate
FR2613372B1 (fr) * 1987-04-03 1989-06-09 Rhone Poulenc Chimie Particules composites polymere/metal compactes, dispersions aqueuses desdites particules, leur procede de preparation et leur application en biologie
JPS63305149A (ja) * 1987-06-05 1988-12-13 Mitsubishi Kasei Corp 磁性を有する多孔質架橋共重合体粒子およびその製造方法
FR2618084B1 (fr) * 1987-07-15 1989-11-10 Rhone Poulenc Chimie Microspheres magnetisables a base de polysiloxane, leur procede de preparation et leur application en biologie
FR2624873B1 (fr) * 1987-12-18 1992-01-10 Rhone Poulenc Chimie Particules composites magnetisables a base d'organopolysiloxane reticule, leur procede de preparation et leur application en biologie

Also Published As

Publication number Publication date
EP0390634B1 (fr) 1995-05-17
FR2645160A1 (US06171609-20010109-C00004.png) 1990-10-05
DE69019411T2 (de) 1995-11-09
CA2013459A1 (fr) 1990-09-30
NO178376C (no) 1996-03-13
NO901440L (no) 1990-10-01
AU5239690A (en) 1990-10-04
JPH02286729A (ja) 1990-11-26
JP2623358B2 (ja) 1997-06-25
NO178376B (no) 1995-12-04
DE69019411D1 (de) 1995-06-22
IL93947A0 (en) 1990-12-23
EP0390634A1 (fr) 1990-10-03
FI901628A0 (fi) 1990-03-30
FR2645160B1 (US06171609-20010109-C00004.png) 1992-10-02
ES2072996T3 (es) 1995-08-01
NO901440D0 (no) 1990-03-29
US5356713A (en) 1994-10-18

Similar Documents

Publication Publication Date Title
ATE122704T1 (de) Magnetisierbare mikrokugeln aus vernetztem, hydrophobem polymer, verfahren zu ihrer herstellung und ihre verwendung in der biologie.
EP0324985A3 (de) Verfahren zur Herstellung von wasserabsorbierenden und wasserquellbaren Polysaccharid-Pfropfpolymeren
DE69007456D1 (de) Magnetisierbare Kern-Schale-Mikrokugeln, bestehend aus vernetztem Organopolysiloxan, Verfahren zu ihrer Herstellung und ihre Verwendung in der Biologie.
DE3686057D1 (de) Verfahren zur herstellung von polymerteilchen, diese polymerteilchen und ihre verwendung.
DE69033460D1 (de) Vernetzter polymerelektrolyt und verfahren zu seiner herstellung
DE3866341D1 (de) Teilchenfoermiges magnetisierbares verbundmaterial aus vernetztem organopolysiloxan, verfahren zu seiner herstellung und seine verwendung in der biologie.
ATE101626T1 (de) Neue copolymerisate und ihre verwendung als hilfsmittel und/oder zusatzstoff in formulierungen zur herstellung von polyisocyanat- polyadditionsprodukten.
DE294655T1 (de) Suspensionspolymerisationsverfahren zur herstellung von klebrigen elastomerpolymer-mikrokugeln, so hergestellte, klebende mikrokugel und klebebaender, die diese enthalten.
DE3770308D1 (de) Methacryl-polymer- oder copolymer-nanopartikel, verfahren zu ihrer herstellung und ihre anwendung als arzneimittelvektor.
ATE101627T1 (de) Neue copolymerisate und ihre verwendung als hilfsmittel und/oder zusatzstoff in formulierungen zur herstellung von polyisocyanat- polyadditionsprodukten.
DE3766689D1 (de) Vernetzte polymerisate und verfahren zu ihrer herstellung.
DE69007455D1 (de) Magnetisierbare Polysilsesquioxanmikrokugeln, Verfahren zu ihrer Herstellung und ihre Verwendung in der Biologie.
EP0243726A3 (en) Crosslinked vinyl polymer particles and electrographic elements and liquid developers containing such particles
DK0739961T3 (da) Dispersioner af latex med hydroxyl- og carboxylsyrefunktioner og deres anvendelse til fremstilling af coatings
YU46184B (sh) Postupak za proizvodnju poroznih sfernih polivinilhloridnih zrnaca
EP0293750A3 (de) Polymerisat-Ammoniumsalze
NO874373L (no) Nye vinylkloridharpikser og blandinger som inneholder slike harpikser.
EP0320704A3 (de) Pfropfpolymerisat-Dispersionen
JPS57182310A (en) Multi-layer structure acrylate polymer composition
EP0136439A3 (en) Acrylic polymers of intermediate molecular weight
KR980002091A (ko) 염화 비닐계 공중합체 및 자기 기록 매체
KR880002136A (ko) 자기기록매체 및 자기기록매체 제조시 유동성의 안정한 반응성 분산체를 사용하는 방법.
EP0860199A3 (en) Method of producing a membrane
Eda et al. Synthesis of Polymer Lattices With Segregated Hydrophilic Domains by Means of Seeded Copolymerization Method
JPS57180619A (en) Multi-layered structure acrylic polymer composition

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties