ATE12042T1 - AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC USE. - Google Patents

AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC USE.

Info

Publication number
ATE12042T1
ATE12042T1 AT81400621T AT81400621T ATE12042T1 AT E12042 T1 ATE12042 T1 AT E12042T1 AT 81400621 T AT81400621 T AT 81400621T AT 81400621 T AT81400621 T AT 81400621T AT E12042 T1 ATE12042 T1 AT E12042T1
Authority
AT
Austria
Prior art keywords
amino acid
acid derivatives
therapeutic use
image
antidiarrhea
Prior art date
Application number
AT81400621T
Other languages
German (de)
Inventor
Bernard Roques
Jean-Charles Schwartz
Jeanne-Marie Lecomte
Original Assignee
Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet Soc Civ filed Critical Bioprojet Soc Civ
Application granted granted Critical
Publication of ATE12042T1 publication Critical patent/ATE12042T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention relates to aminoacid derivatives, and compositions containing the same and having enkephalinase-inhibiting, antalgic, antidiarrhea and hypotensive activities, of the formula <IMAGE> whose variables are as set forth herein, for example <IMAGE>
AT81400621T 1980-04-17 1981-04-17 AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC USE. ATE12042T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8008601A FR2480747A1 (en) 1980-04-17 1980-04-17 AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
EP81400621A EP0038758B1 (en) 1980-04-17 1981-04-17 Amino-acids derivatives and their therapeutic use

Publications (1)

Publication Number Publication Date
ATE12042T1 true ATE12042T1 (en) 1985-03-15

Family

ID=9240999

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81400621T ATE12042T1 (en) 1980-04-17 1981-04-17 AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC USE.

Country Status (5)

Country Link
US (1) US4513009A (en)
EP (1) EP0038758B1 (en)
AT (1) ATE12042T1 (en)
DE (1) DE3169160D1 (en)
FR (1) FR2480747A1 (en)

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FR2480747A1 (en) 1981-10-23
US4513009A (en) 1985-04-23
DE3169160D1 (en) 1985-04-11
EP0038758B1 (en) 1985-03-06
EP0038758A1 (en) 1981-10-28

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