ATE119912T1 - Verfahren zur herstellung von 21-brom-4-pregnen- 3,20-dion-derivaten. - Google Patents

Verfahren zur herstellung von 21-brom-4-pregnen- 3,20-dion-derivaten.

Info

Publication number
ATE119912T1
ATE119912T1 AT90915942T AT90915942T ATE119912T1 AT E119912 T1 ATE119912 T1 AT E119912T1 AT 90915942 T AT90915942 T AT 90915942T AT 90915942 T AT90915942 T AT 90915942T AT E119912 T1 ATE119912 T1 AT E119912T1
Authority
AT
Austria
Prior art keywords
group
pct
hydrogen atom
dione derivatives
atom
Prior art date
Application number
AT90915942T
Other languages
German (de)
English (en)
Inventor
Gerhard Hempel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of ATE119912T1 publication Critical patent/ATE119912T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT90915942T 1989-05-12 1990-05-07 Verfahren zur herstellung von 21-brom-4-pregnen- 3,20-dion-derivaten. ATE119912T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3915951A DE3915951C1 (US07223432-20070529-C00017.png) 1989-05-12 1989-05-12

Publications (1)

Publication Number Publication Date
ATE119912T1 true ATE119912T1 (de) 1995-04-15

Family

ID=6380760

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90915942T ATE119912T1 (de) 1989-05-12 1990-05-07 Verfahren zur herstellung von 21-brom-4-pregnen- 3,20-dion-derivaten.

Country Status (10)

Country Link
US (1) US5332847A (US07223432-20070529-C00017.png)
EP (1) EP0431151B1 (US07223432-20070529-C00017.png)
JP (1) JP2842690B2 (US07223432-20070529-C00017.png)
AT (1) ATE119912T1 (US07223432-20070529-C00017.png)
CA (1) CA2033065A1 (US07223432-20070529-C00017.png)
DD (1) DD297975A5 (US07223432-20070529-C00017.png)
DE (2) DE3915951C1 (US07223432-20070529-C00017.png)
DK (1) DK0431151T3 (US07223432-20070529-C00017.png)
ES (1) ES2071832T3 (US07223432-20070529-C00017.png)
WO (1) WO1990013558A1 (US07223432-20070529-C00017.png)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557158A (en) * 1962-01-22 1971-01-19 Upjohn Co 6alpha-fluoro-16-methyl - 4 - pregnene 3,20-diones and intermediates produced in the synthesis thereof
US3646012A (en) * 1967-10-05 1972-02-29 Wyeth John & Brother Ltd Enamine salt protection of steroidal alpha beta-unsaturated ketones
DE2118218A1 (en) * 1971-04-10 1972-10-26 Schering Ag, 1000 Berlin Und 4619 Bergkamen Tetrahalo steroids - prepd by simultaneous addn of fluorine and chlorine on the delta 9(11)-double bond
YU54476A (en) * 1975-03-31 1982-05-31 Taisho Pharmaceutical Co Ltd Process for obtaining 17-ester 21-halo-pregnane
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3400188A1 (de) * 1984-01-02 1985-07-11 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 6(alpha),16(alpha)-dimethylkortikoide
DE3640709A1 (de) * 1986-11-28 1988-06-09 Schering Ag Verfahren zur herstellung von 6(alpha),9(alpha)-difluor-11ss,17(alpha)-dihydroxy-16(alpha)-methyl-4-pregnen-3,20-dion und dessen derivate

Also Published As

Publication number Publication date
EP0431151A1 (de) 1991-06-12
JPH04500680A (ja) 1992-02-06
US5332847A (en) 1994-07-26
DE59008713D1 (de) 1995-04-20
EP0431151B1 (de) 1995-03-15
DD297975A5 (de) 1992-01-30
DE3915951C1 (US07223432-20070529-C00017.png) 1990-09-13
ES2071832T3 (es) 1995-07-01
WO1990013558A1 (de) 1990-11-15
CA2033065A1 (en) 1990-11-13
JP2842690B2 (ja) 1999-01-06
DK0431151T3 (da) 1995-07-24

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee