ATE116986T1 - Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate. - Google Patents
Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate.Info
- Publication number
- ATE116986T1 ATE116986T1 AT89304621T AT89304621T ATE116986T1 AT E116986 T1 ATE116986 T1 AT E116986T1 AT 89304621 T AT89304621 T AT 89304621T AT 89304621 T AT89304621 T AT 89304621T AT E116986 T1 ATE116986 T1 AT E116986T1
- Authority
- AT
- Austria
- Prior art keywords
- cephalosporins
- production
- pharmaceutical preparations
- optionally substituted
- ch2nr
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical group OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888811055A GB8811055D0 (en) | 1988-05-10 | 1988-05-10 | Antibiotic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE116986T1 true ATE116986T1 (de) | 1995-01-15 |
Family
ID=10636666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89304621T ATE116986T1 (de) | 1988-05-10 | 1989-05-08 | Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5055462A (de) |
| EP (1) | EP0341948B1 (de) |
| JP (1) | JPH01319486A (de) |
| AT (1) | ATE116986T1 (de) |
| DE (1) | DE68920474T2 (de) |
| GB (1) | GB8811055D0 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5232918A (en) * | 1987-07-23 | 1993-08-03 | Imperial Chemical Industries Plc | Cephalosporin derivatives |
| US5149803A (en) * | 1988-05-10 | 1992-09-22 | Imperial Chemical Industries Plc | Intermediates for cephalosporin compounds |
| EP0544166A3 (en) * | 1991-11-26 | 1993-11-03 | Hoffmann La Roche | Cephalosporinderivatives |
| DE19654920A1 (de) * | 1996-06-26 | 1998-01-08 | Gruenenthal Gmbh | Neue synthetische Catecholderivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DE19708846A1 (de) * | 1997-03-05 | 1998-09-17 | Gruenenthal Gmbh | Neue Benzoxazindionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| MX2011004636A (es) | 2008-10-31 | 2011-06-20 | Shionogi & Co | Cefarosporinas que tienen un grupo catecol. |
| EP2542076B1 (de) | 2010-03-04 | 2021-01-13 | Merck Sharp & Dohme Corp. | Hemmer der catechol-o-methyl-transferase und ihre verwendung bei der behandlung psychotischer störungen |
| JP5909441B2 (ja) | 2010-04-05 | 2016-04-26 | 塩野義製薬株式会社 | カテコール基を有するセフェム化合物 |
| JP5852562B2 (ja) | 2010-04-28 | 2016-02-03 | 塩野義製薬株式会社 | 新規なセフェム誘導体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4855420A (en) * | 1983-06-03 | 1989-08-08 | Ici Pharma | Cephalosporin derivatives |
| DE3750411T2 (de) * | 1986-04-14 | 1995-03-16 | Banyu Pharma Co Ltd | Cephalosporinderivate, Verfahren zu ihrer Herstellung und antibakterielle Präparate. |
| EP0265185A3 (de) * | 1986-10-21 | 1990-03-28 | Beecham Group Plc | Cephalosporine, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate |
| ZA877987B (en) * | 1986-11-12 | 1988-08-31 | Ici Pharma | Antibiotic compounds |
| US5189157A (en) * | 1987-06-16 | 1993-02-23 | Hoffmann La Roche Inc. | Antibacterial cephalosporin compounds |
| GB8816519D0 (en) * | 1987-07-23 | 1988-08-17 | Ici Plc | Antibiotic compounds |
-
1988
- 1988-05-10 GB GB888811055A patent/GB8811055D0/en active Pending
-
1989
- 1989-05-08 EP EP89304621A patent/EP0341948B1/de not_active Expired - Lifetime
- 1989-05-08 AT AT89304621T patent/ATE116986T1/de not_active IP Right Cessation
- 1989-05-08 DE DE68920474T patent/DE68920474T2/de not_active Expired - Fee Related
- 1989-05-10 US US07/349,662 patent/US5055462A/en not_active Expired - Fee Related
- 1989-05-10 JP JP1115243A patent/JPH01319486A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0341948A3 (de) | 1991-05-22 |
| GB8811055D0 (en) | 1988-06-15 |
| JPH01319486A (ja) | 1989-12-25 |
| DE68920474T2 (de) | 1995-06-01 |
| EP0341948A2 (de) | 1989-11-15 |
| EP0341948B1 (de) | 1995-01-11 |
| DE68920474D1 (de) | 1995-02-23 |
| US5055462A (en) | 1991-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |