ATE116322T1 - Kristallines cefadroxil und verfahren zu dessen herstellung. - Google Patents

Kristallines cefadroxil und verfahren zu dessen herstellung.

Info

Publication number
ATE116322T1
ATE116322T1 AT88100478T AT88100478T ATE116322T1 AT E116322 T1 ATE116322 T1 AT E116322T1 AT 88100478 T AT88100478 T AT 88100478T AT 88100478 T AT88100478 T AT 88100478T AT E116322 T1 ATE116322 T1 AT E116322T1
Authority
AT
Austria
Prior art keywords
cefadroxyl
novel
production
solvate
cefadroxil
Prior art date
Application number
AT88100478T
Other languages
English (en)
Inventor
Leonardo Marsili
Original Assignee
Rifar Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878709804A external-priority patent/GB8709804D0/en
Priority claimed from GB878718394A external-priority patent/GB8718394D0/en
Application filed by Rifar Srl filed Critical Rifar Srl
Application granted granted Critical
Publication of ATE116322T1 publication Critical patent/ATE116322T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT88100478T 1987-04-24 1988-01-14 Kristallines cefadroxil und verfahren zu dessen herstellung. ATE116322T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878709804A GB8709804D0 (en) 1987-04-24 1987-04-24 Crystalline cefadroxil
GB878718394A GB8718394D0 (en) 1987-08-04 1987-08-04 Crystalline cefadroxil hemihydrate
US07/089,168 US4904776A (en) 1987-04-24 1987-08-25 Method for producing crystalline cefadroxil hemihydrate

Publications (1)

Publication Number Publication Date
ATE116322T1 true ATE116322T1 (de) 1995-01-15

Family

ID=27263404

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88100478T ATE116322T1 (de) 1987-04-24 1988-01-14 Kristallines cefadroxil und verfahren zu dessen herstellung.

Country Status (13)

Country Link
US (1) US4904776A (de)
EP (1) EP0287751B1 (de)
JP (1) JP2620582B2 (de)
CN (1) CN1019804B (de)
AT (1) ATE116322T1 (de)
AU (1) AU595415B2 (de)
DE (1) DE3852560T2 (de)
DK (1) DK13888A (de)
ES (1) ES2068812T3 (de)
FI (1) FI87569C (de)
PH (1) PH26292A (de)
PT (1) PT86653B (de)
SU (1) SU1630613A3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714180D0 (en) * 1987-06-17 1987-07-22 Rifar Srl Anhydrous crystalline cefadroxil
WO1991000865A1 (en) * 1989-07-10 1991-01-24 Gema S.A. A novel stable form of cephradine, process for its production and intermediates used therein
IN190389B (de) 1999-07-14 2003-07-26 Ranbaxy Lab Ltd
AU5418300A (en) * 1999-07-14 2001-01-30 Ranbaxy Laboratories Limited Process for preparing crystalline cefadroxil hemihydrate from cefadroxil dimethylformamide solvate
CN1311830C (zh) * 2004-02-27 2007-04-25 石药集团中奇制药技术（石家庄）有限公司 头孢羟氨苄口腔崩解片及其制备方法
KR101420451B1 (ko) * 2006-05-19 2014-07-16 디에스엠 시노켐 파마슈티칼스 네덜란드 비.브이. 세파드록실의 결정화 방법
CN102134250B (zh) * 2011-01-19 2013-03-13 天津大学 一种头孢羟氨苄单水合物的结晶方法及结晶
CN104447795B (zh) * 2014-11-28 2016-08-17 珠海金鸿药业股份有限公司 一种头孢羟氨苄化合物及其药物组合物
CN105534937B (zh) * 2015-12-30 2019-12-03 石药集团欧意药业有限公司 一种头孢羟氨苄片剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4504697A (en) * 1982-04-28 1985-03-12 Littelfuse, Inc. Sealed electrical devices

Also Published As

Publication number Publication date
FI87569B (fi) 1992-10-15
EP0287751A3 (en) 1990-05-02
FI881038A0 (fi) 1988-03-07
CN88101895A (zh) 1988-11-30
ES2068812T3 (es) 1995-05-01
DK13888A (da) 1988-10-25
PT86653A (pt) 1988-02-01
JP2620582B2 (ja) 1997-06-18
US4904776A (en) 1990-02-27
EP0287751A2 (de) 1988-10-26
AU1028588A (en) 1988-10-27
DE3852560D1 (de) 1995-02-09
FI87569C (fi) 1993-01-25
AU595415B2 (en) 1990-03-29
FI881038A (fi) 1988-10-25
DK13888D0 (da) 1988-01-13
DE3852560T2 (de) 1995-05-04
JPS63267789A (ja) 1988-11-04
PT86653B (pt) 1992-07-31
PH26292A (en) 1992-04-10
EP0287751B1 (de) 1994-12-28
CN1019804B (zh) 1992-12-30
SU1630613A3 (ru) 1991-02-23

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Legal Events

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