ATE109352T1 - Heilung von wunden. - Google Patents
Heilung von wunden.Info
- Publication number
- ATE109352T1 ATE109352T1 AT89906917T AT89906917T ATE109352T1 AT E109352 T1 ATE109352 T1 AT E109352T1 AT 89906917 T AT89906917 T AT 89906917T AT 89906917 T AT89906917 T AT 89906917T AT E109352 T1 ATE109352 T1 AT E109352T1
- Authority
- AT
- Austria
- Prior art keywords
- healing
- wounds
- mammal
- growth factor
- purified
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 abstract 2
- 101000599951 Homo sapiens Insulin-like growth factor I Proteins 0.000 abstract 1
- 102100037852 Insulin-like growth factor I Human genes 0.000 abstract 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 abstract 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/196,975 US4983581A (en) | 1988-05-20 | 1988-05-20 | Wound healing composition of IGF-I and TGF-β |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE109352T1 true ATE109352T1 (de) | 1994-08-15 |
Family
ID=22727512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89906917T ATE109352T1 (de) | 1988-05-20 | 1989-05-22 | Heilung von wunden. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4983581A (de) |
| EP (1) | EP0419534B1 (de) |
| JP (1) | JPH0653674B2 (de) |
| AT (1) | ATE109352T1 (de) |
| DE (1) | DE68917300T2 (de) |
| WO (1) | WO1989011293A1 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256644A (en) * | 1988-05-20 | 1993-10-26 | Institute Of Molecular Biology, Inc. | Wound healing using IGF-II and TGF |
| US5145679A (en) * | 1989-10-05 | 1992-09-08 | Hinson Joan B | Topical emollient for prevention and treatment of circulatory induced lesions |
| ZA9010332B (en) * | 1989-12-22 | 1991-08-28 | Ciba Geigy | Method of reducing or preventing adverse effect of steroid therapy and compositions therefor |
| JP3377524B2 (ja) | 1990-05-30 | 2003-02-17 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 創傷治癒 |
| US6559119B1 (en) | 1990-11-27 | 2003-05-06 | Loyola University Of Chicago | Method of preparing a tissue sealant-treated biomedical material |
| US7189410B1 (en) | 1990-11-27 | 2007-03-13 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| US6117425A (en) * | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
| US6197325B1 (en) * | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| US6054122A (en) * | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| CA2097063C (en) * | 1990-11-27 | 2006-08-08 | Howard P. Greisler | Tissue sealant and growth factor containing compositions that promote accelerated wound healing |
| US6077823A (en) * | 1991-03-11 | 2000-06-20 | Creative Biomolecules, Inc. | Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury |
| US6211146B1 (en) * | 1991-03-11 | 2001-04-03 | Curis, Inc. | 60A protein-induced morphogenesis |
| CA2104678C (en) | 1991-03-11 | 2002-05-14 | Charles M. Cohen | Protein-induced morphogenesis |
| US5849686A (en) * | 1991-03-11 | 1998-12-15 | Creative Biomolecules, Inc. | Morphogen-induced liver regeneration |
| US5739107A (en) * | 1991-03-11 | 1998-04-14 | Creative Biomolecules, Inc. | Morphogen treatment of gastrointestinal ulcers |
| SE9101840L (sv) * | 1991-06-14 | 1992-12-15 | Kabi Pharmacia | Ny medicinsk anvaendning |
| WO1993024627A1 (en) * | 1992-06-03 | 1993-12-09 | Case Western Reserve University | Bandage for continuous application of biologicals |
| US5444047A (en) * | 1994-06-16 | 1995-08-22 | Dipasquale; Gene | Treatment of arthritic and post-surgical orthopedic conditions with Insulin-like Growth Factor-I |
| US5733884A (en) * | 1995-11-07 | 1998-03-31 | Nestec Ltd. | Enteral formulation designed for optimized wound healing |
| DE69723429T3 (de) | 1996-03-22 | 2007-09-20 | Curis, Inc., Cambridge | Verfahren zur verbesserten funktionellen Erholung der motorischen Koordination, der Sprache oder Sinneswahrnehmung nach Trauma oder Ischämie des ZNS |
| EP0920490A2 (de) * | 1996-07-25 | 1999-06-09 | Genzyme Corporation | Chondrozyten-medien formeln und kulturverfahren |
| US20030220269A1 (en) * | 1997-03-24 | 2003-11-27 | Fujisawa Pharmaceutical Co., Ltd. | Bile secretagogues |
| US6221997B1 (en) | 1997-04-28 | 2001-04-24 | Kimberly Ann Woodhouse | Biodegradable polyurethanes |
| US6762336B1 (en) | 1998-01-19 | 2004-07-13 | The American National Red Cross | Hemostatic sandwich bandage |
| EP2311485A1 (de) * | 1998-07-30 | 2011-04-20 | The Government of the United States of America, as represented by the Secretary of Health and Human Services | Thymosin beta 4 stimuliert Wundheilung |
| AU5862199A (en) | 1998-09-11 | 2000-04-03 | Michael Raschke | Biologically active implants |
| KR100385293B1 (ko) * | 2000-05-13 | 2003-05-23 | 주식회사 리젠 바이오텍 | βｉｇ-ｈ3의 일부 도메인을 이용한 세포 부착 및 창상치유 방법 |
| US6648911B1 (en) | 2000-11-20 | 2003-11-18 | Avantec Vascular Corporation | Method and device for the treatment of vulnerable tissue site |
| GB2369572A (en) * | 2000-11-29 | 2002-06-05 | Raft Trustees Ltd | Wound treatment composition comprising insulin |
| EP1545636B1 (de) | 2002-09-10 | 2015-01-07 | The American National Red Cross | Hämostatischer verband |
| JP5965573B2 (ja) * | 2006-08-04 | 2016-08-10 | エスティービー リミテッド | 創傷組織を治療するための固体包帯材 |
| WO2009020612A1 (en) * | 2007-08-06 | 2009-02-12 | Stb Lifesaving Technologies, Inc. | Methods and dressing for sealing internal injuries |
| US9669134B2 (en) | 2008-12-01 | 2017-06-06 | University College Cork, National University Of Ireland, Cork | IGF-I for myocardial repair |
| CN102781463A (zh) | 2009-10-07 | 2012-11-14 | 戈诺珍公司 | 用于皮肤再生的方法和组合物 |
| AU2015332556B2 (en) | 2014-10-14 | 2021-04-29 | Samuel Lynch | Compositions for treating wounds |
| US20210393746A1 (en) | 2018-09-26 | 2021-12-23 | National University Of Ireland, Galway | Treatment of myocardial infarction |
| CN114419192A (zh) | 2022-01-20 | 2022-04-29 | 腾讯科技（深圳）有限公司 | 引导线的显示方法、装置、设备、介质及程序产品 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US468590A (en) * | 1892-02-09 | Upper-folding machine | ||
| DE2558537C2 (de) * | 1975-12-24 | 1984-07-19 | Hellmut Dr. 8000 München Mittenzwei | Verfahren zum Isolieren von Substanzen mit insulinähnlicher Wirksamkeit aus Blut oder Blutbestandteilen von Kälbern oder Schweinen |
| US4350687A (en) * | 1980-02-10 | 1982-09-21 | Research Corporation | Platelet derived cell growth factor |
| US4479896A (en) * | 1981-12-11 | 1984-10-30 | Antoniades Harry N | Method for extraction localization and direct recovery of platelet derived growth factor |
| EP0105014B1 (de) * | 1982-09-24 | 1992-05-20 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Wiederherstellung von Gewebe bei Tieren |
| JPS6028999A (ja) * | 1983-06-30 | 1985-02-14 | Maruho Kk | 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法 |
| EP0154434B1 (de) * | 1984-02-17 | 1993-01-27 | Genentech, Inc. | Menschlicher Transformationswachstumsfaktor und Vorläufer oder Fragment hiervon, Zellen, DNA, Vektoren und Verfahren zu ihrer Herstellung, Zusammensetzungen und Produkte, die diese enthalten, sowie davon abgeleitete Antikörper und Diagnostizierverfahren |
| US4745179A (en) * | 1984-04-02 | 1988-05-17 | Fujisawa Pharmaceutical Co., Ltd. | 59 Valine insulin-like growth factor I and process for production thereof |
| US4738921A (en) * | 1984-09-27 | 1988-04-19 | Eli Lilly And Company | Derivative of the tryptophan operon for expression of fused gene products |
| US4702908A (en) * | 1985-11-01 | 1987-10-27 | Thorbecke G Jeanette | Composition containing platelet factor 4 and method for restoring suppressed immune responses |
| NZ222413A (en) * | 1986-11-05 | 1991-06-25 | Ethicon Inc | Compositions containing a polypeptide growth factor and a water-soluble cellulose polymer stabiliser |
| NZ226171A (en) * | 1987-09-18 | 1990-06-26 | Ethicon Inc | Gel formulation containing polypeptide growth factor |
-
1988
- 1988-05-20 US US07/196,975 patent/US4983581A/en not_active Expired - Lifetime
-
1989
- 1989-05-22 WO PCT/US1989/002229 patent/WO1989011293A1/en not_active Ceased
- 1989-05-22 AT AT89906917T patent/ATE109352T1/de not_active IP Right Cessation
- 1989-05-22 DE DE68917300T patent/DE68917300T2/de not_active Expired - Lifetime
- 1989-05-22 JP JP1506485A patent/JPH0653674B2/ja not_active Expired - Lifetime
- 1989-05-22 EP EP89906917A patent/EP0419534B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0419534A4 (en) | 1992-04-08 |
| DE68917300D1 (de) | 1994-09-08 |
| EP0419534B1 (de) | 1994-08-03 |
| WO1989011293A1 (en) | 1989-11-30 |
| EP0419534A1 (de) | 1991-04-03 |
| JPH03505870A (ja) | 1991-12-19 |
| US4983581A (en) | 1991-01-08 |
| DE68917300T2 (de) | 1995-02-23 |
| JPH0653674B2 (ja) | 1994-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |