ATE108798T1 - Carbapenemderivate. - Google Patents

Carbapenemderivate.

Info

Publication number
ATE108798T1
ATE108798T1 AT89120631T AT89120631T ATE108798T1 AT E108798 T1 ATE108798 T1 AT E108798T1 AT 89120631 T AT89120631 T AT 89120631T AT 89120631 T AT89120631 T AT 89120631T AT E108798 T1 ATE108798 T1 AT E108798T1
Authority
AT
Austria
Prior art keywords
group
alkyl group
chem
nitrogen
carbon atoms
Prior art date
Application number
AT89120631T
Other languages
English (en)
Inventor
Makoto Daiichi Pharma Takemura
Toshiyuki Daiichi Pharma Nishi
Hiroshi Daiichi Pharmac Susaki
Youhei Daiichi Pharmace Ishida
Hiroko Daiichi Pharmaceut Koda
Takeshi Daiichi Pharmac Hayano
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE108798T1 publication Critical patent/ATE108798T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
AT89120631T 1988-11-08 1989-11-07 Carbapenemderivate. ATE108798T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28179888 1988-11-08

Publications (1)

Publication Number Publication Date
ATE108798T1 true ATE108798T1 (de) 1994-08-15

Family

ID=17644130

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89120631T ATE108798T1 (de) 1988-11-08 1989-11-07 Carbapenemderivate.

Country Status (7)

Country Link
US (1) US5583218A (de)
EP (1) EP0368259B1 (de)
AT (1) ATE108798T1 (de)
CA (1) CA2002551C (de)
DE (1) DE68916908T2 (de)
ES (1) ES2059679T3 (de)
HU (1) HU211267A9 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8923844D0 (en) * 1989-10-23 1989-12-13 Fujisawa Pharmaceutical Co Carbapenem compounds
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
CA2184101C (en) * 1994-02-25 2005-11-22 Susumu Nakagawa Carbapenem derivatives
JP4377231B2 (ja) * 2001-11-05 2009-12-02 大日本住友製薬株式会社 新規なカルバペネム化合物
CA2519794A1 (en) 2003-04-08 2004-10-21 Sumitomo Pharmaceuticals Co., Ltd. Novel carbapenem compounds
US20070265242A1 (en) * 2004-09-03 2007-11-15 Makoto Sunagawa Novel Carbapenem Compound
US20090029964A1 (en) * 2005-03-25 2009-01-29 Makoto Sunagawa Novel carbapenem compound
EP2167071B1 (de) 2007-06-13 2020-03-18 Wayne State University Board Of Governors Baclofen-lösung zur niedrigvolumigen therapeutischen abgabe
US20100210604A1 (en) * 2007-06-13 2010-08-19 Meythaler Jay M Zwitterion solution for low-volume therapeutic delivery
US10519161B2 (en) 2012-10-29 2019-12-31 Southern Methodist University Methods of generating beta-lactamase resistant carbapenem compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids
ES514240A0 (es) * 1981-08-03 1984-04-16 Merck & Co Inc Un procedimiento para la prepracion de nuevos derivados de acidos 2-carbamimidoil-1-,carbadestiapen-2-en-3-carboxilados.
IE851586L (en) * 1984-07-02 1986-01-02 Interchem Internat S A I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent
CA1285940C (en) * 1984-07-02 1991-07-09 Merck & Co., Inc. Carbapenems having a 2-quaternary heteroarylalkylthio substituent
PH24782A (en) * 1985-10-24 1990-10-30 Sankyo Co Composition containing a penem or carbapenem antibiotic and the use of the same
JPS6425779A (en) * 1987-04-11 1989-01-27 Lederle Japan Ltd (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative

Also Published As

Publication number Publication date
EP0368259A1 (de) 1990-05-16
DE68916908T2 (de) 1994-12-01
HU211267A9 (en) 1995-11-28
US5583218A (en) 1996-12-10
CA2002551A1 (en) 1990-05-08
EP0368259B1 (de) 1994-07-20
DE68916908D1 (de) 1994-08-25
CA2002551C (en) 1999-04-06
ES2059679T3 (es) 1994-11-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee