ATE105302T1 - Fluoramid-derivate mit hemmender aktivitaet gegen menschliche leukozytenelastase. - Google Patents
Fluoramid-derivate mit hemmender aktivitaet gegen menschliche leukozytenelastase.Info
- Publication number
- ATE105302T1 ATE105302T1 AT9090304903T AT90304903T ATE105302T1 AT E105302 T1 ATE105302 T1 AT E105302T1 AT 9090304903 T AT9090304903 T AT 9090304903T AT 90304903 T AT90304903 T AT 90304903T AT E105302 T1 ATE105302 T1 AT E105302T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- human leukocyte
- elastasis
- fluoramide
- activity against
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898910547A GB8910547D0 (en) | 1989-05-08 | 1989-05-08 | Substituted ketones |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE105302T1 true ATE105302T1 (de) | 1994-05-15 |
Family
ID=10656399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT9090304903T ATE105302T1 (de) | 1989-05-08 | 1990-05-04 | Fluoramid-derivate mit hemmender aktivitaet gegen menschliche leukozytenelastase. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5270301A (de) |
EP (1) | EP0397427B1 (de) |
JP (1) | JP2872748B2 (de) |
AT (1) | ATE105302T1 (de) |
AU (1) | AU622316B2 (de) |
CA (1) | CA2016209A1 (de) |
DE (1) | DE69008615T2 (de) |
DK (1) | DK0397427T3 (de) |
ES (1) | ES2053107T3 (de) |
GB (1) | GB8910547D0 (de) |
IE (1) | IE63573B1 (de) |
NZ (1) | NZ233514A (de) |
ZA (1) | ZA903343B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8809316D0 (en) * | 1987-05-11 | 1988-05-25 | Ici America Inc | Heterocyclic ketones |
GB8910550D0 (en) * | 1989-05-08 | 1989-06-21 | Ici America Inc | Substituted amides |
CA2021660A1 (en) * | 1989-07-26 | 1991-01-27 | Philippe Bey | Peptidase inhibitors |
US5441960A (en) * | 1992-04-16 | 1995-08-15 | Zeneca Limited | 1-pyrimidinylacetamide human leukocyte elastate inhibitors |
US5486529A (en) * | 1992-04-16 | 1996-01-23 | Zeneca Limited | Certain pyridyl ketones for treating diseases involving leukocyte elastase |
GB9211783D0 (en) * | 1992-06-04 | 1992-07-15 | Ici Plc | Amide derivatives |
IL108031A0 (en) * | 1992-12-22 | 1994-04-12 | Procter & Gamble | Difluoro pentapeptide derivatives and pharmaceutical compositions containing them |
US5885967A (en) * | 1994-03-04 | 1999-03-23 | Eli Lilly And Company | Antithrombotic agents |
WO2004065383A2 (en) * | 2003-01-16 | 2004-08-05 | Teva Pharmaceutical Industries Ltd. | Novel synthesis of irbesartan |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4256761A (en) * | 1979-07-13 | 1981-03-17 | Usv Pharmaceutical Corporation | Antihypertensive amides |
GB8600263D0 (en) * | 1985-01-22 | 1986-02-12 | Ici America Inc | Peptide derivatives |
EP0204571B1 (de) * | 1985-06-07 | 1992-01-22 | Ici Americas Inc. | Selektionierte Difluorverbindungen |
GB8613704D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro keto compounds |
DE3782191T2 (de) * | 1986-06-05 | 1993-02-25 | Ici America Inc | Difluorketoverbindungen. |
EP0276101A3 (de) * | 1987-01-19 | 1989-11-23 | Ici Americas Inc. | Substituierte Peptid-Derivate |
GB8809316D0 (en) * | 1987-05-11 | 1988-05-25 | Ici America Inc | Heterocyclic ketones |
EP0369391A3 (de) * | 1988-11-15 | 1991-09-25 | Boehringer Ingelheim Pharmaceuticals Inc. | N-substituierte Amide |
GB8910550D0 (en) * | 1989-05-08 | 1989-06-21 | Ici America Inc | Substituted amides |
-
1989
- 1989-05-08 GB GB898910547A patent/GB8910547D0/en active Pending
-
1990
- 1990-05-01 NZ NZ233514A patent/NZ233514A/en unknown
- 1990-05-01 AU AU54565/90A patent/AU622316B2/en not_active Ceased
- 1990-05-02 ZA ZA903343A patent/ZA903343B/xx unknown
- 1990-05-04 DK DK90304903.9T patent/DK0397427T3/da active
- 1990-05-04 AT AT9090304903T patent/ATE105302T1/de not_active IP Right Cessation
- 1990-05-04 EP EP90304903A patent/EP0397427B1/de not_active Expired - Lifetime
- 1990-05-04 DE DE69008615T patent/DE69008615T2/de not_active Expired - Fee Related
- 1990-05-04 ES ES90304903T patent/ES2053107T3/es not_active Expired - Lifetime
- 1990-05-07 CA CA002016209A patent/CA2016209A1/en not_active Abandoned
- 1990-05-07 IE IE165390A patent/IE63573B1/en not_active IP Right Cessation
- 1990-05-07 US US07/519,618 patent/US5270301A/en not_active Expired - Fee Related
- 1990-05-08 JP JP2118526A patent/JP2872748B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IE901653L (en) | 1990-11-08 |
ES2053107T3 (es) | 1994-07-16 |
DE69008615D1 (de) | 1994-06-09 |
AU5456590A (en) | 1990-11-15 |
JPH0356496A (ja) | 1991-03-12 |
DK0397427T3 (da) | 1994-06-06 |
EP0397427B1 (de) | 1994-05-04 |
GB8910547D0 (en) | 1989-06-21 |
AU622316B2 (en) | 1992-04-02 |
JP2872748B2 (ja) | 1999-03-24 |
CA2016209A1 (en) | 1990-11-08 |
IE63573B1 (en) | 1995-05-17 |
DE69008615T2 (de) | 1994-08-18 |
ZA903343B (en) | 1991-01-30 |
US5270301A (en) | 1993-12-14 |
EP0397427A1 (de) | 1990-11-14 |
NZ233514A (en) | 1993-01-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69231513D1 (de) | Pyrimidinyl-Essigsäureamide als Elastase Inhibitoren | |
MX9302219A (es) | Cetonas heterociclicas. | |
TW262475B (en) | Heterocyclic amides, intermediates and process for their preparation and pharmaceutical compositions containing them | |
EP0636143A1 (de) | Peptide mit eine alphaaminoboronaire gruppe and ihre verwendung als elastasehemmer. | |
FI944802A (fi) | HLE-proteiinien aktiivisuutta inhiboivat laktaamidipeptidit | |
FI945696A (fi) | Laktaamidipeptidejä, joilla on HLE:a inhiboiva aktiivisuus | |
ATE105302T1 (de) | Fluoramid-derivate mit hemmender aktivitaet gegen menschliche leukozytenelastase. | |
ATE171191T1 (de) | Fluorenthaltende dipeptide als inhibitoren gegen elastase menschliches leukocyten | |
DK0399688T3 (da) | Trifluorketopeptidderivater, som er nyttige som human leukocyt-elastaseinhibitorer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |