ATE10277T1 - Verfahren zur herstellung von heterozyklylalkylguanidinen, zwischenprodukte und deren herstellung. - Google Patents

Verfahren zur herstellung von heterozyklylalkylguanidinen, zwischenprodukte und deren herstellung.

Info

Publication number
ATE10277T1
ATE10277T1 AT81302336T AT81302336T ATE10277T1 AT E10277 T1 ATE10277 T1 AT E10277T1 AT 81302336 T AT81302336 T AT 81302336T AT 81302336 T AT81302336 T AT 81302336T AT E10277 T1 ATE10277 T1 AT E10277T1
Authority
AT
Austria
Prior art keywords
formula
hydrogen
preparation
chem
group
Prior art date
Application number
AT81302336T
Other languages
English (en)
Inventor
Derek William Hills
George Raymond White
Original Assignee
Smith Kline & French Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline & French Laboratories Limited filed Critical Smith Kline & French Laboratories Limited
Application granted granted Critical
Publication of ATE10277T1 publication Critical patent/ATE10277T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT81302336T 1980-05-31 1981-05-27 Verfahren zur herstellung von heterozyklylalkylguanidinen, zwischenprodukte und deren herstellung. ATE10277T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8017881 1980-05-31
AU71026/81A AU542270B2 (en) 1980-05-31 1981-05-26 Imidazolylalkylguanidine derivatives

Publications (1)

Publication Number Publication Date
ATE10277T1 true ATE10277T1 (de) 1984-11-15

Family

ID=36782531

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81302336T ATE10277T1 (de) 1980-05-31 1981-05-27 Verfahren zur herstellung von heterozyklylalkylguanidinen, zwischenprodukte und deren herstellung.

Country Status (9)

Country Link
EP (1) EP0041359B1 (de)
JP (1) JPS5724387A (de)
AT (1) ATE10277T1 (de)
AU (1) AU542270B2 (de)
DE (1) DE3167163D1 (de)
DK (1) DK221081A (de)
GR (1) GR75661B (de)
IE (1) IE52019B1 (de)
ZA (1) ZA813659B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58157768A (ja) * 1982-03-16 1983-09-19 Takeda Chem Ind Ltd ４−クロロ−２−フエニルイミダゾ−ル−５−酢酸誘導体
EP0199845B1 (de) * 1985-04-02 1990-08-01 HEUMANN PHARMA GMBH & CO Imidazolylalkylguanidinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3621104A1 (de) * 1986-06-24 1988-01-07 Heumann Pharma Gmbh & Co 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3631334A1 (de) * 1986-09-15 1988-03-17 Heumann Pharma Gmbh & Co Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
NL9100365A (nl) * 1991-02-27 1992-09-16 Seed Capital Investments Imidazoolderivaten met agonistische of antagonistische activiteit op de histamine h3-receptor.
WO1992015567A1 (en) * 1991-02-27 1992-09-17 Seed Capital Investment (Sci) B.V. Imidazole-derivatives having agonistic or antagonistic activity on the histamine h3-receptor
USRE37303E1 (en) * 1992-01-10 2001-07-31 Institut National Del La Sante Et De La Recherche Medicale Imidazole compounds and their therapeutic applications
FR2686084B1 (fr) * 1992-01-10 1995-12-22 Bioprojet Soc Civ Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763179A (en) * 1972-05-05 1973-10-02 Upjohn Co 2-imidazol-1-yl benzophenones
FR2254311A1 (en) * 1973-12-13 1975-07-11 Smith Kline French Lab 4-Alkyl-5-(2-aminoethyl)imidazole compsns - for diagnosing secretory activity of the stomach, prepd eg from 4-methylhistamine or hex-3-yne-1-ol

Also Published As

Publication number Publication date
JPS5724387A (en) 1982-02-08
DK221081A (da) 1981-12-01
AU542270B2 (en) 1985-02-14
AU7102681A (en) 1981-12-10
DE3167163D1 (en) 1984-12-20
ZA813659B (en) 1982-08-25
IE52019B1 (en) 1987-05-27
EP0041359B1 (de) 1984-11-14
GR75661B (de) 1984-08-02
IE811202L (en) 1981-11-30
EP0041359A1 (de) 1981-12-09

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