ATE102612T1 - 2-IMINO-3 HETEROCYCLYLAMINO-BENZOTHIAZOLINE, THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM. - Google Patents

2-IMINO-3 HETEROCYCLYLAMINO-BENZOTHIAZOLINE, THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM.

Info

Publication number
ATE102612T1
ATE102612T1 AT90401976T AT90401976T ATE102612T1 AT E102612 T1 ATE102612 T1 AT E102612T1 AT 90401976 T AT90401976 T AT 90401976T AT 90401976 T AT90401976 T AT 90401976T AT E102612 T1 ATE102612 T1 AT E102612T1
Authority
AT
Austria
Prior art keywords
preparation
benzothiazoline
heterocyclylamino
imino
pharmaceuticals containing
Prior art date
Application number
AT90401976T
Other languages
German (de)
Inventor
Patrick Jimonet
Blevec Joseph Le
Conception Nemecek
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8909483A external-priority patent/FR2649704B1/en
Priority claimed from FR9005889A external-priority patent/FR2661910B1/en
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Application granted granted Critical
Publication of ATE102612T1 publication Critical patent/ATE102612T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of formula: <IMAGE> in which R1 denotes a substituted 1-piperazinyl, substituted 1,2,3,6-tetrahydro-1-pyridyl or substituted piperidino radical, R2 denotes a polyfluoroalkoxy radical and n is equal to 2 or 3, salts of these compounds with an acid, processes for their preparation and medications containing them.
AT90401976T 1989-07-13 1990-07-09 2-IMINO-3 HETEROCYCLYLAMINO-BENZOTHIAZOLINE, THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM. ATE102612T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8909483A FR2649704B1 (en) 1989-07-13 1989-07-13 IMINO-2 ETHYL-3 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICINAL PRODUCTS CONTAINING THEM
FR9005889A FR2661910B1 (en) 1990-05-11 1990-05-11 IMINO-2 HETEROCYCLYLALKYL-3 BENZOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
EP90401976A EP0409692B1 (en) 1989-07-13 1990-07-09 2 Imino-3 heterocyclylamino benzothiazoline, their preparation and medicine containing them

Publications (1)

Publication Number Publication Date
ATE102612T1 true ATE102612T1 (en) 1994-03-15

Family

ID=26227474

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90401976T ATE102612T1 (en) 1989-07-13 1990-07-09 2-IMINO-3 HETEROCYCLYLAMINO-BENZOTHIAZOLINE, THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM.

Country Status (20)

Country Link
EP (1) EP0409692B1 (en)
JP (1) JPH0386871A (en)
AT (1) ATE102612T1 (en)
AU (1) AU624972B2 (en)
CA (1) CA2021031A1 (en)
CZ (1) CZ281164B6 (en)
DE (1) DE69007196T2 (en)
DK (1) DK0409692T3 (en)
ES (1) ES2062445T3 (en)
FI (1) FI93109C (en)
HU (1) HU210827B (en)
IE (1) IE63318B1 (en)
IL (1) IL95053A (en)
NO (1) NO175590C (en)
NZ (1) NZ234487A (en)
PL (2) PL164326B1 (en)
PT (1) PT94701B (en)
RU (1) RU1836368C (en)
SK (1) SK278908B6 (en)
YU (1) YU47723B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674853B1 (en) * 1991-04-03 1995-01-20 Synthelabo PIPERIDINYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2678619B1 (en) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa DERIVATIVES OF 1,2,4-THIADIAZOLO [3,4-B] BENZOTHIAZOLE, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
AU3957093A (en) * 1992-04-15 1993-11-18 Rhone-Poulenc Rorer S.A. 3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxyl ic acid derivatives, preparation thereof and drugs containing same
FR2696457B1 (en) * 1992-10-02 1994-11-25 Rhone Poulenc Rorer Sa Derivatives of 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, their preparation and the medicaments containing them.
US5889010A (en) * 1995-05-18 1999-03-30 Pfizer Inc. Benzimidazole derivatives having dopaminergic activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (en) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Process for the preparation of 2-iminobenzothiazoles
FR2492258A1 (en) * 1980-10-17 1982-04-23 Pharmindustrie NEW AMINO-2 TRIFLUOROMETHOXY-6 BENZOTHIAZOLE-BASED MEDICINAL PRODUCT
US4980356A (en) * 1988-12-15 1990-12-25 Rhone-Poulenc Sante 2-imino-6-polyfluoroalkoxybenzothiazole derivatives, and pharamaceutical compositions containing them and their treatment of medical conditions associated with the effects of glutamate
FR2649701B2 (en) * 1988-12-15 1991-11-22 Rhone Poulenc Sante IMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM

Also Published As

Publication number Publication date
SK342590A3 (en) 1998-04-08
AU624972B2 (en) 1992-06-25
NO903113L (en) 1991-01-14
CZ281164B6 (en) 1996-07-17
PT94701A (en) 1991-03-20
PL164152B1 (en) 1994-06-30
NO903113D0 (en) 1990-07-12
RU1836368C (en) 1993-08-23
PT94701B (en) 1997-03-31
FI93109B (en) 1994-11-15
EP0409692A3 (en) 1991-03-27
IL95053A (en) 1994-05-30
CA2021031A1 (en) 1991-01-14
EP0409692A2 (en) 1991-01-23
JPH0386871A (en) 1991-04-11
IL95053A0 (en) 1991-06-10
PL164326B1 (en) 1994-07-29
HU904189D0 (en) 1990-12-28
IE63318B1 (en) 1995-04-05
DE69007196T2 (en) 1994-06-30
DE69007196D1 (en) 1994-04-14
DK0409692T3 (en) 1994-04-05
FI93109C (en) 1995-02-27
FI903531A0 (en) 1990-07-12
IE902551A1 (en) 1991-02-27
AU5884790A (en) 1991-01-17
NO175590C (en) 1994-11-02
YU133990A (en) 1992-07-20
CZ342590A3 (en) 1996-01-17
ES2062445T3 (en) 1994-12-16
EP0409692B1 (en) 1994-03-09
NO175590B (en) 1994-07-25
NZ234487A (en) 1992-04-28
YU47723B (en) 1996-01-08
SK278908B6 (en) 1998-04-08
HUT58732A (en) 1992-03-30
HU210827B (en) 1995-08-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee