ATE101350T1 - Vorrichtung zur transdermalen applikation von wirksamen substanzen. - Google Patents

Vorrichtung zur transdermalen applikation von wirksamen substanzen.

Info

Publication number
ATE101350T1
ATE101350T1 AT87306033T AT87306033T ATE101350T1 AT E101350 T1 ATE101350 T1 AT E101350T1 AT 87306033 T AT87306033 T AT 87306033T AT 87306033 T AT87306033 T AT 87306033T AT E101350 T1 ATE101350 T1 AT E101350T1
Authority
AT
Austria
Prior art keywords
active substances
electrode
transdermal application
skin
contact
Prior art date
Application number
AT87306033T
Other languages
English (en)
Inventor
Yvonne Brigid Bannon
John Corish
Owen Ignatius Corrigan
Joseph G Masterson
Original Assignee
Elan Transdermal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Transdermal Ltd filed Critical Elan Transdermal Ltd
Application granted granted Critical
Publication of ATE101350T1 publication Critical patent/ATE101350T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Finger-Pressure Massage (AREA)
AT87306033T 1986-07-10 1987-07-08 Vorrichtung zur transdermalen applikation von wirksamen substanzen. ATE101350T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE185486A IE60941B1 (en) 1986-07-10 1986-07-10 Transdermal drug delivery device
EP87306033A EP0252732B1 (de) 1986-07-10 1987-07-08 Vorrichtung zur transdermalen Applikation von wirksamen Substanzen

Publications (1)

Publication Number Publication Date
ATE101350T1 true ATE101350T1 (de) 1994-02-15

Family

ID=11031295

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87306033T ATE101350T1 (de) 1986-07-10 1987-07-08 Vorrichtung zur transdermalen applikation von wirksamen substanzen.

Country Status (13)

Country Link
US (1) US5135480A (de)
EP (1) EP0252732B1 (de)
JP (1) JPH0626591B2 (de)
KR (1) KR950008026B1 (de)
AT (1) ATE101350T1 (de)
AU (1) AU591997B2 (de)
CA (1) CA1319578C (de)
DE (1) DE3789035T2 (de)
ES (1) ES2051270T3 (de)
IE (1) IE60941B1 (de)
NZ (1) NZ221013A (de)
PH (1) PH26087A (de)
ZA (1) ZA875002B (de)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US5032109A (en) * 1987-02-10 1991-07-16 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US4878892A (en) * 1987-02-10 1989-11-07 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
EP0313638A4 (de) * 1987-05-15 1989-06-14 Martin H Newman Arzneimittelverabreichungssystem durch inophorese.
US5362307A (en) * 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
JP2907342B2 (ja) * 1988-01-29 1999-06-21 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア イオン滲透非侵襲的サンプリングまたは送出装置
DE69029399T2 (de) * 1989-10-23 1997-04-17 Theratech Inc Vorrichtung für Iontophorese unter Verwendung einer Durchfluss-kontrollierenden Membran
US5334138A (en) * 1990-03-15 1994-08-02 North Carolina State University Method and composition for increased skin concentration of active agents by iontophoresis
ES2082973T3 (es) * 1990-03-30 1996-04-01 Alza Corp Dispositivo para administracion iontoforetica de farmacos.
JP3740549B2 (ja) * 1990-03-30 2006-02-01 アルザ・コーポレーション イオン侵透療法による薬剤投与の装置と方法
US5383848A (en) * 1990-04-12 1995-01-24 Gensia, Inc. Iontophoretic administration of drugs
US5362308A (en) * 1990-09-25 1994-11-08 Rutgers, The State University Of New Jersey Disposable dosage unit for iontophoresis-facilitated transdermal delivery, related devices and processes
EP0575508B1 (de) * 1991-03-11 1994-10-05 Alza Corporation Iontophoretisches verabreichungssystem und verfahren zu seiner herstellung
US5221254A (en) * 1991-04-02 1993-06-22 Alza Corporation Method for reducing sensation in iontophoretic drug delivery
US5356632A (en) * 1991-09-12 1994-10-18 S.I. Scientific Innovations Ltd. Transdermal drug delivery device
SE9102778D0 (sv) * 1991-09-25 1991-09-25 Siemens Elema Ab Implanterbar medicinsk anordning
EP0608320B1 (de) * 1991-10-16 1998-01-28 Richardson-Vicks, Inc. Verbesserte hautpenetrationssysteme fuer erhoehte topische freisetzung von arzneimitteln
US5405614A (en) * 1992-04-08 1995-04-11 International Medical Associates, Inc. Electronic transdermal drug delivery system
ATE162728T1 (de) 1992-12-31 1998-02-15 Alza Corp Elektrophorese-system mit biegsamen mitteln
ATE322271T1 (de) * 1993-01-19 2006-04-15 Endorech Inc Therapeutische verwendungen von dehydroepiandrosteron zur behandlung von verminderter libido und osteoporose
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
US5427585A (en) * 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
FR2709670B1 (fr) * 1993-09-10 1995-10-20 Asulab Sa Dispositif en trois modules pour l'administration transdermique de médicaments par électrophorèse ou iontophorèse.
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
KR0134151B1 (ko) * 1994-05-23 1998-04-14 이형도 인슐린 패치
US5771890A (en) 1994-06-24 1998-06-30 Cygnus, Inc. Device and method for sampling of substances using alternating polarity
UA10911C2 (uk) * 1994-08-10 1996-12-25 Мале Впроваджувальне Підприємство "Іhтерфалл" Біосумісhий гідрогель
US5540654A (en) * 1994-09-02 1996-07-30 North Carolina State University Iontophoretic electrode
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
CA2217014A1 (en) * 1995-04-07 1996-10-10 Novartis Ag Iontophoretic transdermal system for the administration of at least two substances
US6086921A (en) 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US6355025B1 (en) * 1995-06-07 2002-03-12 Alza Corporation Adjustable electrotransport drug delivery using a fixed output controller
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
EP0747092B1 (de) * 1995-06-09 2003-12-03 Hisamitsu Pharmaceutical Co., Inc. Matrix für Iontophorese
US5989409A (en) * 1995-09-11 1999-11-23 Cygnus, Inc. Method for glucose sensing
WO1997014473A1 (en) * 1995-10-18 1997-04-24 Novartis Ag Thermopile powered transdermal drug delivery device
SI9620126A (sl) * 1995-12-15 1999-10-31 Cryopreservation Technologies Cc (Za/Za) Spojina za kriogensko ohranjanje organov in zdravljenje virusnih ter bakterijskih infekcij
US6175763B1 (en) 1996-03-29 2001-01-16 Alza Corporation Electrotransport drug delivery device having tactile signaling means
US5954685A (en) * 1996-05-24 1999-09-21 Cygnus, Inc. Electrochemical sensor with dual purpose electrode
AU3404097A (en) * 1996-06-19 1998-01-07 Becton Dickinson & Company Iontophoretic delivery of cell adhesion inhibitors
CA2208332A1 (en) * 1996-06-20 1997-12-20 Hisamitsu Pharmaceuticals Co., Inc. Drug administration composition for iontophoresis
US5908400A (en) * 1996-06-20 1999-06-01 Hisamitsu Pharmaceutical Co., Inc. Device structure for iontophoresis
US6139718A (en) * 1997-03-25 2000-10-31 Cygnus, Inc. Electrode with improved signal to noise ratio
ZA984649B (en) * 1997-06-13 1999-12-17 Cryopreservation Tech Cc "Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes".
US5971722A (en) * 1997-09-05 1999-10-26 Baxter International Inc Electrochemical syringe pump having a sealed storage reservoir for a charge transfer medium
BR9911115A (pt) 1998-06-11 2001-12-04 Endorech Inc Composições farmacêuticas e usos para oandrost-5-eno-3 beta, 17 beta-diol
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6147102A (en) * 1999-10-26 2000-11-14 Curatek Pharmaceuticals Holding, Inc. Clonidine preparations
DE10025890A1 (de) * 2000-05-25 2001-11-29 Euro Celtique Sa Dosierung von transdermalen Arzneimittelsystemen
US7186419B2 (en) * 2000-08-25 2007-03-06 Contura Sa Polyacrylamide hydrogel for arthritis
MY130475A (en) * 2000-08-25 2007-06-29 Contura As Polyacrylamide hydrogel and its use as an endoprosthesis
US6453195B1 (en) 2001-03-19 2002-09-17 Medtronic, Inc. Closed loop drug delivery system and remote management thereof
US7272433B2 (en) * 2001-04-30 2007-09-18 Medtronic, Inc. Transcutaneous monitor and method of use, using therapeutic output from an implanted medical device
DE10137162A1 (de) * 2001-07-30 2003-02-20 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol
SE0103293D0 (sv) * 2001-10-03 2001-10-03 Painmatcher Ab Finger electrode and support structure
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US7099713B2 (en) 2002-06-28 2006-08-29 Battelle Memorial Institute Skin conduction and transport systems
US7458982B2 (en) * 2002-10-04 2008-12-02 Photokinetix, Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
US7147955B2 (en) * 2003-01-31 2006-12-12 Societe Bic Fuel cartridge for fuel cells
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20090254018A1 (en) * 2005-08-24 2009-10-08 Mizuo Nakayama Electrode assembly for freezing-type iontophoresis device
BRPI0616165A2 (pt) 2005-09-15 2011-06-07 Tti Ellebeau Inc dispositivo de iontoforese do tipo de haste
US8812112B2 (en) 2005-11-10 2014-08-19 ElectroCore, LLC Electrical treatment of bronchial constriction
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
US8041428B2 (en) 2006-02-10 2011-10-18 Electrocore Llc Electrical stimulation treatment of hypotension
US7747324B2 (en) 2005-11-10 2010-06-29 Electrocore Llc Electrical stimulation treatment of bronchial constriction
TW200800223A (en) * 2005-12-21 2008-01-01 Shire Pharmaceuticals Inc Transdermal delivery of meptazinol
US20070185431A1 (en) * 2006-02-03 2007-08-09 Kern Dale G Galvanic Current Skin Treatment
JP2009525805A (ja) 2006-02-10 2009-07-16 エレクトロコア、インコーポレイテッド 電気的変調を用いたアナフィラキシーの治療方法および治療装置
WO2007094828A2 (en) * 2006-02-10 2007-08-23 Electrocore, Inc. Electrical stimulation treatment of hypotension
KR101214764B1 (ko) * 2006-11-14 2012-12-21 가고시마 유니버시티 약물주입장치
KR20090106492A (ko) * 2006-12-01 2009-10-09 티티아이 엘뷰 가부시키가이샤 경피성 전달 장치와 같은 장치에 전력을 제공하거나 제어하기 위한 시스템, 장치, 및 방법
US20080188778A1 (en) * 2007-02-02 2008-08-07 Yu-Yu Chen Array percutaneous therapeutic apparatus
FR2913600B1 (fr) * 2007-03-13 2011-02-25 Dbv Tech Dispositif pour l'application cutanee de substances.
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
EP2164418B1 (de) * 2007-06-27 2014-01-08 The General Hospital Corporation Vorrichtung zur optischen unterdrückung einer photodynamischen therapie
CA2988753A1 (en) 2007-08-06 2009-02-12 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
EP4166107A1 (de) 2008-05-09 2023-04-19 Nuvaira, Inc. Systeme, anordnungen und verfahren zur behandlung eines bronchialbaums
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
JP5767103B2 (ja) 2008-05-21 2015-08-19 フエリング・インターナシヨナル・センター・エス・アー 夜間頻尿によって妨げられない睡眠の初期期間を増加させるための口腔内崩壊デスモプレシン
US20100317635A1 (en) 2009-06-16 2010-12-16 Endorecherche, Inc. Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
ES2929471T3 (es) 2009-06-18 2022-11-29 Acerus Pharmaceuticals Usa Llc Administración segura de desmopresina
CN104042322B (zh) 2009-10-27 2017-06-06 赫莱拉公司 具有可冷却的能量发射组件的递送装置
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
WO2011060200A1 (en) 2009-11-11 2011-05-19 Innovative Pulmonary Solutions, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US11607407B2 (en) 2010-04-13 2023-03-21 Relmada Therapeutics, Inc. Dermal pharmaceutical compositions of 1-methyl-2′,6′-pipecoloxylidide and method of use
KR20140089402A (ko) 2010-06-16 2014-07-14 앙도르쉐르슈 인코포레이티드 에스트로겐-관련 질병의 치료 또는 예방 방법
ES1073640Y (es) * 2010-06-22 2011-04-11 De La Iglesia Marta Perez Pulsera de administracion transdermica de nicotina
US9433459B2 (en) 2010-07-13 2016-09-06 Zoll Medical Corporation Deposit ablation within and external to circulatory systems
WO2014055359A1 (en) * 2012-10-01 2014-04-10 DUPELLE, Mary, Ann Deposit ablation within and external to circulatory systems
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US9744177B2 (en) 2014-03-10 2017-08-29 Endorecherche, Inc. Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
KR20150144209A (ko) * 2014-06-16 2015-12-24 훼링 비.브이. 안정화된 데스모프레신 또는 이의 약학적으로 허용가능한 염을 함유 약학 조성물
JP6341777B2 (ja) * 2014-06-30 2018-06-13 リプリーズ バイオファーマシューティクス,エルエルシー 低用量デスモプレシンを含有する医薬組成物
JP2018042886A (ja) * 2016-09-16 2018-03-22 ロレアル 携帯型イオン導入デバイス

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2493155A (en) * 1947-01-09 1950-01-03 Mine Safety Appliances Co Apparatus for treating skin diseases
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4416274A (en) * 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
DE3273269D1 (en) 1981-03-06 1986-10-23 Medtronic Inc Iontophoretic electrode
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
DE3533230A1 (de) * 1985-09-18 1987-03-26 Ruediger Prof Dr Groening Transdermale arzneiformen mit verbesserter biologischer verfuegbarkeit der wirkstoffe
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery

Also Published As

Publication number Publication date
EP0252732A2 (de) 1988-01-13
EP0252732B1 (de) 1994-02-09
NZ221013A (en) 1990-09-26
JPH0626591B2 (ja) 1994-04-13
KR950008026B1 (ko) 1995-07-24
IE60941B1 (en) 1994-09-07
KR880001309A (ko) 1988-04-22
JPS6329662A (ja) 1988-02-08
ZA875002B (en) 1988-03-30
DE3789035T2 (de) 1994-07-28
DE3789035D1 (de) 1994-03-24
ES2051270T3 (es) 1994-06-16
IE861854L (en) 1988-01-10
AU7550187A (en) 1988-01-14
AU591997B2 (en) 1989-12-21
PH26087A (en) 1992-02-06
EP0252732A3 (en) 1989-03-22
CA1319578C (en) 1993-06-29
US5135480A (en) 1992-08-04

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