ATE101350T1 - Vorrichtung zur transdermalen applikation von wirksamen substanzen. - Google Patents

Vorrichtung zur transdermalen applikation von wirksamen substanzen.

Info

Publication number
ATE101350T1
ATE101350T1 AT87306033T AT87306033T ATE101350T1 AT E101350 T1 ATE101350 T1 AT E101350T1 AT 87306033 T AT87306033 T AT 87306033T AT 87306033 T AT87306033 T AT 87306033T AT E101350 T1 ATE101350 T1 AT E101350T1
Authority
AT
Austria
Prior art keywords
active substances
electrode
transdermal application
skin
contact
Prior art date
Application number
AT87306033T
Other languages
English (en)
Inventor
Yvonne Brigid Bannon
John Corish
Owen Ignatius Corrigan
Joseph G Masterson
Original Assignee
Elan Transdermal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Transdermal Ltd filed Critical Elan Transdermal Ltd
Application granted granted Critical
Publication of ATE101350T1 publication Critical patent/ATE101350T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Finger-Pressure Massage (AREA)
AT87306033T 1986-07-10 1987-07-08 Vorrichtung zur transdermalen applikation von wirksamen substanzen. ATE101350T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE185486A IE60941B1 (en) 1986-07-10 1986-07-10 Transdermal drug delivery device
EP87306033A EP0252732B1 (de) 1986-07-10 1987-07-08 Vorrichtung zur transdermalen Applikation von wirksamen Substanzen

Publications (1)

Publication Number Publication Date
ATE101350T1 true ATE101350T1 (de) 1994-02-15

Family

ID=11031295

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87306033T ATE101350T1 (de) 1986-07-10 1987-07-08 Vorrichtung zur transdermalen applikation von wirksamen substanzen.

Country Status (13)

Country Link
US (1) US5135480A (de)
EP (1) EP0252732B1 (de)
JP (1) JPH0626591B2 (de)
KR (1) KR950008026B1 (de)
AT (1) ATE101350T1 (de)
AU (1) AU591997B2 (de)
CA (1) CA1319578C (de)
DE (1) DE3789035T2 (de)
ES (1) ES2051270T3 (de)
IE (1) IE60941B1 (de)
NZ (1) NZ221013A (de)
PH (1) PH26087A (de)
ZA (1) ZA875002B (de)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US4878892A (en) * 1987-02-10 1989-11-07 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5032109A (en) * 1987-02-10 1991-07-16 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
EP0313638A4 (de) * 1987-05-15 1989-06-14 Martin H Newman Arzneimittelverabreichungssystem durch inophorese.
JP2907342B2 (ja) * 1988-01-29 1999-06-21 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア イオン滲透非侵襲的サンプリングまたは送出装置
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
ES2095929T3 (es) * 1989-10-23 1997-03-01 Theratech Inc Dispositivo iontoforetico que emplea un regulador del regimen.
US5334138A (en) * 1990-03-15 1994-08-02 North Carolina State University Method and composition for increased skin concentration of active agents by iontophoresis
DE69115471T2 (de) * 1990-03-30 1996-05-02 Alza Corp., Palo Alto, Calif. Gerät zur iontophoretischen verabreichung von medikamenten
JP3740549B2 (ja) * 1990-03-30 2006-02-01 アルザ・コーポレーション イオン侵透療法による薬剤投与の装置と方法
US5383848A (en) * 1990-04-12 1995-01-24 Gensia, Inc. Iontophoretic administration of drugs
US5362308A (en) * 1990-09-25 1994-11-08 Rutgers, The State University Of New Jersey Disposable dosage unit for iontophoresis-facilitated transdermal delivery, related devices and processes
JPH06505413A (ja) * 1991-03-11 1994-06-23 アルザ・コーポレーション イオン導入による薬物投与デバイスと同デバイスの製造方法
US5221254A (en) * 1991-04-02 1993-06-22 Alza Corporation Method for reducing sensation in iontophoretic drug delivery
US5356632A (en) * 1991-09-12 1994-10-18 S.I. Scientific Innovations Ltd. Transdermal drug delivery device
SE9102778D0 (sv) * 1991-09-25 1991-09-25 Siemens Elema Ab Implanterbar medicinsk anordning
ES2114569T3 (es) * 1991-10-16 1998-06-01 Richardson Vicks Inc Sistema mejorado de penetracion en la piel para la administracion topica mejorada de farmacos.
US5405614A (en) * 1992-04-08 1995-04-11 International Medical Associates, Inc. Electronic transdermal drug delivery system
WO1994015669A1 (en) 1992-12-31 1994-07-21 Alza Corporation Electrotransport system having flexible means
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
EP0680327B1 (de) * 1993-01-19 2004-09-15 Endorecherche Inc. Therapeutische verwendungen und verabreichungsysteme von dehydroepiandrosteron
US5427585A (en) * 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
FR2709670B1 (fr) * 1993-09-10 1995-10-20 Asulab Sa Dispositif en trois modules pour l'administration transdermique de médicaments par électrophorèse ou iontophorèse.
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
KR0134151B1 (ko) * 1994-05-23 1998-04-14 이형도 인슐린 패치
US5771890A (en) 1994-06-24 1998-06-30 Cygnus, Inc. Device and method for sampling of substances using alternating polarity
UA10911C2 (uk) * 1994-08-10 1996-12-25 Мале Впроваджувальне Підприємство "Іhтерфалл" Біосумісhий гідрогель
US5540654A (en) * 1994-09-02 1996-07-30 North Carolina State University Iontophoretic electrode
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
AU701737B2 (en) * 1995-04-07 1999-02-04 Novartis Ag Iontophoretic transdermal system for the administration of at least two substances
US6086921A (en) 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US6355025B1 (en) * 1995-06-07 2002-03-12 Alza Corporation Adjustable electrotransport drug delivery using a fixed output controller
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
EP0747092B1 (de) * 1995-06-09 2003-12-03 Hisamitsu Pharmaceutical Co., Inc. Matrix für Iontophorese
US5989409A (en) * 1995-09-11 1999-11-23 Cygnus, Inc. Method for glucose sensing
AU7286996A (en) * 1995-10-18 1997-05-07 Ciba-Geigy Ag Thermopile powered transdermal drug delivery device
EA001957B1 (ru) * 1995-12-15 2001-10-22 Вироден Фармасьютикал Холдингс (Проприетэри) Лимитед КОМПОЗИЦИЯ ДЛЯ ЛЕЧЕНИЯ СПИДа
US6175763B1 (en) 1996-03-29 2001-01-16 Alza Corporation Electrotransport drug delivery device having tactile signaling means
US5954685A (en) * 1996-05-24 1999-09-21 Cygnus, Inc. Electrochemical sensor with dual purpose electrode
WO1997048443A1 (en) * 1996-06-19 1997-12-24 Becton Dickinson And Company Iontophoretic delivery of cell adhesion inhibitors
CA2208332A1 (en) * 1996-06-20 1997-12-20 Hisamitsu Pharmaceuticals Co., Inc. Drug administration composition for iontophoresis
EP0813887A3 (de) * 1996-06-20 1999-11-03 Hisamitsu Pharmaceutical Co. Inc. Iontophoretische Vorrichtung
US6139718A (en) 1997-03-25 2000-10-31 Cygnus, Inc. Electrode with improved signal to noise ratio
ZA984649B (en) * 1997-06-13 1999-12-17 Cryopreservation Tech Cc "Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes".
US5971722A (en) * 1997-09-05 1999-10-26 Baxter International Inc Electrochemical syringe pump having a sealed storage reservoir for a charge transfer medium
KR20060098399A (ko) * 1998-06-11 2006-09-18 앙도르쉐르슈 인코포레이티드 안드로스트-5-엔-3β,17β-디올을 포함하는 약학 조성물 및그 용도
US6465445B1 (en) * 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6147102A (en) * 1999-10-26 2000-11-14 Curatek Pharmaceuticals Holding, Inc. Clonidine preparations
DE10025890A1 (de) * 2000-05-25 2001-11-29 Euro Celtique Sa Dosierung von transdermalen Arzneimittelsystemen
MY130475A (en) * 2000-08-25 2007-06-29 Contura As Polyacrylamide hydrogel and its use as an endoprosthesis
US7186419B2 (en) * 2000-08-25 2007-03-06 Contura Sa Polyacrylamide hydrogel for arthritis
US6453195B1 (en) 2001-03-19 2002-09-17 Medtronic, Inc. Closed loop drug delivery system and remote management thereof
DE60214698T2 (de) * 2001-04-30 2007-09-13 Medtronic, Inc., Minneapolis Implantierbare medizinische vorrichtung und pflastersystem
DE10137162A1 (de) * 2001-07-30 2003-02-20 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol
SE0103293D0 (sv) * 2001-10-03 2001-10-03 Painmatcher Ab Finger electrode and support structure
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US7099713B2 (en) 2002-06-28 2006-08-29 Battelle Memorial Institute Skin conduction and transport systems
AU2003282683A1 (en) * 2002-10-04 2004-05-04 Photokinetix Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
US7147955B2 (en) * 2003-01-31 2006-12-12 Societe Bic Fuel cartridge for fuel cells
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
JPWO2007023907A1 (ja) * 2005-08-24 2009-02-26 Ｔｔｉ・エルビュー株式会社 冷凍型イオントフォレーシス用電極構造体
CN101252968A (zh) 2005-09-15 2008-08-27 Tti优而美株式会社 棒式离子电渗疗装置
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
US8812112B2 (en) 2005-11-10 2014-08-19 ElectroCore, LLC Electrical treatment of bronchial constriction
EP1948301B8 (de) 2005-11-10 2014-03-12 ElectroCore LLC Elektrische stimulationsbehandlung bei bronchialkonstriktion
US8041428B2 (en) 2006-02-10 2011-10-18 Electrocore Llc Electrical stimulation treatment of hypotension
TW200800223A (en) * 2005-12-21 2008-01-01 Shire Pharmaceuticals Inc Transdermal delivery of meptazinol
US20070185431A1 (en) * 2006-02-03 2007-08-09 Kern Dale G Galvanic Current Skin Treatment
EP1984064A4 (de) * 2006-02-10 2009-11-11 Electrocore Inc Verfahren und gerät zur behandlung von anaphylaxis mit elektrischer modulation
WO2007094828A2 (en) * 2006-02-10 2007-08-23 Electrocore, Inc. Electrical stimulation treatment of hypotension
WO2008059810A1 (en) * 2006-11-14 2008-05-22 Kagoshima University Drug injecting device
BRPI0719353A2 (pt) * 2006-12-01 2014-01-07 Titi Ellebeau Inc Sistemas, dispositivos e métodos para dispositivos de energização e/ou controle, por exemplo, dispositivos de distribuição transdérmicos
US20080188778A1 (en) * 2007-02-02 2008-08-07 Yu-Yu Chen Array percutaneous therapeutic apparatus
FR2913600B1 (fr) * 2007-03-13 2011-02-25 Dbv Tech Dispositif pour l'application cutanee de substances.
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
CA2724949A1 (en) * 2007-06-27 2008-12-31 The General Hospital Corporation Method and apparatus for optical inhibition of photodynamic therapy
KR20140143461A (ko) 2007-08-06 2014-12-16 알레간 인코포레이티드 데스모프레신 약물 전달을 위한 방법 및 장치
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
CA2723806C (en) 2008-05-09 2022-05-31 Innovative Pulmonary Solutions, Inc. Systems, assemblies, and methods for treating a bronchial tree
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
SI2712622T1 (sl) 2008-05-21 2016-10-28 Ferring B.V. Orodisperzibilni dezmopresin za povečanje začetnega obdobja spanja nemotenega z nokturijo
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
US20100317635A1 (en) 2009-06-16 2010-12-16 Endorecherche, Inc. Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
PT2442821T (pt) 2009-06-18 2017-09-29 Allergan Inc Administração segura de desmopressina
JP5843777B2 (ja) 2009-10-27 2016-01-13 ホライラ， インコーポレイテッド 冷却可能なエネルギー放出アセンブリを有する送達デバイス
CN102711645B (zh) 2009-11-11 2016-12-28 赫莱拉公司 用于处理组织和控制狭窄的系统和装置
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
KR20150036825A (ko) 2010-04-13 2015-04-07 나지브 바불 1-메틸-2''-6''-피페콜옥실리디드의 피부 약제학적 조성물 및 사용 방법
KR20160088947A (ko) 2010-06-16 2016-07-26 앙도르쉐르슈 인코포레이티드 에스트로겐-관련 질병의 치료 또는 예방 방법
ES1073640Y (es) * 2010-06-22 2011-04-11 De La Iglesia Marta Perez Pulsera de administracion transdermica de nicotina
US9433459B2 (en) 2010-07-13 2016-09-06 Zoll Medical Corporation Deposit ablation within and external to circulatory systems
EP2903684A4 (de) * 2012-10-01 2016-06-29 Zoll Medical Corp Ablagerungsentfernung innerhalb und ausserhalb von kreislaufsystemen
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US9744177B2 (en) 2014-03-10 2017-08-29 Endorecherche, Inc. Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
KR20150144209A (ko) * 2014-06-16 2015-12-24 훼링 비.브이. 안정화된 데스모프레신 또는 이의 약학적으로 허용가능한 염을 함유 약학 조성물
JP6341777B2 (ja) * 2014-06-30 2018-06-13 リプリーズ バイオファーマシューティクス，エルエルシー 低用量デスモプレシンを含有する医薬組成物
JP2018042886A (ja) * 2016-09-16 2018-03-22 ロレアル 携帯型イオン導入デバイス

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2493155A (en) * 1947-01-09 1950-01-03 Mine Safety Appliances Co Apparatus for treating skin diseases
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4416274A (en) * 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
DE3273269D1 (en) 1981-03-06 1986-10-23 Medtronic Inc Iontophoretic electrode
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
DE3533230A1 (de) * 1985-09-18 1987-03-26 Ruediger Prof Dr Groening Transdermale arzneiformen mit verbesserter biologischer verfuegbarkeit der wirkstoffe
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery

Also Published As

Publication number Publication date
ES2051270T3 (es) 1994-06-16
IE861854L (en) 1988-01-10
JPH0626591B2 (ja) 1994-04-13
DE3789035T2 (de) 1994-07-28
CA1319578C (en) 1993-06-29
EP0252732A2 (de) 1988-01-13
KR880001309A (ko) 1988-04-22
EP0252732A3 (en) 1989-03-22
EP0252732B1 (de) 1994-02-09
DE3789035D1 (de) 1994-03-24
AU7550187A (en) 1988-01-14
KR950008026B1 (ko) 1995-07-24
PH26087A (en) 1992-02-06
US5135480A (en) 1992-08-04
ZA875002B (en) 1988-03-30
IE60941B1 (en) 1994-09-07
AU591997B2 (en) 1989-12-21
NZ221013A (en) 1990-09-26
JPS6329662A (ja) 1988-02-08

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Legal Events

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