ATA497575A - Verfahren zur herstellung von neuen benzodiazepin-derivaten - Google Patents

Verfahren zur herstellung von neuen benzodiazepin-derivaten

Info

Publication number
ATA497575A
ATA497575A AT497575A AT497575A ATA497575A AT A497575 A ATA497575 A AT A497575A AT 497575 A AT497575 A AT 497575A AT 497575 A AT497575 A AT 497575A AT A497575 A ATA497575 A AT A497575A
Authority
AT
Austria
Prior art keywords
producing new
benzodiazepine derivatives
new benzodiazepine
derivatives
producing
Prior art date
Application number
AT497575A
Other languages
English (en)
Other versions
AT347468B (de
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA497575A publication Critical patent/ATA497575A/de
Application granted granted Critical
Publication of AT347468B publication Critical patent/AT347468B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT497575A 1974-06-28 1975-06-27 Verfahren zur herstellung von neuen benzodiazepin-derivaten AT347468B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH892674A CH602672A5 (de) 1974-06-28 1974-06-28

Publications (2)

Publication Number Publication Date
ATA497575A true ATA497575A (de) 1978-05-15
AT347468B AT347468B (de) 1978-12-27

Family

ID=4346371

Family Applications (1)

Application Number Title Priority Date Filing Date
AT497575A AT347468B (de) 1974-06-28 1975-06-27 Verfahren zur herstellung von neuen benzodiazepin-derivaten

Country Status (18)

Country Link
US (1) US4046890A (de)
JP (1) JPS6050786B2 (de)
AT (1) AT347468B (de)
BE (1) BE830722A (de)
CA (1) CA1048495A (de)
CH (1) CH602672A5 (de)
DE (1) DE2526869A1 (de)
DK (1) DK293375A (de)
FR (1) FR2276055A1 (de)
GB (1) GB1444529A (de)
IE (1) IE41481B1 (de)
IL (1) IL47263A (de)
KE (1) KE3004A (de)
LU (1) LU72837A1 (de)
NL (1) NL7507682A (de)
PH (1) PH12433A (de)
SE (1) SE421126B (de)
ZA (1) ZA752965B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2834637A1 (fr) * 2002-01-15 2003-07-18 Centre Nat Rech Scient Utilisation d'une nouvelle classe de medicaments pour le traitement de maladies parasitaires
WO2006060736A2 (en) * 2004-12-03 2006-06-08 The Children's Hospital Of Philadelphia A composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121076A (en) * 1964-02-11 Benzodiazepinones and processes
US3123529A (en) * 1964-03-03 -parenteral -compoiaxions -containing
US3116203A (en) * 1962-03-14 1963-12-31 Hoffmann La Roche Oleaginous systems
US3248223A (en) * 1962-04-11 1966-04-26 Hoffmann La Roche Animal feeds and methods
GB1063891A (en) * 1964-01-14 1967-04-05 Delmar Chem Method for preparation of benzodiazepinones
FR1462887A (fr) * 1966-01-06 1966-12-16 Hoffmann La Roche Procédé pour la préparation de dérivés de benzodiazépine
CH554349A (de) * 1971-03-17 1974-09-30 Crc Ricerca Chim Verfahren zur herstellung von optisch aktiven 1,3-dihydro-2h-1,4-benzodiazepin-2-onen.
US3998811A (en) * 1971-03-17 1976-12-21 Crc Compagnia Di Recerca Chimica S.A. Optically active 1,4-benzodiazepines and process for the preparation thereof

Also Published As

Publication number Publication date
SE7507186L (sv) 1975-12-29
JPS6050786B2 (ja) 1985-11-11
FR2276055B1 (de) 1979-08-17
NL7507682A (nl) 1975-12-30
CH602672A5 (de) 1978-07-31
IE41481B1 (en) 1980-01-16
LU72837A1 (de) 1977-03-07
CA1048495A (en) 1979-02-13
BE830722A (fr) 1975-12-29
FR2276055A1 (fr) 1976-01-23
JPS5123282A (de) 1976-02-24
DK293375A (da) 1975-12-29
IL47263A0 (en) 1975-07-28
SE421126B (sv) 1981-11-30
PH12433A (en) 1979-02-22
AU8110475A (en) 1976-11-18
ZA752965B (en) 1976-04-28
DE2526869A1 (de) 1976-01-15
GB1444529A (en) 1976-08-04
IL47263A (en) 1979-03-12
IE41481L (en) 1975-12-28
US4046890A (en) 1977-09-06
KE3004A (en) 1979-12-14
AT347468B (de) 1978-12-27

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee