AT372943B - Verfahren zur herstellung des neuen vitamin d3derivates 1alpha,25,26-trihydroxycholecalciferol - Google Patents
Verfahren zur herstellung des neuen vitamin d3derivates 1alpha,25,26-trihydroxycholecalciferolInfo
- Publication number
- AT372943B AT372943B AT0459980A AT459980A AT372943B AT 372943 B AT372943 B AT 372943B AT 0459980 A AT0459980 A AT 0459980A AT 459980 A AT459980 A AT 459980A AT 372943 B AT372943 B AT 372943B
- Authority
- AT
- Austria
- Prior art keywords
- trihydroxycholecalciferol
- 1alpha
- derivates
- producing
- new vitamin
- Prior art date
Links
- 239000003050 1alpha,25,26-trihydroxy-cholecalciferol Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/16—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Nutrition Science (AREA)
- Rheumatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH834679A CH644100A5 (de) | 1979-09-14 | 1979-09-14 | Cholecalciferolderivate. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA459980A ATA459980A (de) | 1983-04-15 |
| AT372943B true AT372943B (de) | 1983-11-25 |
Family
ID=4338917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0459980A AT372943B (de) | 1979-09-14 | 1980-09-12 | Verfahren zur herstellung des neuen vitamin d3derivates 1alpha,25,26-trihydroxycholecalciferol |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4407754A (de) |
| JP (1) | JPS5651447A (de) |
| AT (1) | AT372943B (de) |
| BE (1) | BE885204A (de) |
| CH (1) | CH644100A5 (de) |
| DE (1) | DE3034722A1 (de) |
| FR (1) | FR2468587A1 (de) |
| GB (1) | GB2060642B (de) |
| IT (1) | IT1131777B (de) |
| NL (1) | NL8005064A (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617297A (en) * | 1982-02-12 | 1986-10-14 | Hoffmann-La Roche Inc. | Method of treating disease states by the administration of 1α,25,26-trihydroxycholecalciferol |
| EP0086350A3 (de) * | 1982-02-12 | 1984-11-28 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung von Cholesterinderivaten |
| ZA83923B (en) * | 1982-02-12 | 1983-11-30 | Hoffmann La Roche | Use of cholecalciferol derivatives |
| US5120722A (en) * | 1984-02-08 | 1992-06-09 | Hoffmann-La Roche Inc. | Trihydroxy-cholecacliferol and trihydroxy-ergocalciferol for treating leukemia |
| DE3854089T2 (de) * | 1988-07-05 | 1995-11-02 | Kuraray Co | Steroid-verbindungen. |
| CN101381389B (zh) * | 2008-09-29 | 2011-05-25 | 浙江工业大学 | 5,7-双烯甾类化合物的化学合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3739001A (en) * | 1971-10-22 | 1973-06-12 | Wisconsin Alumni Res Found | 25,26-dihydroxycholecalciferol |
| US4204995A (en) * | 1978-03-15 | 1980-05-27 | Hoffmann-La Roche Inc. | Cholestane derivatives |
| EP0019059B1 (de) * | 1979-05-18 | 1982-12-29 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung von Cholestenderivaten und neue Zwischenprodukte in deren Herstellung |
| US4265822A (en) * | 1979-09-10 | 1981-05-05 | Wisconsin Alumni Research Foundation | Process for preparing 1-hydroxylated vitamin D compounds from 5,6-trans-vitamin D compounds |
-
1979
- 1979-09-14 CH CH834679A patent/CH644100A5/de not_active IP Right Cessation
-
1980
- 1980-07-28 IT IT23753/80A patent/IT1131777B/it active
- 1980-09-08 NL NL8005064A patent/NL8005064A/nl not_active Application Discontinuation
- 1980-09-11 JP JP12537280A patent/JPS5651447A/ja active Granted
- 1980-09-12 AT AT0459980A patent/AT372943B/de not_active IP Right Cessation
- 1980-09-12 GB GB8029544A patent/GB2060642B/en not_active Expired
- 1980-09-12 FR FR8019721A patent/FR2468587A1/fr active Granted
- 1980-09-12 BE BE0/202077A patent/BE885204A/fr not_active IP Right Cessation
- 1980-09-15 DE DE19803034722 patent/DE3034722A1/de not_active Ceased
-
1982
- 1982-03-12 US US06/357,438 patent/US4407754A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CH644100A5 (de) | 1984-07-13 |
| FR2468587B1 (de) | 1984-10-19 |
| NL8005064A (nl) | 1981-03-17 |
| US4407754A (en) | 1983-10-04 |
| GB2060642B (en) | 1983-11-30 |
| ATA459980A (de) | 1983-04-15 |
| DE3034722A1 (de) | 1981-04-02 |
| GB2060642A (en) | 1981-05-07 |
| JPS5651447A (en) | 1981-05-09 |
| IT1131777B (it) | 1986-06-25 |
| IT8023753A0 (it) | 1980-07-28 |
| FR2468587A1 (fr) | 1981-05-08 |
| BE885204A (fr) | 1981-03-12 |
| JPH0144695B2 (de) | 1989-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |