AT361931B - Verfahren zur herstellung neuer benzyl- pyrimidine und ihrer salze - Google Patents
Verfahren zur herstellung neuer benzyl- pyrimidine und ihrer salzeInfo
- Publication number
- AT361931B AT361931B AT487478A AT487478A AT361931B AT 361931 B AT361931 B AT 361931B AT 487478 A AT487478 A AT 487478A AT 487478 A AT487478 A AT 487478A AT 361931 B AT361931 B AT 361931B
- Authority
- AT
- Austria
- Prior art keywords
- salts
- producing new
- benzyl pyrimidine
- new benzyl
- pyrimidine
- Prior art date
Links
- OOLOAWZLPBDRJQ-UHFFFAOYSA-N 2-benzylpyrimidine Chemical compound N=1C=CC=NC=1CC1=CC=CC=C1 OOLOAWZLPBDRJQ-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772730467 DE2730467A1 (de) | 1977-07-06 | 1977-07-06 | Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA487478A ATA487478A (de) | 1980-09-15 |
| AT361931B true AT361931B (de) | 1981-04-10 |
Family
ID=6013252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT487478A AT361931B (de) | 1977-07-06 | 1978-07-05 | Verfahren zur herstellung neuer benzyl- pyrimidine und ihrer salze |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4279899A (de) |
| EP (1) | EP0000334B1 (de) |
| JP (1) | JPS5416482A (de) |
| AR (1) | AR223465A1 (de) |
| AT (1) | AT361931B (de) |
| AU (1) | AU515661B2 (de) |
| CA (1) | CA1102324A (de) |
| DE (2) | DE2730467A1 (de) |
| DK (1) | DK142578C (de) |
| FI (1) | FI782173A7 (de) |
| HU (1) | HU179407B (de) |
| IE (1) | IE781308L (de) |
| IL (1) | IL55018A (de) |
| IN (1) | IN149577B (de) |
| IT (1) | IT7825220A0 (de) |
| NO (1) | NO782340L (de) |
| ZA (1) | ZA783873B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4438267A (en) * | 1980-11-11 | 1984-03-20 | Daluge Susan M | Monoheteroring compounds and their use |
| DE3045720A1 (de) * | 1980-12-04 | 1982-07-08 | Basf Ag, 6700 Ludwigshafen | N-pyrimidinyl-carbaminsaeureester, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| HU186413B (en) * | 1981-06-26 | 1985-07-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing 2,4-diamino-5-bracket-3-comma above,4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine |
| HU187370B (en) * | 1981-06-26 | 1985-12-28 | Egyt Gyogyszervegyeszeti Gyar | Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine |
| EP1438053B1 (de) * | 2001-10-17 | 2008-09-10 | Boehringer Ingelheim Pharma GmbH & Co.KG | Pyrimidinderivate, arzneimittel enthaltend diese verbindungen, deren verwendung und verfahren zu ihrer herstellung |
| AR081626A1 (es) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
| WO2011133920A1 (en) | 2010-04-23 | 2011-10-27 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
| AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3049544A (en) * | 1962-08-14 | Method for the preparation of | ||
| US2723975A (en) * | 1952-04-03 | 1955-11-15 | Nepera Chemical Co Inc | 2, 4-di-piperidino-5-benzylpyrimidine |
| US2649449A (en) * | 1952-04-04 | 1953-08-18 | Nepera Chemical Co Inc | 2-cyclohexylamino-4-amino-5-benzylpyrimidine |
| CH376115A (de) * | 1957-12-06 | 1964-03-31 | Ciba Geigy | Verfahren zur Herstellung neuer substituierter Pyrimidine |
| US3515783A (en) | 1967-10-20 | 1970-06-02 | Hoffmann La Roche | Antibacterial composition containing 5-methyl - 3 - sulfanilamidoisoxazole and trimethoxybenzyl pyrimidine |
| US4115650A (en) * | 1976-11-17 | 1978-09-19 | Hoffmann-La Roche Inc. | Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines |
-
1977
- 1977-07-06 DE DE19772730467 patent/DE2730467A1/de not_active Withdrawn
-
1978
- 1978-06-16 DE DE7878100180T patent/DE2860928D1/de not_active Expired
- 1978-06-16 EP EP78100180A patent/EP0000334B1/de not_active Expired
- 1978-06-27 IL IL55018A patent/IL55018A/xx unknown
- 1978-06-27 US US05/919,505 patent/US4279899A/en not_active Expired - Lifetime
- 1978-06-29 IE IE781308A patent/IE781308L/xx unknown
- 1978-06-30 IT IT7825220A patent/IT7825220A0/it unknown
- 1978-06-30 AU AU37644/78A patent/AU515661B2/en not_active Expired
- 1978-07-04 AR AR272831A patent/AR223465A1/es active
- 1978-07-04 HU HU78BA3672A patent/HU179407B/hu unknown
- 1978-07-04 CA CA306,732A patent/CA1102324A/en not_active Expired
- 1978-07-05 DK DK303178A patent/DK142578C/da active
- 1978-07-05 AT AT487478A patent/AT361931B/de not_active IP Right Cessation
- 1978-07-05 ZA ZA00783873A patent/ZA783873B/xx unknown
- 1978-07-05 FI FI782173A patent/FI782173A7/fi not_active Application Discontinuation
- 1978-07-05 NO NO782340A patent/NO782340L/no unknown
- 1978-07-06 JP JP8153078A patent/JPS5416482A/ja active Pending
- 1978-07-06 IN IN747/CAL/78A patent/IN149577B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATA487478A (de) | 1980-09-15 |
| NO782340L (no) | 1979-01-09 |
| US4279899A (en) | 1981-07-21 |
| DK142578B (da) | 1980-11-24 |
| IE781308L (en) | 1979-01-06 |
| AU515661B2 (en) | 1981-04-16 |
| DE2730467A1 (de) | 1979-01-18 |
| IL55018A0 (en) | 1978-08-31 |
| HU179407B (en) | 1982-10-28 |
| DK142578C (da) | 1981-07-20 |
| FI782173A7 (fi) | 1979-01-07 |
| AR223465A1 (es) | 1981-08-31 |
| EP0000334B1 (de) | 1981-08-12 |
| IN149577B (de) | 1982-01-30 |
| EP0000334A1 (de) | 1979-01-24 |
| AU3764478A (en) | 1980-01-03 |
| JPS5416482A (en) | 1979-02-07 |
| DK303178A (da) | 1979-01-07 |
| CA1102324A (en) | 1981-06-02 |
| IL55018A (en) | 1983-03-31 |
| IT7825220A0 (it) | 1978-06-30 |
| ZA783873B (en) | 1979-08-29 |
| DE2860928D1 (en) | 1981-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |