AT333448B - Verfahren zur herstellung von insulin, insulin-analogen und -derivaten - Google Patents

Verfahren zur herstellung von insulin, insulin-analogen und -derivaten

Info

Publication number
AT333448B
AT333448B AT916273A AT916273A AT333448B AT 333448 B AT333448 B AT 333448B AT 916273 A AT916273 A AT 916273A AT 916273 A AT916273 A AT 916273A AT 333448 B AT333448 B AT 333448B
Authority
AT
Austria
Prior art keywords
insulin
derivatives
manufacturing
analogs
insulin analogs
Prior art date
Application number
AT916273A
Other languages
English (en)
Other versions
ATA916273A (de
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722253297 external-priority patent/DE2253297C3/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ATA916273A publication Critical patent/ATA916273A/de
Application granted granted Critical
Publication of AT333448B publication Critical patent/AT333448B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT916273A 1972-10-31 1973-10-30 Verfahren zur herstellung von insulin, insulin-analogen und -derivaten AT333448B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722253297 DE2253297C3 (de) 1972-10-31 Zwischenprodukt zur Herstellung von Insulin, Insulin-Analogen und -Derivaten und Verfahren zur Herstellung von Insulin, Insulin-Analogen und -Derivaten

Publications (2)

Publication Number Publication Date
ATA916273A ATA916273A (de) 1976-03-15
AT333448B true AT333448B (de) 1976-11-25

Family

ID=5860480

Family Applications (1)

Application Number Title Priority Date Filing Date
AT916273A AT333448B (de) 1972-10-31 1973-10-30 Verfahren zur herstellung von insulin, insulin-analogen und -derivaten

Country Status (9)

Country Link
US (1) US3884897A (de)
JP (1) JPS528836B2 (de)
AT (1) AT333448B (de)
AU (1) AU6198173A (de)
BE (1) BE806832R (de)
DD (1) DD113352A6 (de)
FR (1) FR2204617B2 (de)
GB (1) GB1453865A (de)
NL (1) NL7314766A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428412A1 (de) * 1974-06-12 1976-01-15 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten
USRE32015E (en) * 1974-06-12 1985-10-29 Hoechst Aktiengesellschaft Process for the manufacture of insulin, analogs and derivatives thereof
DE2439296A1 (de) * 1974-08-16 1976-02-26 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten
JPS5939422B2 (ja) * 1975-02-15 1984-09-22 イ−ライ リリ− アンド カンパニ− インシユリンの精製法
JPS5939421B2 (ja) * 1975-02-15 1984-09-22 イ−ライ リリ− アンド カンパニ− インシユリンの精製方法
JPS58182852U (ja) * 1982-05-31 1983-12-06 小島プレス工業株式会社 コンソ−ルボツクス
DE3327928A1 (de) * 1983-08-03 1985-02-21 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
JP2606915B2 (ja) * 1987-02-25 1997-05-07 ノボ ノルディスク アクティーゼルスカブ 新規インシュリン誘導体
US5646242A (en) * 1994-11-17 1997-07-08 Eli Lilly And Company Selective acylation of epsilon-amino groups
US5631347A (en) * 1995-06-07 1997-05-20 Eli Lilly And Company Reducing gelation of a fatty acid-acylated protein
US5700904A (en) * 1995-06-07 1997-12-23 Eli Lilly And Company Preparation of an acylated protein powder
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3420810A (en) * 1966-10-25 1969-01-07 Atomic Energy Commission Process for joining the a and b chains of insulin
IE36225B1 (en) * 1971-01-28 1976-09-15 Nat Res Dev Improvements relating to insulin derivatives
BE795238A (fr) * 1972-02-09 1973-08-09 Schering Ag Derives d'insuline reticules de maniere intramoleculaire, leur procede de preparation et leur utilisation

Also Published As

Publication number Publication date
FR2204617B2 (de) 1978-12-01
JPS528836B2 (de) 1977-03-11
GB1453865A (en) 1976-10-27
FR2204617A2 (de) 1974-05-24
DD113352A6 (de) 1975-06-12
BE806832R (fr) 1974-04-30
DE2253297B2 (de) 1975-11-20
NL7314766A (de) 1974-05-02
AU6198173A (en) 1975-05-01
ATA916273A (de) 1976-03-15
JPS4980092A (de) 1974-08-02
US3884897A (en) 1975-05-20
DE2253297A1 (de) 1974-05-30

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee