AT305250B - Process for the preparation of new 1-hydroxyphenyl-1-hydroxy-2- (3-aryl-3-hydroxypropyl) -aminoethanes and of their acid addition salts - Google Patents

Process for the preparation of new 1-hydroxyphenyl-1-hydroxy-2- (3-aryl-3-hydroxypropyl) -aminoethanes and of their acid addition salts

Info

Publication number
AT305250B
AT305250B AT54671A AT54671A AT305250B AT 305250 B AT305250 B AT 305250B AT 54671 A AT54671 A AT 54671A AT 54671 A AT54671 A AT 54671A AT 305250 B AT305250 B AT 305250B
Authority
AT
Austria
Prior art keywords
aminoethanes
hydroxyphenyl
hydroxypropyl
aryl
hydroxy
Prior art date
Application number
AT54671A
Other languages
German (de)
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to DE19712164505 priority Critical patent/DE2164505A1/en
Application granted granted Critical
Publication of AT305250B publication Critical patent/AT305250B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/56Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
    • C07C215/58Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C07C215/62Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/72Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT54671A 1970-02-25 1971-01-22 Process for the preparation of new 1-hydroxyphenyl-1-hydroxy-2- (3-aryl-3-hydroxypropyl) -aminoethanes and of their acid addition salts AT305250B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19712164505 DE2164505A1 (en) 1971-01-22 1971-12-24 Cardioactive hydroxyphenyl-aminoethanol derivs - from o - and n-protected derivs by catalytic hydrogenation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702008654 DE2008654A1 (en) 1970-02-25 1970-02-25 Ammoathanoldenvate

Publications (1)

Publication Number Publication Date
AT305250B true AT305250B (en) 1973-02-12

Family

ID=5763256

Family Applications (3)

Application Number Title Priority Date Filing Date
AT204672A AT306707B (en) 1970-02-25 1971-01-22 Process for the preparation of new 1-hydroxyphenyl- -1-hydroxy-2- (3'-aryl-3'-hydroxypropyl) aminoethanes and their acid addition salts
AT204572A AT306706B (en) 1970-02-25 1971-01-22 Process for the preparation of new 1-hydroxyphenyl- -1-hydroxy-2- (3'-aryl-3'-hydroxypropyl) aminoethanes and their acid addition salts
AT54671A AT305250B (en) 1970-02-25 1971-01-22 Process for the preparation of new 1-hydroxyphenyl-1-hydroxy-2- (3-aryl-3-hydroxypropyl) -aminoethanes and of their acid addition salts

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT204672A AT306707B (en) 1970-02-25 1971-01-22 Process for the preparation of new 1-hydroxyphenyl- -1-hydroxy-2- (3'-aryl-3'-hydroxypropyl) aminoethanes and their acid addition salts
AT204572A AT306706B (en) 1970-02-25 1971-01-22 Process for the preparation of new 1-hydroxyphenyl- -1-hydroxy-2- (3'-aryl-3'-hydroxypropyl) aminoethanes and their acid addition salts

Country Status (18)

Country Link
AT (3) AT306707B (en)
BE (1) BE763408A (en)
BG (3) BG18856A3 (en)
CH (4) CH568269A5 (en)
CS (3) CS166748B2 (en)
DE (1) DE2008654A1 (en)
ES (3) ES388561A1 (en)
FR (1) FR2081541B1 (en)
GB (1) GB1340407A (en)
IE (1) IE34970B1 (en)
IL (1) IL36269A (en)
NL (1) NL7102432A (en)
NO (1) NO131983C (en)
PL (3) PL82843B1 (en)
RO (3) RO62244A (en)
SE (1) SE377561B (en)
SU (2) SU421181A3 (en)
ZA (1) ZA711204B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA791403B (en) * 1978-04-10 1980-05-28 Draco Ab Composition of matter
FI70205C (en) * 1978-05-17 1986-09-15 Degussa FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA L- / 3-HYDROXI-3-PHENYLPROPYL- (2) / - / 3-OXO-PROPYL / AMINER
US4853381A (en) * 1984-04-17 1989-08-01 Glaxo Group Limited Ethanolamine compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE630296A (en) * 1962-03-31

Also Published As

Publication number Publication date
CH568271A5 (en) 1975-10-31
DE2008654A1 (en) 1971-09-09
RO58559A (en) 1975-09-15
IL36269A0 (en) 1971-04-28
RO60182A (en) 1976-08-15
BG18856A3 (en) 1975-03-20
ES396174A1 (en) 1974-04-01
IE34970L (en) 1971-08-25
BG18855A3 (en) 1975-03-20
ZA711204B (en) 1972-10-25
AT306706B (en) 1973-04-25
CH568268A5 (en) 1975-10-31
NO131983C (en) 1975-09-03
BE763408A (en) 1971-08-24
ES396175A1 (en) 1974-04-01
NL7102432A (en) 1971-08-27
FR2081541A1 (en) 1971-12-03
PL82843B1 (en) 1975-10-31
PL84268B1 (en) 1976-03-31
GB1340407A (en) 1973-12-12
CH568269A5 (en) 1975-10-31
SU424349A3 (en) 1974-04-15
SE377561B (en) 1975-07-14
CS166750B2 (en) 1976-03-29
IE34970B1 (en) 1975-10-01
RO62244A (en) 1977-08-15
PL84395B1 (en) 1976-03-31
NO131983B (en) 1975-05-26
CS166748B2 (en) 1976-03-29
FR2081541B1 (en) 1975-01-17
CH568270A5 (en) 1975-10-31
IL36269A (en) 1974-01-14
ES388561A1 (en) 1973-05-16
BG19130A3 (en) 1975-04-30
CS166749B2 (en) 1976-03-29
AT306707B (en) 1973-04-25
SU421181A3 (en) 1974-03-25
SU404229A3 (en) 1973-10-26

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Legal Events

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ELJ Ceased due to non-payment of the annual fee