AT297677B - Verfahren zur Herstellung und Isolierung von neuem N-Carboxyasparaginsäureanhydrid - Google Patents

Verfahren zur Herstellung und Isolierung von neuem N-Carboxyasparaginsäureanhydrid

Info

Publication number
AT297677B
AT297677B AT729270A AT729270A AT297677B AT 297677 B AT297677 B AT 297677B AT 729270 A AT729270 A AT 729270A AT 729270 A AT729270 A AT 729270A AT 297677 B AT297677 B AT 297677B
Authority
AT
Austria
Prior art keywords
carboxyaspartic
anhydride
isolation
preparation
new
Prior art date
Application number
AT729270A
Other languages
German (de)
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of AT297677B publication Critical patent/AT297677B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C07K1/086—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695—Corticotropin [ACTH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Arc Welding In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT729270A 1965-07-02 1966-06-28 Verfahren zur Herstellung und Isolierung von neuem N-Carboxyasparaginsäureanhydrid AT297677B (de)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US46931065A 1965-07-02 1965-07-02
US50498265A 1965-10-24 1965-10-24
US50497865A 1965-10-24 1965-10-24
US53856066A 1966-03-30 1966-03-30
US53854266A 1966-03-30 1966-03-30
US54435866A 1966-04-22 1966-04-22
US54438066A 1966-04-22 1966-04-22
US54586266A 1966-04-28 1966-04-28
US54585566A 1966-04-28 1966-04-28
US54585766A 1966-04-28 1966-04-28
GB27965/66A GB1158721A (en) 1965-07-02 1966-06-22 Peptide synthesis

Publications (1)

Publication Number Publication Date
AT297677B true AT297677B (de) 1972-04-10

Family

ID=27581645

Family Applications (4)

Application Number Title Priority Date Filing Date
AT729270A AT297677B (de) 1965-07-02 1966-06-28 Verfahren zur Herstellung und Isolierung von neuem N-Carboxyasparaginsäureanhydrid
AT735669A AT289105B (de) 1965-07-02 1966-06-28 Verfahren zur Herstellung von neuen Hydrobromiden und Hydrochloriden
AT735569A AT290490B (de) 1965-07-02 1966-06-28 Verfahren zur Herstellung von neuem N-Carboxyasparaginanhydrid oder- N-Carboxyglutaminanhydrid
AT618466A AT307630B (de) 1965-07-02 1966-06-28 Verfahren zur Synthese von Polypeptiden

Family Applications After (3)

Application Number Title Priority Date Filing Date
AT735669A AT289105B (de) 1965-07-02 1966-06-28 Verfahren zur Herstellung von neuen Hydrobromiden und Hydrochloriden
AT735569A AT290490B (de) 1965-07-02 1966-06-28 Verfahren zur Herstellung von neuem N-Carboxyasparaginanhydrid oder- N-Carboxyglutaminanhydrid
AT618466A AT307630B (de) 1965-07-02 1966-06-28 Verfahren zur Synthese von Polypeptiden

Country Status (13)

Country Link
US (3) US3435046A (en:Method)
JP (1) JPS4737921B1 (en:Method)
AT (4) AT297677B (en:Method)
BR (1) BR6680930D0 (en:Method)
CH (1) CH495956A (en:Method)
DE (8) DE1793597A1 (en:Method)
DK (1) DK138369B (en:Method)
FI (1) FI48184C (en:Method)
GB (7) GB1158725A (en:Method)
IL (6) IL34878A (en:Method)
NO (1) NO128326B (en:Method)
SE (4) SE349038B (en:Method)
YU (1) YU31197B (en:Method)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1675379B1 (de) * 1968-01-13 1972-03-09 Roesinger Heinz Rollringdichtung fuer muffenrohr verbindungen
NL7002228A (en:Method) * 1970-02-18 1971-08-20
FR2569111B1 (fr) * 1984-08-16 1987-04-17 Rhone Poulenc Sante Nouveaux medicaments contenant des tripeptides
DE3542784A1 (de) * 1985-12-04 1987-06-11 Hella Kg Hueck & Co Scheinwerfer fuer kraftfahrzeuge
JPH0383990A (ja) * 1989-08-28 1991-04-09 Nippon Paint Co Ltd オキサゾリジン化合物
IN184759B (en:Method) * 1997-07-22 2000-09-23 Kaneka Corp
WO2000005247A1 (en) * 1998-07-21 2000-02-03 Kaneka Corporation Method for crystallizing maleic acid salt of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanyl-l-proline
DE19936976A1 (de) 1999-08-05 2001-02-08 Emil Siegwart Flanschverbindung von Rohren, insbesondere Luftleitungsrohren

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2993053A (en) * 1961-07-18 Production of n-carboxy-a-amino
US2716647A (en) * 1952-07-30 1955-08-30 Monsanto Chemicals N-carboxy anhydride of alpha-amino acids

Also Published As

Publication number Publication date
DE1795528A1 (de) 1972-01-13
DE1795519A1 (de) 1972-01-13
GB1158725A (en) 1969-07-16
DK138369B (da) 1978-08-21
DE1795521A1 (de) 1972-01-13
GB1158722A (en) 1969-07-16
NO128326B (en:Method) 1973-10-29
IL34878A (en) 1971-02-25
GB1158724A (en) 1969-07-16
SE364716B (en:Method) 1974-03-04
US3435046A (en) 1969-03-25
SE349038B (en:Method) 1972-09-18
IL34880A (en) 1970-11-30
US3459760A (en) 1969-08-05
IL34879A (en) 1971-03-24
JPS4737921B1 (en:Method) 1972-09-25
GB1158726A (en) 1969-07-16
IL34876A (en) 1971-02-25
FI48184C (fi) 1974-07-10
SE347512B (en:Method) 1972-08-07
IL25974A (en) 1971-02-25
CH495956A (de) 1970-09-15
DE1795524A1 (de) 1972-01-13
AT289105B (de) 1971-04-13
DE1795522A1 (de) 1972-01-13
GB1158721A (en) 1969-07-16
GB1158727A (en) 1969-07-16
FI48184B (en:Method) 1974-04-01
GB1158723A (en) 1969-07-16
DE1795523A1 (de) 1972-01-13
US3467667A (en) 1969-09-16
DE1795529A1 (de) 1972-01-13
DE1793597A1 (de) 1972-03-16
IL34877A (en) 1971-03-24
YU31197B (en) 1973-02-28
DK138369C (en:Method) 1979-02-05
AT307630B (de) 1973-05-25
SE345998B (en:Method) 1972-06-19
AT290490B (de) 1971-06-11
BR6680930D0 (pt) 1973-11-13

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