AT292675B - Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen - Google Patents
Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren SäureadditionssalzenInfo
- Publication number
- AT292675B AT292675B AT879670A AT879670A AT292675B AT 292675 B AT292675 B AT 292675B AT 879670 A AT879670 A AT 879670A AT 879670 A AT879670 A AT 879670A AT 292675 B AT292675 B AT 292675B
- Authority
- AT
- Austria
- Prior art keywords
- alkylaminopropanes
- phenoxy
- hydroxy
- preparation
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1643262A DE1643262C3 (de) | 1967-12-13 | 1967-12-13 | i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
AT292675B true AT292675B (de) | 1971-09-10 |
Family
ID=5684274
Family Applications (13)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT1216668A AT292670B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879570A AT292674B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879770A AT292676B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879970A AT298459B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879870A AT292677B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT880270A AT292680B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879470A AT294799B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879370A AT292673B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT880170A AT292679B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT880070A AT292678B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879670A AT292675B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT595771A AT298463B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT08803/70A AT292681B (de) | 1967-12-13 | 1970-12-13 | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy-3-alkylaminopropanen und deren saeureadditionssalzen |
Family Applications Before (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT1216668A AT292670B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879570A AT292674B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879770A AT292676B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879970A AT298459B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879870A AT292677B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT880270A AT292680B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879470A AT294799B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT879370A AT292673B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT880170A AT292679B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT880070A AT292678B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT595771A AT298463B (de) | 1967-12-13 | 1968-12-13 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen |
AT08803/70A AT292681B (de) | 1967-12-13 | 1970-12-13 | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy-3-alkylaminopropanen und deren saeureadditionssalzen |
Country Status (21)
Country | Link |
---|---|
US (1) | US3872147A (xx) |
JP (1) | JPS5220457B1 (xx) |
AT (13) | AT292670B (xx) |
BE (1) | BE725490A (xx) |
BG (9) | BG17298A3 (xx) |
BR (1) | BR6804840D0 (xx) |
CA (1) | CA954528A (xx) |
CH (2) | CH532015A (xx) |
DE (1) | DE1643262C3 (xx) |
DK (1) | DK131029B (xx) |
ES (11) | ES361189A1 (xx) |
FI (1) | FI49497C (xx) |
FR (2) | FR1596100A (xx) |
GB (1) | GB1260866A (xx) |
HU (1) | HU162734B (xx) |
IE (1) | IE32758B1 (xx) |
IL (1) | IL31266A (xx) |
NL (3) | NL146709B (xx) |
PH (1) | PH9266A (xx) |
SE (1) | SE367396B (xx) |
YU (12) | YU33949B (xx) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
US4086272A (en) * | 1970-07-18 | 1978-04-25 | Pfizer Inc. | Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants |
US3998874A (en) * | 1971-03-23 | 1976-12-21 | Gist-Brocades N.V. | Phenylene di-ethers |
US4038414A (en) * | 1972-06-08 | 1977-07-26 | Ciba-Geigy Corporation | Amines and processes for their manufacture |
DE2309887C2 (de) * | 1973-02-28 | 1983-11-10 | C.H. Boehringer Sohn, 6507 Ingelheim | 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen |
US4084002A (en) * | 1973-02-28 | 1978-04-11 | Boehringer Ingelheim Gmbh | Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use |
US4161530A (en) * | 1975-01-06 | 1979-07-17 | Ciba-Geigy Corporation | Pharmaceutical combination preparations as hypnotics |
US4094991A (en) * | 1975-06-17 | 1978-06-13 | Nippon Shinyaku Co., Ltd. | Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives |
US4243681A (en) * | 1977-10-11 | 1981-01-06 | Mead Johnson & Company | Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof |
DE2839475A1 (de) * | 1978-09-11 | 1980-03-20 | Dolorgiet Arzneimittelfabrik | Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
EP0025331B1 (en) * | 1979-09-06 | 1983-03-02 | Beecham Group Plc | Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them |
JPS56142262A (en) | 1980-04-08 | 1981-11-06 | Nippon Shinyaku Co Ltd | Piperazine derivative |
US4593119A (en) * | 1980-11-28 | 1986-06-03 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
US4387103A (en) * | 1980-11-28 | 1983-06-07 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
US4405642A (en) * | 1980-11-28 | 1983-09-20 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
US4396629A (en) * | 1980-12-29 | 1983-08-02 | Sterling Drug Inc. | Compositions, processes and method |
DE3131527A1 (de) * | 1981-08-08 | 1983-02-24 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
AU575153B2 (en) * | 1984-04-09 | 1988-07-21 | Du Pont Merck Pharmaceutical Company, The | Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders |
US4652584A (en) * | 1984-07-13 | 1987-03-24 | Mcneilab, Inc. | Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension |
US4665094A (en) * | 1985-08-29 | 1987-05-12 | Merck & Co., Inc. | Oculoselective beta-blockers for treatment of elevated intraocular pressure |
US4945182A (en) * | 1985-12-24 | 1990-07-31 | Merck & Co., Inc. | Oculoselective beta-blockers |
ATE45724T1 (de) * | 1985-12-24 | 1989-09-15 | Merck & Co Inc | Okuloselektive betablocker. |
US5480908A (en) * | 1993-12-13 | 1996-01-02 | American Cyanamid Company | β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3459782A (en) * | 1963-08-26 | 1969-08-05 | Boehringer Sohn Ingelheim | 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes |
-
1967
- 1967-12-13 DE DE1643262A patent/DE1643262C3/de not_active Expired
-
1968
- 1968-04-03 BG BG012150A patent/BG17298A3/xx unknown
- 1968-04-30 BG BG012149A patent/BG17297A3/xx unknown
- 1968-12-07 ES ES361189A patent/ES361189A1/es not_active Expired
- 1968-12-10 CH CH1843568A patent/CH532015A/de not_active IP Right Cessation
- 1968-12-10 CH CH848471A patent/CH556816A/xx not_active IP Right Cessation
- 1968-12-11 NL NL686817768A patent/NL146709B/xx not_active IP Right Cessation
- 1968-12-11 FI FI683535A patent/FI49497C/fi active
- 1968-12-11 PH PH9832*UA patent/PH9266A/en unknown
- 1968-12-12 JP JP43091282A patent/JPS5220457B1/ja active Pending
- 1968-12-12 SE SE17070/68A patent/SE367396B/xx unknown
- 1968-12-12 YU YU2949/68A patent/YU33949B/xx unknown
- 1968-12-12 DK DK608568AA patent/DK131029B/da not_active IP Right Cessation
- 1968-12-12 CA CA037,721A patent/CA954528A/en not_active Expired
- 1968-12-13 HU HUBO1162A patent/HU162734B/hu unknown
- 1968-12-13 AT AT1216668A patent/AT292670B/de not_active IP Right Cessation
- 1968-12-13 BR BR204840/68A patent/BR6804840D0/pt unknown
- 1968-12-13 IE IE1519/68A patent/IE32758B1/xx unknown
- 1968-12-13 AT AT879570A patent/AT292674B/de active
- 1968-12-13 AT AT879770A patent/AT292676B/de active
- 1968-12-13 AT AT879970A patent/AT298459B/de not_active IP Right Cessation
- 1968-12-13 AT AT879870A patent/AT292677B/de active
- 1968-12-13 BG BG12146A patent/BG19135A3/xx unknown
- 1968-12-13 AT AT880270A patent/AT292680B/de active
- 1968-12-13 AT AT879470A patent/AT294799B/de not_active IP Right Cessation
- 1968-12-13 AT AT879370A patent/AT292673B/de active
- 1968-12-13 FR FR1596100D patent/FR1596100A/fr not_active Expired
- 1968-12-13 IL IL31266A patent/IL31266A/xx unknown
- 1968-12-13 AT AT880170A patent/AT292679B/de active
- 1968-12-13 AT AT880070A patent/AT292678B/de not_active IP Right Cessation
- 1968-12-13 BE BE725490D patent/BE725490A/xx not_active IP Right Cessation
- 1968-12-13 AT AT879670A patent/AT292675B/de not_active IP Right Cessation
- 1968-12-13 BG BG011231A patent/BG16329A3/bg unknown
- 1968-12-13 GB GB59518/68A patent/GB1260866A/en not_active Expired
- 1968-12-13 AT AT595771A patent/AT298463B/de not_active IP Right Cessation
-
1969
- 1969-03-13 FR FR183279A patent/FR8328M/fr not_active Expired
- 1969-04-30 BG BG012143A patent/BG16330A3/bg unknown
- 1969-04-30 BG BG012147A patent/BG16331A3/bg unknown
- 1969-04-30 BG BG012148A patent/BG16332A3/bg unknown
- 1969-04-30 BG BG012144A patent/BG16444A3/bg unknown
- 1969-04-30 BG BG012145A patent/BG16445A3/bg unknown
-
1970
- 1970-01-15 ES ES375453A patent/ES375453A1/es not_active Expired
- 1970-01-15 ES ES375451A patent/ES375451A1/es not_active Expired
- 1970-01-15 ES ES375447A patent/ES375447A1/es not_active Expired
- 1970-01-15 ES ES375445A patent/ES375445A1/es not_active Expired
- 1970-01-15 ES ES375449A patent/ES375449A1/es not_active Expired
- 1970-01-15 ES ES375444A patent/ES375444A1/es not_active Expired
- 1970-01-15 ES ES375452A patent/ES375452A1/es not_active Expired
- 1970-01-15 ES ES375448A patent/ES375448A1/es not_active Expired
- 1970-01-15 ES ES375446A patent/ES375446A1/es not_active Expired
- 1970-01-15 ES ES375450A patent/ES375450A1/es not_active Expired
- 1970-12-13 AT AT08803/70A patent/AT292681B/de active
-
1971
- 1971-12-02 US US204316A patent/US3872147A/en not_active Expired - Lifetime
-
1974
- 1974-09-03 YU YU2384/74A patent/YU33948B/xx unknown
- 1974-09-03 YU YU2375/74A patent/YU33946B/xx unknown
- 1974-09-03 YU YU2381/74A patent/YU33774B/xx unknown
- 1974-09-03 YU YU2377/74A patent/YU33947B/xx unknown
- 1974-09-03 YU YU2376/74A patent/YU33773B/xx unknown
- 1974-09-03 YU YU2380/74A patent/YU33854B/xx unknown
- 1974-09-03 YU YU2378/74A patent/YU33852B/xx unknown
- 1974-09-03 YU YU2379/74A patent/YU33853B/xx unknown
- 1974-09-03 YU YU2383/74A patent/YU33856B/xx unknown
- 1974-09-03 YU YU2382/74A patent/YU33855B/xx unknown
- 1974-09-03 YU YU2374/74A patent/YU33851B/xx unknown
-
1975
- 1975-02-14 NL NL7501792A patent/NL7501792A/xx unknown
- 1975-02-14 NL NL757501794A patent/NL151354B/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |