AT285836B - Verfahren zur Herstellung von neuen (Poly-β-äthoxyäthy)-3,20-dioxo-9α-fluor-11β,21-dihydroxy-16α- methyl-17α-R-pregna-1,4-dien-mischcarbonaten - Google Patents

Verfahren zur Herstellung von neuen (Poly-β-äthoxyäthy)-3,20-dioxo-9α-fluor-11β,21-dihydroxy-16α- methyl-17α-R-pregna-1,4-dien-mischcarbonaten

Info

Publication number
AT285836B
AT285836B AT389269A AT389269A AT285836B AT 285836 B AT285836 B AT 285836B AT 389269 A AT389269 A AT 389269A AT 389269 A AT389269 A AT 389269A AT 285836 B AT285836 B AT 285836B
Authority
AT
Austria
Prior art keywords
ethoxyethy
pregna
dioxo
dihydroxy
fluoro
Prior art date
Application number
AT389269A
Other languages
German (de)
English (en)
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of AT285836B publication Critical patent/AT285836B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16BDEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B39/00Locking of screws, bolts or nuts
    • F16B39/02Locking of screws, bolts or nuts in which the locking takes place after screwing down
    • F16B39/04Locking of screws, bolts or nuts in which the locking takes place after screwing down with a member penetrating the screw-threaded surface of at least one part, e.g. a pin, a wedge, cotter-pin, screw
    • F16B39/06Locking of screws, bolts or nuts in which the locking takes place after screwing down with a member penetrating the screw-threaded surface of at least one part, e.g. a pin, a wedge, cotter-pin, screw with a pin or staple parallel to the bolt axis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT389269A 1968-04-22 1969-04-22 Verfahren zur Herstellung von neuen (Poly-β-äthoxyäthy)-3,20-dioxo-9α-fluor-11β,21-dihydroxy-16α- methyl-17α-R-pregna-1,4-dien-mischcarbonaten AT285836B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR148895A FR7604M (enExample) 1968-04-22 1968-04-22

Publications (1)

Publication Number Publication Date
AT285836B true AT285836B (de) 1970-11-10

Family

ID=8649224

Family Applications (1)

Application Number Title Priority Date Filing Date
AT389269A AT285836B (de) 1968-04-22 1969-04-22 Verfahren zur Herstellung von neuen (Poly-β-äthoxyäthy)-3,20-dioxo-9α-fluor-11β,21-dihydroxy-16α- methyl-17α-R-pregna-1,4-dien-mischcarbonaten

Country Status (11)

Country Link
US (1) US3591612A (enExample)
AT (1) AT285836B (enExample)
BE (1) BE731782A (enExample)
CH (1) CH506508A (enExample)
DK (1) DK127976B (enExample)
ES (1) ES366287A1 (enExample)
FR (1) FR7604M (enExample)
GB (1) GB1208230A (enExample)
IL (1) IL31870A (enExample)
NL (1) NL6905568A (enExample)
SE (1) SE350255B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011003870A2 (en) * 2009-07-06 2011-01-13 Creabilis S.A. Mini-pegylated corticosteroids, compositions including same, and methods of making and using same
US11612567B2 (en) 2018-02-02 2023-03-28 Ripple Therapeutics Corporation Ocular inserts comprising a covalently linked steroid dimer
WO2020154815A1 (en) * 2019-02-01 2020-08-06 Ripple Therapeutics Corporation Crystalline forms of dexamethasone dimers and uses thereof
EP4146664A4 (en) 2020-05-01 2024-11-13 Ripple Therapeutics Corporation HETERODIMER COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES

Also Published As

Publication number Publication date
CH506508A (fr) 1971-04-30
IL31870A0 (en) 1969-05-28
DE1919811B2 (de) 1974-02-21
BE731782A (enExample) 1969-10-21
ES366287A1 (es) 1971-02-16
US3591612A (en) 1971-07-06
FR7604M (enExample) 1970-01-19
NL6905568A (enExample) 1969-10-24
IL31870A (en) 1972-10-29
DE1919811A1 (de) 1969-10-23
SE350255B (enExample) 1972-10-23
DK127976B (da) 1974-02-11
GB1208230A (en) 1970-10-07

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