DK127976B - Analogifremgangsmåde til fremstilling af 21-poly-β-ethoxyethyl-carbonater af 3,20-dioxo-9α-fluor-11β,17α,21-trihydroxy-16α-methylpregna-1,4-dien. - Google Patents

Analogifremgangsmåde til fremstilling af 21-poly-β-ethoxyethyl-carbonater af 3,20-dioxo-9α-fluor-11β,17α,21-trihydroxy-16α-methylpregna-1,4-dien.

Info

Publication number
DK127976B
DK127976B DK218669AA DK218669A DK127976B DK 127976 B DK127976 B DK 127976B DK 218669A A DK218669A A DK 218669AA DK 218669 A DK218669 A DK 218669A DK 127976 B DK127976 B DK 127976B
Authority
DK
Denmark
Prior art keywords
methylpregna
trihydroxy
dioxo
ethoxyethyl
diene
Prior art date
Application number
DK218669AA
Other languages
English (en)
Inventor
A Allais
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK127976B publication Critical patent/DK127976B/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B39/00—Locking of screws, bolts or nuts
    • F16B39/02—Locking of screws, bolts or nuts in which the locking takes place after screwing down
    • F16B39/04—Locking of screws, bolts or nuts in which the locking takes place after screwing down with a member penetrating the screw-threaded surface of at least one part, e.g. a pin, a wedge, cotter-pin, screw
    • F16B39/06—Locking of screws, bolts or nuts in which the locking takes place after screwing down with a member penetrating the screw-threaded surface of at least one part, e.g. a pin, a wedge, cotter-pin, screw with a pin or staple parallel to the bolt axis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK218669AA 1968-04-22 1969-04-22 Analogifremgangsmåde til fremstilling af 21-poly-β-ethoxyethyl-carbonater af 3,20-dioxo-9α-fluor-11β,17α,21-trihydroxy-16α-methylpregna-1,4-dien. DK127976B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR148895A FR7604M (da) 1968-04-22 1968-04-22

Publications (1)

Publication Number Publication Date
DK127976B true DK127976B (da) 1974-02-11

Family

ID=8649224

Family Applications (1)

Application Number Title Priority Date Filing Date
DK218669AA DK127976B (da) 1968-04-22 1969-04-22 Analogifremgangsmåde til fremstilling af 21-poly-β-ethoxyethyl-carbonater af 3,20-dioxo-9α-fluor-11β,17α,21-trihydroxy-16α-methylpregna-1,4-dien.

Country Status (11)

Country Link
US (1) US3591612A (da)
AT (1) AT285836B (da)
BE (1) BE731782A (da)
CH (1) CH506508A (da)
DK (1) DK127976B (da)
ES (1) ES366287A1 (da)
FR (1) FR7604M (da)
GB (1) GB1208230A (da)
IL (1) IL31870A (da)
NL (1) NL6905568A (da)
SE (1) SE350255B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011003870A2 (en) * 2009-07-06 2011-01-13 Creabilis S.A. Mini-pegylated corticosteroids, compositions including same, and methods of making and using same
CA3087898A1 (en) 2018-02-02 2019-08-08 Ripple Therapeutics Corporation Glass formulations comprising steroid dimers and uses thereof
US20220089635A1 (en) * 2019-02-01 2022-03-24 Ripple Therapeutics Corporation Crystalline forms of dexamethasone dimers and uses thereof
CA3176134A1 (en) 2020-05-01 2021-11-04 Ripple Therapeutics Corporation Heterodimer compositions and methods for the treatment of ocular disorders

Also Published As

Publication number Publication date
GB1208230A (en) 1970-10-07
AT285836B (de) 1970-11-10
IL31870A0 (en) 1969-05-28
IL31870A (en) 1972-10-29
DE1919811A1 (de) 1969-10-23
NL6905568A (da) 1969-10-24
ES366287A1 (es) 1971-02-16
SE350255B (da) 1972-10-23
FR7604M (da) 1970-01-19
CH506508A (fr) 1971-04-30
US3591612A (en) 1971-07-06
DE1919811B2 (de) 1974-02-21
BE731782A (da) 1969-10-21

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