AT223002B - Feed - Google Patents
FeedInfo
- Publication number
- AT223002B AT223002B AT198261A AT198261A AT223002B AT 223002 B AT223002 B AT 223002B AT 198261 A AT198261 A AT 198261A AT 198261 A AT198261 A AT 198261A AT 223002 B AT223002 B AT 223002B
- Authority
- AT
- Austria
- Prior art keywords
- sep
- feed
- vitamin
- ubiquinones
- growth
- Prior art date
Links
- 235000017471 coenzyme Q10 Nutrition 0.000 claims description 9
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 claims 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 claims 1
- NPCOQXAVBJJZBQ-UHFFFAOYSA-N reduced coenzyme Q9 Natural products COC1=C(O)C(C)=C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)C(O)=C1OC NPCOQXAVBJJZBQ-UHFFFAOYSA-N 0.000 claims 1
- 229940035936 ubiquinone Drugs 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 description 17
- 229930003231 vitamin Natural products 0.000 description 17
- 235000013343 vitamin Nutrition 0.000 description 17
- 239000011782 vitamin Substances 0.000 description 17
- 150000003722 vitamin derivatives Chemical class 0.000 description 15
- 239000000203 mixture Substances 0.000 description 10
- 150000003669 ubiquinones Chemical class 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 6
- 244000144977 poultry Species 0.000 description 6
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 4
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 4
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 4
- 229930006000 Sucrose Natural products 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 description 3
- 229960004793 sucrose Drugs 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 description 2
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 229960004050 aminobenzoic acid Drugs 0.000 description 2
- 229960002685 biotin Drugs 0.000 description 2
- 235000020958 biotin Nutrition 0.000 description 2
- 239000011616 biotin Substances 0.000 description 2
- 239000011203 carbon fibre reinforced carbon Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229960000304 folic acid Drugs 0.000 description 2
- 235000019152 folic acid Nutrition 0.000 description 2
- 239000011724 folic acid Substances 0.000 description 2
- 239000004459 forage Substances 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 235000005152 nicotinamide Nutrition 0.000 description 2
- 239000011570 nicotinamide Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 description 2
- 229960004172 pyridoxine hydrochloride Drugs 0.000 description 2
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 description 2
- 239000011764 pyridoxine hydrochloride Substances 0.000 description 2
- 229960002477 riboflavin Drugs 0.000 description 2
- 235000002639 sodium chloride Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 2
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 239000004255 Butylated hydroxyanisole Substances 0.000 description 1
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
- 235000019743 Choline chloride Nutrition 0.000 description 1
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 229910016876 Fe(NH4)2(SO4)2 Inorganic materials 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 229920002494 Zein Polymers 0.000 description 1
- ZLXPLDLEBORRPT-UHFFFAOYSA-M [NH4+].[Fe+].[O-]S([O-])(=O)=O Chemical compound [NH4+].[Fe+].[O-]S([O-])(=O)=O ZLXPLDLEBORRPT-UHFFFAOYSA-M 0.000 description 1
- 239000002156 adsorbate Substances 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 235000019282 butylated hydroxyanisole Nutrition 0.000 description 1
- 229940043253 butylated hydroxyanisole Drugs 0.000 description 1
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 description 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 1
- 229940095259 butylated hydroxytoluene Drugs 0.000 description 1
- 229960002079 calcium pantothenate Drugs 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 description 1
- 229960003178 choline chloride Drugs 0.000 description 1
- 229940044175 cobalt sulfate Drugs 0.000 description 1
- 229910000361 cobalt sulfate Inorganic materials 0.000 description 1
- KTVIXTQDYHMGHF-UHFFFAOYSA-L cobalt(2+) sulfate Chemical compound [Co+2].[O-]S([O-])(=O)=O KTVIXTQDYHMGHF-UHFFFAOYSA-L 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- -1 diphosphoric acid ester Chemical class 0.000 description 1
- 235000013345 egg yolk Nutrition 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 229940099596 manganese sulfate Drugs 0.000 description 1
- 239000011702 manganese sulphate Substances 0.000 description 1
- 235000007079 manganese sulphate Nutrition 0.000 description 1
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 150000004053 quinones Chemical class 0.000 description 1
- 239000011833 salt mixture Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 229960000344 thiamine hydrochloride Drugs 0.000 description 1
- 235000019190 thiamine hydrochloride Nutrition 0.000 description 1
- 239000011747 thiamine hydrochloride Substances 0.000 description 1
- 229940034208 thyroxine Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
- 235000012711 vitamin K3 Nutrition 0.000 description 1
- 239000011652 vitamin K3 Substances 0.000 description 1
- 229940041603 vitamin k 3 Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 239000005019 zein Substances 0.000 description 1
- 229940093612 zein Drugs 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
- 235000005074 zinc chloride Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/30—Other Organic compounds
- A23V2250/314—Ubiquinone, coenzyme Qn
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Birds (AREA)
- Fodder In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
<Desc/Clms Page number 1>
Futtermittel
Die vorliegende Erfindung betrifft ein Futtermittel mit wachstumsfördernder Wirkung auf Nutztiere, insbesondere auf Geflügel, sowie dessen Herstellungsverfahren und dessen Anwendung.
Intensive Untersuchungen in den letzten Jahren haben Klarheit darüber gebracht, welche Bedingungen ein Futtermittel in ernährungstechnischer Hinsicht erfüllen muss, wobei die Bestimmung des richtigen Verhältnisses von Eiweissen, Kohlehydraten, Mineralsalzen und Vitaminen im Vordergrund stand. Dar- über hinaus konnte man aber auch feststellen, dass verschiedene Wachstumsfaktoren eine bedeutende Rolle spielen. Diese Wachstumsfaktoren sind jedoch derzeit noch zum Uberwiegenden Teil unbekannt. Bei Geflügel handelt es sich dabei um Faktoren, die z. B. im Fischpresswasser, in der Molke, in Gärungsrlick- ständen, in Hefe, Leber und Eigelb vorkommen.
Es ist nun gefunden worden, dass die in den letzten Jahren aus natürlichen Quellen isolierten und auch synthetisch hergestellten Ubichinone der allgemeinen Formel
EMI1.1
worin n eine ganze Zahl von 1 bis 9 bezeichnet und Y und Z je Wasserstoff oder eine zusätzliche Kohlenstoff-Kohlenstoff-Bindung bedeuten, bei Nutztieren, insbesondere bei Geflügel, eine Wachstumssteigerung über die normalerweise zu erwartende Wachstumsrate hinaus bewirken, wenn derartige Ubichinone zusammen mit einem alle lebensnotwendigen Elemente enthaltenden Futtermittel verfüttert werden. Verbindungen der vorstehenden allgemeinen Formel können z. B. entsprechend den Angaben in Helv. Chim.
Acta 41 [1958], S. 2343, 2357, und 42 [1959], S. 2616, gewonnen bzw. synthetisiert werden.
Die Erfindung betrifft demnach ein Futtermittel mit wachstumsfördernder Wirkung auf Nutztiere, insbesondere auf Geflügel, das durch einen Zusatz von Ubichinonen der Formel I gekennzeichnet ist.
Bevorzugt ist eine Verbindung der allgemeinen Formel I, worin n 3 bedeutet und der Klammerausdruck gesättigt ist. Das erfindungsgemässe Futtermittel besteht zweckmässig aus einem Gemisch eines Ublichen Mastfutters (Alleinfutter oder Mischfutter, das z. B. mit Zusatz von Getreide verarbeitet wird) mit den erwähnten Ubichinonen, deren Konzentration mit Vorteil 1 - 100 mg, insbesondere 1 - 20 mg je kg Futter beträgt. beträgt.
Das zur Herbeiführung der Wachstumsförderung geeignete Futtermittel kann erfindungsgemäss durch Beimischung von Ubichinonen der Formel I zu einem Grundfutter hergestellt werden. Die Ubichinone können in beliebiger Form zugesetzt werden, z. B. als Trockensubstanz in reiner Form, als Trockenpulver in einer Schutzmasse (z. B. Gelatine) eingebettet, als Adsorbat (z. B. an Hafermehl). Falls die erfin- dungsgemäss vorgeschlagenen Ubichinone dem Grundfutter nicht in reiner Form, sondern in Form von Vorgemischen zugesetzt werden, können diese Vorgemische Verdünnungsmittel enthalten, welche selbst
<Desc/Clms Page number 2>
Nährwirkung und/oder wachstumsfördernde Eigenschaften besitzen. Ausserdem können diese Vorgemische
Stabilisatoren, wie z.
B. butyliertes Hydroxytoluol oder butyliertes Hydroxyanisol, zum Schutze der ver- wendeten Wirkstoffe enthalten.
Gemäss einer weiteren Ausführungsform kann der Zusatz der erfindungsgemäss vorgeschlagenen Ubii chinone auch durch Versprühen einer öligen Lösung der Wirkstoffe auf ein Grundfuttermittel erfolgen.
Ein gemäss den obigen Angaben erhaltenes Futtermittel kann wie Üblich verfüttert werden. Die Ver- fütterung erfolgt bei Geflügel zweckmässig beginnend mit dem Schlupf bis zur Schlachtreife und insbe- sondere in den ersten fünf Lebenswochen der Tiere.
Beispiel l : Als Grundfutter wurde ein Gemisch der folgenden Zusammensetzung verwendet :
EMI2.1
<tb>
<tb> Sojaextraktionsschrot <SEP> 49, <SEP> 0%
<tb> Rohrzucker <SEP> 42, <SEP> 02%
<tb> Zein <SEP> 0, <SEP> 40/0 <SEP>
<tb> DL- <SEP> Methionin <SEP> 0, <SEP> 20/0 <SEP>
<tb> Cholinchlorid. <SEP> 0. <SEP> 076% <SEP>
<tb> i <SEP> l%iges <SEP> Jod-Casein <SEP> (bez. <SEP> auf <SEP> Thyroxin) <SEP> 0, <SEP> 03%
<tb> Salzmischung'5, <SEP> 274% <SEP>
<tb> Vitaminmischung <SEP> 3, <SEP> 0%
<tb>
EMI2.2
EMI2.3
<tb>
<tb> DieDicalciumphosphat <SEP> 63, <SEP> 85%
<tb> Schlämmkreide <SEP> 23, <SEP> 15%
<tb> Kochsalz <SEP> jodiert <SEP> 8, <SEP> 65%
<tb> Eisenammoniumsulfat <SEP> krist.
<tb>
[Fe(NH4)2(SO4)2. <SEP> 6 <SEP> H2 <SEP> O] <SEP> 3,63%
<tb> Mangansulfat <SEP> 0, <SEP> 60%
<tb> Kaliumjodid <SEP> 0, <SEP> 067%
<tb> Zinkchlorid <SEP> 0, <SEP> 034%
<tb> Kobaltsulfat <SEP> (CoS04. <SEP> 7 <SEP> 1\0) <SEP> 0. <SEP> 00350/0
<tb> Borsäure.', <SEP> 0, <SEP> 0155% <SEP>
<tb>
Die vorstehend angeführte Vitaminmischung hatte folgende Zusammensetzung :
EMI2.4
<tb>
<tb> Nicotinsäureamid <SEP> 4500 <SEP> mg
<tb> D <SEP> (+)-Calciumpantothenat <SEP> 1800 <SEP> mg
<tb> Vitamin <SEP> 8"-Mannit <SEP> 13905 <SEP> mg
<tb> (405 <SEP> mg <SEP> eines <SEP> 0, <SEP> 05%igen <SEP> Vitamin <SEP> BKonzentrates <SEP> werden <SEP> mit <SEP> 13500 <SEP> mg
<tb> D-Mannit <SEP> gemischt)
<tb> Pyridoxin-hydrochlorid <SEP> 675 <SEP> mg
<tb> Lactoflavin <SEP> 675 <SEP> mg
<tb> p-Aminobenzoesäure <SEP> 315 <SEP> mg
<tb> Menadion <SEP> 135 <SEP> mg
<tb> Folsäure <SEP> 112, <SEP> 5 <SEP> mg
<tb> Biotin <SEP> 13, <SEP> 5 <SEP> mg
<tb> Gelatine-geschützte <SEP> Vitamin <SEP> A <SEP> + <SEP> D3 <SEP> 40500 <SEP> mg
<tb> (50 <SEP> 000 <SEP> I. <SEP> E. <SEP> Vitamin <SEP> A/g <SEP> und
<tb> 12 <SEP> 500 <SEP> I. <SEP> E. <SEP> Vitamin <SEP> D3/g)
<tb> Gelatine-geschutztes <SEP> Vitamin <SEP> E <SEP> 13500 <SEP> mg
<tb> (1001.
<SEP> E./g) <SEP>
<tb>
Vorstehende Vitaminmischung wird mit Rohrzucker gemischt, so dass das Endgewicht 4,5 kg beträgt.
Diesem Grundfutter wurde in Form eines Gelatine-geschützten Präparates 2, 3-Dimethoxy-5-methyl- - 6-[3', 1, 11'. 15', 19', 23', 21, 31', 35', 39' -decamethyl-tetracontadecaen- {2', 6', 10', 14'. 18', 22', 26', 30', 34', 38') - - yl]-benzochinon- (l, 4) im Ausmass von 8 mg Reinsubstanz je kg Futter beigemischt.
Das vorstehend beschriebene Futter wurde einer Gruppe von männlichen Kücken aus einer Kreuzung
EMI2.5
<Desc/Clms Page number 3>
Beispiel 2 : Man verwendet ein Grundfutter der in Beispiel 1 beschriebenen Zusammenwrxung, ändert jedoch die Vitaminmischung wie folgt ab :
EMI3.1
<tb>
<tb> Nicotinsäureamid <SEP> 3600 <SEP> mg
<tb> D(+)-Calciumpantotheriat <SEP> 1440 <SEP> mg
<tb> Vitamin <SEP> B19-mannit <SEP> (0, <SEP> 10/0ig) <SEP> 1620 <SEP> mg
<tb> Pyridoxin-hydrochlorid <SEP> 540 <SEP> mg
<tb> Lactoflavin <SEP> 540 <SEP> mg
<tb> Thiamin-hydrochlorid <SEP> 540 <SEP> mg
<tb> p-Aminobenzoesäure <SEP> 252 <SEP> mg
<tb> Natriumsalz <SEP> des <SEP> Diphosphorsäurcesters <SEP> von
<tb> 2-Methyl-l, <SEP> 4-naphthohydrochinon <SEP> 216 <SEP> mg
<tb> Folsäure <SEP> nu <SEP> mg
<tb> Biotin <SEP> 1t), <SEP> 8 <SEP> mg <SEP>
<tb> Gelatine-geschlitzte <SEP> Vitamine <SEP> A <SEP> + <SEP> D5
<tb> (50 <SEP> 000 <SEP> t. <SEP> E.
<SEP> Vitamin <SEP> A/g <SEP> und
<tb> 1250U <SEP> I. <SEP> E. <SEP> Vitamin <SEP> D3/g) <SEP> 32400 <SEP> mg
<tb> Gelatine-geschütztes <SEP> Vitamin <SEP> E <SEP> (20 <SEP> I. <SEP> E./g) <SEP> 4320 <SEP> mg <SEP>
<tb>
Vorstehende Vitaminmischung wird mit Rohrzucker gemischt, so dass das Endgewicht 3,6 kg beträgt.
Diesem Grundfutter wurde in Form eines Gelatine-geschützten Präparates e, 3-Dimethoxy-6-methyl-
EMI3.2
hornrasse vom zweiten Lebenstag an verfüttert. Die Tiere wurden jede Woche gewogen. Nach 6 Wochen zeigte sich, dass die Gewichtszunahme im Durchschnitt um etwa 9% höher lag als hei entsprechenden Kontrolltieren. welche wirkstofffreies Futter erhielten.
PATENTANSPRÜCHE :
1. Futtermittel mit wachstumsfördernder Wirkung auf Nutztiere, insbesondere auf Geflügel, gekennzeichnet durch einen Zusatz von einem oder mehreren Ubichinonen der allgemeinen Formel
EMI3.3
worin n eine ganze Zahl von 1 bis 9 bezeichnet und Y und Z je Wasserstoff oder zusammen eine zusätzliche Kohlenstoff-Kohlenstoff-Bindung bedeuten.
<Desc / Clms Page number 1>
Feed
The present invention relates to a feed with a growth-promoting effect on farm animals, in particular on poultry, as well as its production method and its application.
Intensive investigations in recent years have clarified which conditions a feed must meet in terms of nutritional technology, with the focus on determining the correct ratio of proteins, carbohydrates, mineral salts and vitamins. In addition, it was also found that various growth factors play an important role. However, these growth factors are currently largely unknown. In poultry, these are factors that affect e.g. B. in fish press water, in whey, in fermentation lick stalls, in yeast, liver and egg yolk.
It has now been found that the ubiquinones of the general formula isolated from natural sources in recent years and also synthetically produced
EMI1.1
where n denotes an integer from 1 to 9 and Y and Z each denote hydrogen or an additional carbon-carbon bond, in livestock, especially in poultry, cause an increase in growth above the normally expected growth rate when such ubiquinones together with a feed containing all essential elements. Compounds of the above general formula can e.g. B. according to the information in Helv. Chim.
Acta 41 [1958], p. 2343, 2357, and 42 [1959], p. 2616, obtained or synthesized.
The invention accordingly relates to a feed with a growth-promoting effect on farm animals, in particular on poultry, which is characterized by the addition of ubiquinones of the formula I.
A compound of the general formula I in which n is 3 and the expression in brackets is saturated is preferred. The feed according to the invention expediently consists of a mixture of a customary fattening feed (complete feed or mixed feed, which is processed e.g. with the addition of grain) with the ubiquinones mentioned, whose concentration is advantageously 1-100 mg, in particular 1-20 mg per kg feed amounts. amounts.
The feed which is suitable for promoting growth can be produced according to the invention by adding ubiquinones of the formula I to a basic feed. The ubiquinones can be added in any form, e.g. B. as a dry substance in pure form, as a dry powder embedded in a protective mass (e.g. gelatin), as an adsorbate (e.g. on oatmeal). If the ubiquinones proposed according to the invention are added to the basic feed not in pure form but in the form of premixes, these premixes can contain diluents which themselves
<Desc / Clms Page number 2>
Have nutritional and / or growth-promoting properties. In addition, these premixes
Stabilizers such as
B. butylated hydroxytoluene or butylated hydroxyanisole to protect the active ingredients used.
According to a further embodiment, the ubii quinones proposed according to the invention can also be added by spraying an oily solution of the active ingredients onto a basic feed.
A feed obtained according to the above information can be fed as usual. In the case of poultry, it is advisable to feed them starting with hatching until they are ready for slaughter and especially in the first five weeks of the animals' life.
Example 1: A mixture of the following composition was used as basic forage:
EMI2.1
<tb>
<tb> Soy extraction meal <SEP> 49, <SEP> 0%
<tb> cane sugar <SEP> 42, <SEP> 02%
<tb> Zein <SEP> 0, <SEP> 40/0 <SEP>
<tb> DL- <SEP> methionine <SEP> 0, <SEP> 20/0 <SEP>
<tb> choline chloride. <SEP> 0. <SEP> 076% <SEP>
<tb> i <SEP> 1% <SEP> iodine-casein <SEP> (referring to <SEP> to <SEP> thyroxine) <SEP> 0, <SEP> 03%
<tb> Salt mixture'5, <SEP> 274% <SEP>
<tb> Vitamin mixture <SEP> 3, <SEP> 0%
<tb>
EMI2.2
EMI2.3
<tb>
<tb> DieDicalciumphosphat <SEP> 63, <SEP> 85%
<tb> whitening chalk <SEP> 23, <SEP> 15%
<tb> table salt <SEP> iodized <SEP> 8, <SEP> 65%
<tb> iron ammonium sulfate <SEP> crystall.
<tb>
[Fe (NH4) 2 (SO4) 2. <SEP> 6 <SEP> H2 <SEP> O] <SEP> 3.63%
<tb> Manganese sulfate <SEP> 0, <SEP> 60%
<tb> Potassium iodide <SEP> 0, <SEP> 067%
<tb> zinc chloride <SEP> 0, <SEP> 034%
<tb> cobalt sulfate <SEP> (CoS04. <SEP> 7 <SEP> 1 \ 0) <SEP> 0. <SEP> 00350/0
<tb> Boric acid. ', <SEP> 0, <SEP> 0155% <SEP>
<tb>
The vitamin mixture listed above had the following composition:
EMI2.4
<tb>
<tb> Nicotinic acid amide <SEP> 4500 <SEP> mg
<tb> D <SEP> (+) - calcium pantothenate <SEP> 1800 <SEP> mg
<tb> Vitamin <SEP> 8 "-Mannitol <SEP> 13905 <SEP> mg
<tb> (405 <SEP> mg <SEP> of a <SEP> 0, <SEP> 05% <SEP> vitamin <SEP> B concentrate <SEP> become <SEP> with <SEP> 13500 <SEP> mg
<tb> D-mannitol <SEP> mixed)
<tb> pyridoxine hydrochloride <SEP> 675 <SEP> mg
<tb> Lactoflavin <SEP> 675 <SEP> mg
<tb> p-aminobenzoic acid <SEP> 315 <SEP> mg
<tb> Menadione <SEP> 135 <SEP> mg
<tb> Folic acid <SEP> 112, <SEP> 5 <SEP> mg
<tb> Biotin <SEP> 13, <SEP> 5 <SEP> mg
<tb> Gelatin-protected <SEP> vitamin <SEP> A <SEP> + <SEP> D3 <SEP> 40500 <SEP> mg
<tb> (50 <SEP> 000 <SEP> I. <SEP> E. <SEP> Vitamin <SEP> A / g <SEP> and
<tb> 12 <SEP> 500 <SEP> I. <SEP> E. <SEP> Vitamin <SEP> D3 / g)
<tb> Gelatin-protected <SEP> vitamin <SEP> E <SEP> 13500 <SEP> mg
<tb> (1001.
<SEP> E./g) <SEP>
<tb>
The above vitamin mixture is mixed with cane sugar so that the final weight is 4.5 kg.
This basic feed was in the form of a gelatin-protected preparation 2, 3-dimethoxy-5-methyl- - 6- [3 ', 1, 11'. 15 ', 19', 23 ', 21, 31', 35 ', 39' -decamethyl-tetracontadecaen- {2 ', 6', 10 ', 14'. 18 ', 22', 26 ', 30', 34 ', 38') - - yl] -benzoquinone- (1,4) added to the extent of 8 mg pure substance per kg feed.
The diet described above was given to a group of male chicks from a cross
EMI2.5
<Desc / Clms Page number 3>
Example 2: A basic forage of the composition described in Example 1 is used, but the vitamin mixture is changed as follows:
EMI3.1
<tb>
<tb> Nicotinic acid amide <SEP> 3600 <SEP> mg
<tb> D (+) - Calcium pantotherate <SEP> 1440 <SEP> mg
<tb> Vitamin <SEP> B19-mannit <SEP> (0, <SEP> 10 / 0ig) <SEP> 1620 <SEP> mg
<tb> pyridoxine hydrochloride <SEP> 540 <SEP> mg
<tb> Lactoflavin <SEP> 540 <SEP> mg
<tb> Thiamine hydrochloride <SEP> 540 <SEP> mg
<tb> p-aminobenzoic acid <SEP> 252 <SEP> mg
<tb> Sodium salt <SEP> of the <SEP> diphosphoric acid ester <SEP> of
<tb> 2-methyl-1, <SEP> 4-naphthohydroquinone <SEP> 216 <SEP> mg
<tb> folic acid <SEP> nu <SEP> mg
<tb> Biotin <SEP> 1t), <SEP> 8 <SEP> mg <SEP>
<tb> Gelatin-slotted <SEP> vitamins <SEP> A <SEP> + <SEP> D5
<tb> (50 <SEP> 000 <SEP> t. <SEP> E.
<SEP> Vitamin <SEP> A / g <SEP> and
<tb> 1250U <SEP> I. <SEP> E. <SEP> Vitamin <SEP> D3 / g) <SEP> 32400 <SEP> mg
<tb> Gelatin-protected <SEP> vitamin <SEP> E <SEP> (20 <SEP> I. <SEP> E./g) <SEP> 4320 <SEP> mg <SEP>
<tb>
The above vitamin mixture is mixed with cane sugar so that the final weight is 3.6 kg.
This basic feed was in the form of a gelatin-protected preparation e, 3-dimethoxy-6-methyl-
EMI3.2
horn breed fed from the second day of life. The animals were weighed every week. After 6 weeks it was found that the weight gain was on average about 9% higher than in corresponding control animals. who received inactive feed.
PATENT CLAIMS:
1. Feed with a growth-promoting effect on farm animals, in particular on poultry, characterized by the addition of one or more ubiquinones of the general formula
EMI3.3
where n denotes an integer from 1 to 9 and Y and Z each denote hydrogen or together denote an additional carbon-carbon bond.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH223002X | 1960-03-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT223002B true AT223002B (en) | 1962-08-27 |
Family
ID=4452835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT198261A AT223002B (en) | 1960-03-22 | 1961-03-10 | Feed |
Country Status (1)
| Country | Link |
|---|---|
| AT (1) | AT223002B (en) |
-
1961
- 1961-03-10 AT AT198261A patent/AT223002B/en active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69414180T2 (en) | Composition that improves the digestibility of ruminant feed | |
| DE1966491B2 (en) | ||
| EP1176875A1 (en) | Use of creatine as a fat substitute | |
| DE3242501C1 (en) | Use of aqueous L-lysine solutions to supplement feed with L-lysine | |
| DE2848184A1 (en) | ADDITION TO A SUPPLEMENTARY FEED FOR Cattle | |
| DE3105009C2 (en) | Use of aqueous sodium or potassium methioninate solutions for supplementation of compound feeds with methionine and method for supplementation | |
| AT223002B (en) | Feed | |
| Peo Jr et al. | Grain sorghum for growing-finishing swine | |
| DE2618269C2 (en) | ||
| DE1954226B2 (en) | Use of a quinoxaline derivative as part of a direct feed for pets | |
| DE3705186A1 (en) | VETERINA MEDICAL PREPARATIONS | |
| DE2018115A1 (en) | Feed | |
| EP0073390B1 (en) | Combination of active substances from kitasamycine and quinoxaline-di-n oxides | |
| AT372854B (en) | METHOD FOR PREVENTING THE DEVELOPMENT OF ENGRAVING HEALTH INTERFERENCE IN RETURNS AND FOR PREVENTING DEER BITE | |
| AT209163B (en) | Complementary feed | |
| AT211644B (en) | Preparations for promoting the growth of animals | |
| DE1692477C (en) | Growth promoting feed | |
| AT327664B (en) | COMPOSITION AND METHOD OF PREVENTING THE GROWTH OF PATHOGENIC SUBSTANCES | |
| AT346163B (en) | FEED TO PROMOTE THE GROWTH OF DOMESTIC AND FARM ANIMALS | |
| DE1692405C (en) | Process for the production of growth-promoting feed and drink mixes | |
| DE2233117B2 (en) | Animal feed containing a benzodiazepine derivative | |
| DE102005063251B4 (en) | Process for producing an organo-mineral fertilizer | |
| DE1492910C3 (en) | ||
| DE1808711C (en) | Feed for ruminants | |
| DE1692477B1 (en) | Growth promoting feed |