AR248025A1 - Procedimiento de obtencion de pirrolo/2, 3-b/indol-cetonas y compuestos analogos, utiles como medicamentos. - Google Patents

Procedimiento de obtencion de pirrolo/2, 3-b/indol-cetonas y compuestos analogos, utiles como medicamentos.

Info

Publication number
AR248025A1
AR248025A1 AR91319659A AR31965991A AR248025A1 AR 248025 A1 AR248025 A1 AR 248025A1 AR 91319659 A AR91319659 A AR 91319659A AR 31965991 A AR31965991 A AR 31965991A AR 248025 A1 AR248025 A1 AR 248025A1
Authority
AR
Argentina
Prior art keywords
alkyl
aryl
preparation
carbonyl
pyrrolo
Prior art date
Application number
AR91319659A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of AR248025A1 publication Critical patent/AR248025A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)

Abstract

PREPARACION DE UN COMPUESTO DE FORMULA I, EN QUE R1 ES ALQUILO, ARILO O ARIL-ALQUILO; R2 ES H, HALOGENO O ALQUILO; R3 ES H O ALQUILO; R4 ES ALQUILO O ARIL-ALQUILO; R5 ES H, ALQUILO, ALQUENILO, ALQUINILO, ARIL-ALQUILO, FORMILO, ALQUIL, CARBONILO, ARIL-ALQUIL, CARBONILO O ALCOXI, CARBONILO; Y ES H, HALOGENO, ALQUILO, O ALCOXI; O SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES, QUE COMPRENDE HACER REACCIONAR UN COMPUESTO DE FORMULA III, CON METOXIDO DE TRIBUTILESTANO Y ACETATO DE ISOPROPENILO EN PRESENCIA DE UNA CANTIDAD CATALITICA DE ACETATO DE PALADIO Y TRI-O-TOLILFOSFINA.
AR91319659A 1990-05-11 1991-05-09 Procedimiento de obtencion de pirrolo/2, 3-b/indol-cetonas y compuestos analogos, utiles como medicamentos. AR248025A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52195390A 1990-05-11 1990-05-11

Publications (1)

Publication Number Publication Date
AR248025A1 true AR248025A1 (es) 1995-05-31

Family

ID=24078810

Family Applications (1)

Application Number Title Priority Date Filing Date
AR91319659A AR248025A1 (es) 1990-05-11 1991-05-09 Procedimiento de obtencion de pirrolo/2, 3-b/indol-cetonas y compuestos analogos, utiles como medicamentos.

Country Status (18)

Country Link
EP (1) EP0456196A1 (es)
JP (1) JP3061442B2 (es)
KR (1) KR100197328B1 (es)
AR (1) AR248025A1 (es)
AU (1) AU634654B2 (es)
CA (1) CA2042327C (es)
CZ (1) CZ286092B6 (es)
FI (1) FI94760C (es)
HU (1) HUT61309A (es)
IE (1) IE911606A1 (es)
IL (1) IL98094A (es)
MX (1) MX25721A (es)
NO (1) NO178890C (es)
NZ (1) NZ238094A (es)
PL (1) PL290200A1 (es)
PT (1) PT97622A (es)
RU (1) RU2015979C1 (es)
ZA (1) ZA913534B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983616A (en) * 1990-02-01 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
FR2772516B1 (fr) 1997-12-12 2003-07-04 Ela Medical Sa Circuit electronique, notamment pour un dispositif medical implantable actif tel qu'un stimulateur ou defibrillateur cardiaque, et son procede de realisation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
US5077289A (en) * 1989-11-30 1991-12-31 Hoechst Roussel Pharmaceuticals Inc. Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine
US4983616A (en) * 1990-02-01 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
AU634380B2 (en) * 1990-05-17 1993-02-18 Hoechst-Roussel Pharmaceuticals Incorporated Alpha-oxopyrrolo(2,3-b)indole acetic acids, esters, amides and related analogs, a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
FI912247A0 (fi) 1991-05-09
FI94760B (fi) 1995-07-14
EP0456196A1 (en) 1991-11-13
ZA913534B (en) 1992-03-25
HU911574D0 (en) 1991-11-28
IE911606A1 (en) 1991-11-20
CS138391A3 (en) 1991-12-17
CA2042327A1 (en) 1991-11-12
KR100197328B1 (ko) 1999-06-15
PL290200A1 (en) 1992-07-27
KR910020013A (ko) 1991-12-19
IL98094A (en) 1996-01-31
AU7622891A (en) 1991-11-14
MX25721A (es) 1993-10-01
CZ286092B6 (cs) 2000-01-12
IL98094A0 (en) 1992-06-21
NO911810D0 (no) 1991-05-10
NZ238094A (en) 1994-05-26
HUT61309A (en) 1992-12-28
AU634654B2 (en) 1993-02-25
JPH04226987A (ja) 1992-08-17
JP3061442B2 (ja) 2000-07-10
FI94760C (fi) 1995-10-25
PT97622A (pt) 1992-02-28
CA2042327C (en) 2001-12-04
NO178890C (no) 1996-06-26
NO178890B (no) 1996-03-18
NO911810L (no) 1991-11-12
FI912247A (fi) 1991-11-12
RU2015979C1 (ru) 1994-07-15

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