AR230272A1 - Un nuevo procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi-4-metoxietoxi-bencil)-pirimidina - Google Patents

Un nuevo procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi-4-metoxietoxi-bencil)-pirimidina

Info

Publication number
AR230272A1
AR230272A1 AR290240A AR29024082A AR230272A1 AR 230272 A1 AR230272 A1 AR 230272A1 AR 290240 A AR290240 A AR 290240A AR 29024082 A AR29024082 A AR 29024082A AR 230272 A1 AR230272 A1 AR 230272A1
Authority
AR
Argentina
Prior art keywords
metoxietoxi
dimetoxi
bencil
pirimidine
diamino
Prior art date
Application number
AR290240A
Other languages
English (en)
Spanish (es)
Original Assignee
Proter Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11207307&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR230272(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Proter Spa filed Critical Proter Spa
Application granted granted Critical
Publication of AR230272A1 publication Critical patent/AR230272A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AR290240A 1981-08-11 1982-08-06 Un nuevo procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi-4-metoxietoxi-bencil)-pirimidina AR230272A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23462/81A IT1138146B (it) 1981-08-11 1981-08-11 Processo per la produzione della 2,4-diammino-(3,5-dimetossi-4-metos sietossi-benzil)-pirimidina

Publications (1)

Publication Number Publication Date
AR230272A1 true AR230272A1 (es) 1984-03-01

Family

ID=11207307

Family Applications (1)

Application Number Title Priority Date Filing Date
AR290240A AR230272A1 (es) 1981-08-11 1982-08-06 Un nuevo procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi-4-metoxietoxi-bencil)-pirimidina

Country Status (10)

Country Link
US (1) US4485248A (de)
EP (1) EP0071741B1 (de)
AR (1) AR230272A1 (de)
AT (1) ATE16800T1 (de)
CA (1) CA1182819A (de)
DE (1) DE3267778D1 (de)
ES (1) ES514224A0 (de)
IT (1) IT1138146B (de)
MX (1) MX156026A (de)
YU (1) YU161382A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1725540E (pt) * 2004-03-05 2012-11-29 Hoffmann La Roche Diaminopirimidinas como antagonistas de p2x3 e p2x2/3
JP4850913B2 (ja) * 2005-09-01 2012-01-11 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ３及びｐ２ｘ２／３調節因子としてのジアミノピリジン
WO2007025899A1 (en) * 2005-09-01 2007-03-08 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators
MX2008002731A (es) * 2005-09-01 2008-03-26 Hoffmann La Roche Diaminopirimidinas como moduladores de p2x3 y p3x2/3.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
DE2165362A1 (de) * 1970-12-29 1972-07-27 Nisshin Flour Milling Co. Ltd., Tokio .-Verfahren zur Herstellung von Pyrimidinderivaten
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
YU34880B (en) * 1972-05-08 1980-04-30 Pliva Pharm & Chem Works Process for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine
US4143227A (en) * 1973-02-26 1979-03-06 Hoffmann-La Roche Inc. Process for substituted 5-benzyl-2,4-diamino-pyrimidines
US4255574A (en) * 1973-02-26 1981-03-10 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-pyrimidines
CA1084498A (en) * 1977-05-05 1980-08-26 Alexander E. Wick Benzylpyrimidines and process for the preparation thereof
GR71725B (de) * 1977-11-10 1983-06-22 Hoffmann La Roche
US4258045A (en) * 1979-11-30 1981-03-24 Merck & Co., Inc. Inhibitor of dihydrofolate reductase

Also Published As

Publication number Publication date
IT1138146B (it) 1986-09-17
ATE16800T1 (de) 1985-12-15
EP0071741A1 (de) 1983-02-16
EP0071741B1 (de) 1985-12-04
YU161382A (en) 1985-03-20
US4485248A (en) 1984-11-27
CA1182819A (en) 1985-02-19
ES8304950A1 (es) 1983-04-01
MX156026A (es) 1988-06-16
ES514224A0 (es) 1983-04-01
DE3267778D1 (en) 1986-01-16
IT8123462A0 (it) 1981-08-11

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