AR218872A1 - Procedimiento para la preparacion de derivados de (n,n-dialquil(c1-c4)o pirrolidin-1-ilo,piperidin-1-ilo o morfolidin-1-ilo-alquil(c2-c4)-tio)-n,n-dialquil(c1-c4-isotiourea o imidazolin-2-ilo - Google Patents
Procedimiento para la preparacion de derivados de (n,n-dialquil(c1-c4)o pirrolidin-1-ilo,piperidin-1-ilo o morfolidin-1-ilo-alquil(c2-c4)-tio)-n,n-dialquil(c1-c4-isotiourea o imidazolin-2-iloInfo
- Publication number
- AR218872A1 AR218872A1 AR267623A AR26762377A AR218872A1 AR 218872 A1 AR218872 A1 AR 218872A1 AR 267623 A AR267623 A AR 267623A AR 26762377 A AR26762377 A AR 26762377A AR 218872 A1 AR218872 A1 AR 218872A1
- Authority
- AR
- Argentina
- Prior art keywords
- ilo
- dialquil
- morfolidin
- isotiourea
- pirrolidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB19994/76A GB1592453A (en) | 1976-05-14 | 1976-05-14 | Aminoalkyl esters of carbarimidothioic acid and compositions having immunosuppressant activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR218872A1 true AR218872A1 (es) | 1980-07-15 |
Family
ID=10138568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR267623A AR218872A1 (es) | 1976-05-14 | 1977-05-13 | Procedimiento para la preparacion de derivados de (n,n-dialquil(c1-c4)o pirrolidin-1-ilo,piperidin-1-ilo o morfolidin-1-ilo-alquil(c2-c4)-tio)-n,n-dialquil(c1-c4-isotiourea o imidazolin-2-ilo |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4294854A (fi) |
| JP (1) | JPS532420A (fi) |
| AR (1) | AR218872A1 (fi) |
| AT (1) | AT359521B (fi) |
| AU (1) | AU509573B2 (fi) |
| BE (1) | BE854553A (fi) |
| CA (1) | CA1086758A (fi) |
| CH (1) | CH620203A5 (fi) |
| DE (1) | DE2721830A1 (fi) |
| DK (1) | DK211277A (fi) |
| ES (1) | ES458756A1 (fi) |
| FI (1) | FI771400A (fi) |
| FR (2) | FR2351098A1 (fi) |
| GB (1) | GB1592453A (fi) |
| HU (1) | HU174978B (fi) |
| IE (1) | IE45144B1 (fi) |
| IL (1) | IL52011A (fi) |
| LU (1) | LU77332A1 (fi) |
| NL (1) | NL7705331A (fi) |
| NO (1) | NO771697L (fi) |
| PT (1) | PT66509B (fi) |
| SE (1) | SE7705658L (fi) |
| ZA (1) | ZA772612B (fi) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0672244B2 (ja) * | 1984-12-12 | 1994-09-14 | 三菱マテリアル株式会社 | 貴金属造粒装置 |
| AU695120B2 (en) * | 1993-06-07 | 1998-08-06 | Baylor College Of Medicine | Use of an MHC class I suppressor drug for the treatment of autoimmune diseases and transplantation rejection |
| EP0776886A4 (en) * | 1994-08-18 | 1999-05-12 | Chugai Pharmaceutical Co Ltd | AMINO ACID DERIVATIVE WITH NITROGEN MONOXIDE SYNTHETASE INHIBITING ACTIVITY |
| US7645873B2 (en) * | 2003-03-20 | 2010-01-12 | The Scripps Research Institute | 6″-amino-6″-deoxygalactosylceramides |
| EP2058011A1 (en) * | 2007-11-07 | 2009-05-13 | Wittycell | Nkt cell activating gycolipids covalently bound antigens and/or drug |
| MX338827B (es) * | 2008-10-08 | 2016-05-03 | Vincent Serra | Composicion de vacuna para uso contra influenza. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2648710A (en) * | 1950-09-22 | 1953-08-11 | Hoffmann La Roche | Bis-quaternary salts of 1:10-bis-(dialkylamino)-5:6-dithia-decane |
| US2813102A (en) * | 1956-04-10 | 1957-11-12 | American Home Prod | 2-(di-lower alkylaminoethylmercapto)-imidazolines and their acid addition salts and preparation thereof |
| US4152453A (en) * | 1975-12-01 | 1979-05-01 | Smith Kline & French Laboratories Limited | Pharmacologically active compounds and compositions and methods of use |
-
1976
- 1976-05-14 GB GB19994/76A patent/GB1592453A/en not_active Expired
-
1977
- 1977-05-02 ZA ZA00772612A patent/ZA772612B/xx unknown
- 1977-05-03 FI FI771400A patent/FI771400A/fi not_active Application Discontinuation
- 1977-05-04 IL IL52011A patent/IL52011A/xx unknown
- 1977-05-04 PT PT66509A patent/PT66509B/pt unknown
- 1977-05-04 AT AT318277A patent/AT359521B/de not_active IP Right Cessation
- 1977-05-10 IE IE947/77A patent/IE45144B1/en unknown
- 1977-05-11 CH CH589877A patent/CH620203A5/fr not_active IP Right Cessation
- 1977-05-11 JP JP5483077A patent/JPS532420A/ja active Pending
- 1977-05-11 AU AU25079/77A patent/AU509573B2/en not_active Expired
- 1977-05-12 BE BE177510A patent/BE854553A/xx not_active IP Right Cessation
- 1977-05-13 HU HU77SI1576A patent/HU174978B/hu unknown
- 1977-05-13 AR AR267623A patent/AR218872A1/es active
- 1977-05-13 DE DE19772721830 patent/DE2721830A1/de not_active Withdrawn
- 1977-05-13 FR FR7714766A patent/FR2351098A1/fr active Granted
- 1977-05-13 NL NL7705331A patent/NL7705331A/xx not_active Application Discontinuation
- 1977-05-13 DK DK211277A patent/DK211277A/da not_active Application Discontinuation
- 1977-05-13 CA CA278,412A patent/CA1086758A/en not_active Expired
- 1977-05-13 NO NO771697A patent/NO771697L/no unknown
- 1977-05-13 ES ES458756A patent/ES458756A1/es not_active Expired
- 1977-05-13 LU LU77332A patent/LU77332A1/xx unknown
- 1977-05-16 SE SE7705658A patent/SE7705658L/xx unknown
-
1979
- 1979-10-09 US US06/082,836 patent/US4294854A/en not_active Expired - Lifetime
-
1980
- 1980-11-17 FR FR8024334A patent/FR2472935A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE2721830A1 (de) | 1977-11-24 |
| NO771697L (no) | 1977-11-15 |
| GB1592453A (en) | 1981-07-08 |
| LU77332A1 (fi) | 1977-08-29 |
| AU2507977A (en) | 1978-11-16 |
| SE7705658L (sv) | 1977-11-15 |
| DK211277A (da) | 1977-11-15 |
| HU174978B (hu) | 1980-04-28 |
| IE45144B1 (en) | 1982-06-30 |
| NL7705331A (nl) | 1977-11-16 |
| PT66509A (en) | 1977-06-01 |
| ATA318277A (de) | 1980-04-15 |
| CA1086758A (en) | 1980-09-30 |
| ZA772612B (en) | 1978-04-26 |
| IE45144L (en) | 1977-11-14 |
| AT359521B (de) | 1980-11-10 |
| CH620203A5 (fi) | 1980-11-14 |
| FR2351098A1 (fr) | 1977-12-09 |
| US4294854A (en) | 1981-10-13 |
| IL52011A (en) | 1982-05-31 |
| FI771400A (fi) | 1977-11-15 |
| JPS532420A (en) | 1978-01-11 |
| FR2472935A1 (fr) | 1981-07-10 |
| ES458756A1 (es) | 1978-03-01 |
| AU509573B2 (en) | 1980-05-15 |
| FR2351098B1 (fi) | 1982-06-18 |
| PT66509B (en) | 1978-10-16 |
| BE854553A (fr) | 1977-11-14 |
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