AR204899A1 - PROCEDURE FOR THE PREPARATION OF 3-CARBAMOYLOXIMETHYLCHALOSPORINS - Google Patents

PROCEDURE FOR THE PREPARATION OF 3-CARBAMOYLOXIMETHYLCHALOSPORINS

Info

Publication number
AR204899A1
AR204899A1 AR24020972A AR24020972A AR204899A1 AR 204899 A1 AR204899 A1 AR 204899A1 AR 24020972 A AR24020972 A AR 24020972A AR 24020972 A AR24020972 A AR 24020972A AR 204899 A1 AR204899 A1 AR 204899A1
Authority
AR
Argentina
Prior art keywords
carbamoyloximethylchalosporins
procedure
preparation
Prior art date
Application number
AR24020972A
Other languages
Spanish (es)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of AR204899A1 publication Critical patent/AR204899A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
AR24020972A 1971-01-27 1972-01-01 PROCEDURE FOR THE PREPARATION OF 3-CARBAMOYLOXIMETHYLCHALOSPORINS AR204899A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB329571A GB1350772A (en) 1971-01-27 1971-01-27 Antibiotics and processes for their production
GB2852271 1971-06-17
GB3965471 1971-08-24
GB182972 1972-01-14

Publications (1)

Publication Number Publication Date
AR204899A1 true AR204899A1 (en) 1976-03-19

Family

ID=27447180

Family Applications (1)

Application Number Title Priority Date Filing Date
AR24020972A AR204899A1 (en) 1971-01-27 1972-01-01 PROCEDURE FOR THE PREPARATION OF 3-CARBAMOYLOXIMETHYLCHALOSPORINS

Country Status (10)

Country Link
JP (1) JPS5418274B1 (en)
AR (1) AR204899A1 (en)
AU (1) AU468248B2 (en)
BE (1) BE778508A (en)
CA (1) CA1003404A (en)
CH (1) CH569021A5 (en)
DE (1) DE2203653C3 (en)
FR (1) FR2161866B1 (en)
GB (1) GB1350772A (en)
IE (1) IE36192B1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905963A (en) * 1972-01-25 1975-09-16 Lilly Co Eli Process for preparing primary 3-carbamoyloxymethyl cephalosporins
US3994875A (en) * 1974-06-24 1976-11-30 Yeda Research & Development Co. Ltd. Antibiotics
WO1992019286A1 (en) * 1991-05-03 1992-11-12 University Technologies International, Inc. Biofilm reduction method
WO2004083217A1 (en) * 2003-03-20 2004-09-30 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of cefoxitin
CN101830913B (en) * 2010-04-09 2012-10-31 烟台宝华生物技术有限公司 Cephalosporins parent nucleus derived compound, cephem onium salt compound prepared by same and method for preparing cephalosporins pyrazol sulfate by adopting same
CN103848851B (en) * 2012-11-29 2016-03-02 上海交通大学 A kind of synthetic method of Method of cefcapene pivoxil hydrochloride
EP4252794A1 (en) 2019-01-29 2023-10-04 Nipro Corporation Artificial lung device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1445633A1 (en) 1963-10-07 1968-12-05 Ciba Geigy Process for the preparation of new amides
CH480365A (en) * 1965-01-18 1969-10-31 Ciba Geigy Process for the preparation of new derivatives of 7-aminocephalosporanic acid

Also Published As

Publication number Publication date
DE2203653B2 (en) 1974-12-19
DE2203653A1 (en) 1972-08-10
BE778508A (en) 1972-07-26
FR2161866B1 (en) 1975-08-01
CH569021A5 (en) 1975-11-14
JPS5418274B1 (en) 1979-07-06
DE2203653C3 (en) 1975-07-31
AU468248B2 (en) 1976-01-08
IE36192L (en) 1972-07-27
GB1350772A (en) 1974-04-24
IE36192B1 (en) 1976-09-15
FR2161866A1 (en) 1973-07-13
CA1003404A (en) 1977-01-11
AU3835672A (en) 1973-08-02

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