FR2161866B1 - - Google Patents

Info

Publication number
FR2161866B1
FR2161866B1 FR7202751A FR7202751A FR2161866B1 FR 2161866 B1 FR2161866 B1 FR 2161866B1 FR 7202751 A FR7202751 A FR 7202751A FR 7202751 A FR7202751 A FR 7202751A FR 2161866 B1 FR2161866 B1 FR 2161866B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7202751A
Other languages
French (fr)
Other versions
FR2161866A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2161866A1 publication Critical patent/FR2161866A1/fr
Application granted granted Critical
Publication of FR2161866B1 publication Critical patent/FR2161866B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/577-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7202751A 1971-01-27 1972-01-27 Expired FR2161866B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB329571A GB1350772A (en) 1971-01-27 1971-01-27 Antibiotics and processes for their production
GB2852271 1971-06-17
GB3965471 1971-08-24
GB182972 1972-01-14

Publications (2)

Publication Number Publication Date
FR2161866A1 FR2161866A1 (en) 1973-07-13
FR2161866B1 true FR2161866B1 (en) 1975-08-01

Family

ID=27447180

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7202751A Expired FR2161866B1 (en) 1971-01-27 1972-01-27

Country Status (10)

Country Link
JP (1) JPS5418274B1 (en)
AR (1) AR204899A1 (en)
AU (1) AU468248B2 (en)
BE (1) BE778508A (en)
CA (1) CA1003404A (en)
CH (1) CH569021A5 (en)
DE (1) DE2203653C3 (en)
FR (1) FR2161866B1 (en)
GB (1) GB1350772A (en)
IE (1) IE36192B1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905963A (en) * 1972-01-25 1975-09-16 Lilly Co Eli Process for preparing primary 3-carbamoyloxymethyl cephalosporins
US3994875A (en) * 1974-06-24 1976-11-30 Yeda Research & Development Co. Ltd. Antibiotics
WO1992019286A1 (en) * 1991-05-03 1992-11-12 University Technologies International, Inc. Biofilm reduction method
WO2004083217A1 (en) * 2003-03-20 2004-09-30 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of cefoxitin
CN101830913B (en) * 2010-04-09 2012-10-31 烟台宝华生物技术有限公司 Cephalosporins parent nucleus derived compound, cephem onium salt compound prepared by same and method for preparing cephalosporins pyrazol sulfate by adopting same
CN103848851B (en) * 2012-11-29 2016-03-02 上海交通大学 A kind of synthetic method of Method of cefcapene pivoxil hydrochloride
EP4233934A3 (en) 2019-01-29 2023-10-04 Nipro Corporation Artificial lung device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1445633A1 (en) 1963-10-07 1968-12-05 Ciba Geigy Process for the preparation of new amides
CH480365A (en) * 1965-01-18 1969-10-31 Ciba Geigy Process for the preparation of new derivatives of 7-aminocephalosporanic acid

Also Published As

Publication number Publication date
AU468248B2 (en) 1976-01-08
IE36192L (en) 1972-07-27
CA1003404A (en) 1977-01-11
IE36192B1 (en) 1976-09-15
CH569021A5 (en) 1975-11-14
BE778508A (en) 1972-07-26
AU3835672A (en) 1973-08-02
AR204899A1 (en) 1976-03-19
DE2203653B2 (en) 1974-12-19
DE2203653A1 (en) 1972-08-10
FR2161866A1 (en) 1973-07-13
JPS5418274B1 (en) 1979-07-06
GB1350772A (en) 1974-04-24
DE2203653C3 (en) 1975-07-31

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