AR119705A1 - Formulaciones liposomales y sus métodos de uso y preparación - Google Patents

Formulaciones liposomales y sus métodos de uso y preparación

Info

Publication number
AR119705A1
AR119705A1 ARP200100841A ARP200100841A AR119705A1 AR 119705 A1 AR119705 A1 AR 119705A1 AR P200100841 A ARP200100841 A AR P200100841A AR P200100841 A ARP200100841 A AR P200100841A AR 119705 A1 AR119705 A1 AR 119705A1
Authority
AR
Argentina
Prior art keywords
preparation
methods
liposome
liposomal formulations
polar headgroup
Prior art date
Application number
ARP200100841A
Other languages
English (en)
Inventor
Samuel Eric Greenberg
Teppei Shirakura
Agnes Rafalko
Original Assignee
Glycomine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glycomine Inc filed Critical Glycomine Inc
Publication of AR119705A1 publication Critical patent/AR119705A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reivindicación 1: Una composición que comprende: un liposoma que comprende: i) 1,2-dioleoil-sn-glicero-3-fosfoetanolamina o una de sus sales; y ii) (a) uno o más fosfolípidos que tienen un grupo de cabeza polar, en donde el grupo de cabeza polar comprende glicerol, colina, fosfato y serina y una cola de ácido graso que comprende una cadena alifática C₁₀₋₂₈ o (b) un éster de colesterol ácido, o tanto (a) como (b); y iii) polietilenglicol (PEG) conjugado con al menos un fosfolípido; y al menos un carbohidrato fosforilado endógeno encapsulado en el liposoma.
ARP200100841A 2019-03-29 2020-03-27 Formulaciones liposomales y sus métodos de uso y preparación AR119705A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962826874P 2019-03-29 2019-03-29

Publications (1)

Publication Number Publication Date
AR119705A1 true AR119705A1 (es) 2022-01-05

Family

ID=72666933

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP200100841A AR119705A1 (es) 2019-03-29 2020-03-27 Formulaciones liposomales y sus métodos de uso y preparación

Country Status (18)

Country Link
US (1) US20220184107A1 (es)
EP (1) EP3946365A4 (es)
JP (1) JP2022527638A (es)
KR (1) KR20210143906A (es)
CN (1) CN113873998A (es)
AR (1) AR119705A1 (es)
AU (1) AU2020252005A1 (es)
BR (1) BR112021019593A2 (es)
CA (1) CA3134828A1 (es)
CL (1) CL2021002512A1 (es)
CO (1) CO2021014274A2 (es)
EA (1) EA202192663A1 (es)
IL (1) IL286713A (es)
MX (1) MX2021011876A (es)
PE (1) PE20212366A1 (es)
SG (1) SG11202110623PA (es)
TW (1) TW202102231A (es)
WO (1) WO2020205530A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023205628A1 (en) * 2022-04-18 2023-10-26 City Of Hope Lipid nanoparticles, nucleic acids, and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010112301A (ko) * 1999-03-02 2001-12-20 질레스피 카롤 리포좀내에 생활성 복합체의 포집
US7060291B1 (en) * 1999-11-24 2006-06-13 Transave, Inc. Modular targeted liposomal delivery system
EP1385479A4 (en) * 2001-03-26 2006-12-06 Alza Corp LIPOSOMIC COMPOSITION FOR IMPROVED INTRA-CELLULAR RELEASE OF A THERAPEUTIC AGENT
AU2003205049B2 (en) * 2002-01-09 2009-05-28 Transave, Inc. Efficient nucleic acid encapsulation into medium sized liposomes
US20090191259A1 (en) * 2002-01-09 2009-07-30 Transave, Inc. Efficient liposomal encapsulation
EP2429658B1 (fr) * 2009-05-14 2016-04-20 Sanofi Pasteur Procédé pour adjuver le lipopolysaccharide (LPS) des bactéries à gram-négatif
LT3046537T (lt) * 2013-09-16 2021-12-10 Glycomine, Inc. Farmacinis angliavandenių preparatas, skirtas terapiniam panaudojimui
US20170165374A1 (en) * 2015-11-18 2017-06-15 Insmed, Inc. Compositions and methods for treating bacterial infections

Also Published As

Publication number Publication date
JP2022527638A (ja) 2022-06-02
CN113873998A (zh) 2021-12-31
SG11202110623PA (en) 2021-10-28
PE20212366A1 (es) 2021-12-21
TW202102231A (zh) 2021-01-16
WO2020205530A1 (en) 2020-10-08
KR20210143906A (ko) 2021-11-29
CO2021014274A2 (es) 2022-01-17
EP3946365A4 (en) 2023-04-19
US20220184107A1 (en) 2022-06-16
MX2021011876A (es) 2022-01-04
EP3946365A1 (en) 2022-02-09
EA202192663A1 (ru) 2022-03-01
CA3134828A1 (en) 2020-10-08
AU2020252005A1 (en) 2021-11-04
CL2021002512A1 (es) 2023-01-06
IL286713A (en) 2021-10-31
BR112021019593A2 (pt) 2021-12-14

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